LOCUS BC069613 1660 bp mRNA linear HUM 19-JUN-2008
DEFINITION Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 2, mRNA (cDNA
clone MGC:97077 IMAGE:7262289), complete cds.
ACCESSION BC069613
VERSION BC069613.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1660)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1660)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRBR Plate: 3 Row: a Column: 7.
FEATURES Location/Qualifiers
source 1..1660
/db_xref="H-InvDB:HIT000263764"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:97077 IMAGE:7262289"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_277"
/note="Vector: pPCR-Script Amp SK(+) with reversed insert"
gene 1..1660
/gene="PAK2"
/gene_synonym="PAK65"
/gene_synonym="PAKgamma"
/db_xref="GeneID:5062"
/db_xref="HGNC:HGNC:8591"
/db_xref="MIM:605022"
CDS 36..1610
/gene="PAK2"
/gene_synonym="PAK65"
/gene_synonym="PAKgamma"
/codon_start=1
/product="p21 protein (Cdc42/Rac)-activated kinase 2"
/protein_id="AAH69613.1"
/db_xref="GeneID:5062"
/db_xref="HGNC:HGNC:8591"
/db_xref="MIM:605022"
/translation="MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVP
EEKKPRHKIISIFSGTEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQW
ARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAK
GTEAPAVVTEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSL
DKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQRASGTVFTATDVALGQEVA
IKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDV
VTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQ
ITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR
ALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSS
LTPLIMAAKEAMKSNR"
BASE COUNT 521 a 354 c 379 g 406 t
ORIGIN
1 ttggcttgcc cggggccatt tcataattct gaatcatgtc tgataacgga gaactggaag
61 ataagcctcc agcacctcct gtgcgaatga gcagcaccat ctttagcact ggaggcaaag
121 accctttgtc agccaatcac agtttgaaac ctttgccctc tgttccagaa gagaaaaagc
181 ccaggcataa aatcatctcc atattctcag gcacagagaa aggaagtaaa aagaaggaaa
241 aggaacggcc agaaatttct cctccatctg attttgagca caccatccat gttggttttg
301 atgctgttac tggagaattc actggcatgc cagaacagtg ggctcgatta ctacagacct
361 ccaatatcac caaactagag caaaagaaga accctcaggc tgtgctggat gtcctaaagt
421 tctacgactc caacacagtg aagcagaaat atctgagctt tactcctcct gagaaagatg
481 gctttccttc tggaacacca gcactgaatg ccaagggaac agaagcaccc gcagtagtga
541 cagaggagga ggatgatgat gaagagactg ctcctcccgt tattgccccg cgaccggatc
601 atacgaaatc aatttacaca cggtctgtaa ttgaccctgt tcctgcacca gttggtgatt
661 cacatgttga tggtgctgcc aagtctttag acaaacagaa aaagaagact aagatgacag
721 atgaagagat tatggagaaa ttaagaacta tcgtgagcat aggtgaccct aagaaaaaat
781 atacaagata tgaaaaaatt ggacaaaggg cttctggtac agttttcact gctactgacg
841 ttgcactggg acaggaggtt gctatcaaac aaattaattt acagaaacag ccaaagaagg
901 aactgatcat taacgagatt ctggtgatga aagaattgaa aaatcccaac atcgttaact
961 ttttggacag ttacctggta ggagatgaat tgtttgtggt catggaatac cttgctgggg
1021 ggtcactcac tgatgtggta acagaaacgt gcatggatga agcacagatt gctgctgtat
1081 gcagagagtg tttacaggca ttggagtttt tacatgctaa tcaagtgatc cacagagaca
1141 tcaaaagtga caatgtactt ttgggaatgg aaggatctgt taagctcact gactttggtt
1201 tctgtgccca gatcacccct gagcagagca aacgcagtac catggtcgga acgccatact
1261 ggatggcacc agaggtggtt acacggaaag cttatggccc taaagtcgac atatggtctc
1321 tgggtatcat ggctattgag atggtagaag gagagcctcc atacctcaat gaaaatccct
1381 tgagggcctt gtacctaata gcaactaatg gaaccccaga acttcagaat ccagagaaac
1441 tttccccaat atttcgggat ttcttaaatc gatgtttgga aatggatgtg gaaaaaaggg
1501 gttcagccaa agaattatta cagcatcctt tcctgaaact ggccaaaccg ttatctagct
1561 tgacaccact gatcatggca gctaaagaag caatgaagag taaccgttaa catcactgct
1621 gtggcctcat actctttttt ccattttcta caagaagcct
//