LOCUS BC069388 1891 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens interleukin-1 receptor-associated kinase 3, mRNA (cDNA
clone MGC:97088 IMAGE:7262303), complete cds.
ACCESSION BC069388
VERSION BC069388.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1891)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1891)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRBR Plate: 3 Row: b Column: 9.
FEATURES Location/Qualifiers
source 1..1891
/db_xref="H-InvDB:HIT000263539"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:97088 IMAGE:7262303"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_277"
/note="Vector: pPCR-Script Amp SK(+) with reversed insert"
gene 1..1891
/gene="IRAK3"
/gene_synonym="IRAK-M"
/db_xref="GeneID:11213"
/db_xref="HGNC:HGNC:17020"
/db_xref="MIM:604459"
CDS 51..1841
/gene="IRAK3"
/gene_synonym="IRAK-M"
/codon_start=1
/product="interleukin-1 receptor-associated kinase 3"
/protein_id="AAH69388.1"
/db_xref="GeneID:11213"
/db_xref="HGNC:HGNC:17020"
/db_xref="MIM:604459"
/translation="MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGL
AERLSSSWLDVRHIEKYVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLI
TNYGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGVLLKSSISFQNIIE
GTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLL
FHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISK
AIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSS
SKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELME
KRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASL
YFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFE
CSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSE
APGHSCRSRPVESSCSSKFSWDEYEQYKKE"
BASE COUNT 567 a 401 c 442 g 481 t
ORIGIN
1 gtgcagggac ctggactccg cctcgtcccc ggggctcggg cagccgagcc atggcgggga
61 actgtggggc ccgcggcgcg ctgtcggcgc acacgctgct gttcgacctg ccgcccgcgc
121 tgctcggaga gctctgcgct gttctggaca gctgcgacgg cgcgctgggt tggcgcggcc
181 tggcagagag actttcaagc agctggctgg atgttcgtca tattgaaaag tatgtagacc
241 aaggtaaaag tggaacaaga gaattacttt ggtcctgggc acagaaaaac aagaccatcg
301 gtgacctttt acaggtcctc caggagatgg gacatcgtcg agctattcat ttaattacaa
361 actatggagc agtgttgagt ccttcagaga agagttatca ggaaggtgga tttccaaata
421 tattattcaa ggaaacagcc aatgtcaccg tggataatgt tcttattcct gaacataatg
481 aaaaaggagt actgcttaaa tcttccatca gctttcaaaa tatcatagaa ggaactagaa
541 atttccacaa agacttccta attggagaag gagagatttt tgaggtatac agagtggaga
601 ttcaaaacct aacatatgct gtcaaattat ttaaacagga gaaaaaaatg cagtgtaaga
661 agcattggaa gaggttttta tctgagcttg aagttttact actgtttcat cacccaaaca
721 tactagagtt ggctgcatat tttacagaga ctgagaagtt ctgtctgatt tatccataca
781 tgagaaatgg aacacttttt gacagattgc agtgtgtagg tgacacggcc ccactccctt
841 ggcacattcg aatcggtata ttaataggaa tatccaaagc cattcactac ctgcacaacg
901 ttcaaccatg ctcggtcatc tgtggcagta tatcaagtgc aaacatcctt ttggatgatc
961 agtttcaacc caaactaact gattttgcca tggcacactt ccggtcccac ctagaacatc
1021 agagttgtac cataaatatg accagcagca gcagtaaaca tctgtggtac atgccagaag
1081 agtacatcag acaggggaaa ctttccatta aaacagatgt ctacagcttt ggaattgtaa
1141 taatggaagt tctaacagga tgtagagtag tgttagatga tccaaaacat atccagctgc
1201 gggatctcct tagagaattg atggagaaga gaggcctgga ttcatgtctc tcatttctag
1261 ataagaaagt gcctccctgc cctcggaatt tctctgccaa gctcttctgt ttggcaggcc
1321 ggtgtgctgc aacgcgggca aagttaagac catcaatgga tgaagtttta aatactcttg
1381 aaagtactca agccagcttg tattttgctg aagatcctcc cacatcacta aagtccttca
1441 ggtgtccttc tcctctattc ctggagaatg taccaagtat tccagtggaa gatgatgaaa
1501 gccagaataa caatttacta ccttctgatg aaggcctgag gatagacaga atgactcaga
1561 aaactccttt tgaatgcagc cagtctgagg ttatgtttct gagcttggac aaaaagccag
1621 agagcaagag aaatgaggaa gcttgcaaca tgcccagttc ttcttgtgaa gaaagttggt
1681 tcccaaagta tatagttcca tcccaggact taaggcccta taaggtaaat atagatcctt
1741 cttcagaagc tccagggcat tcttgcagga gcaggccagt ggagagcagc tgttcctcca
1801 aattttcctg ggatgaatat gaacagtaca aaaaagaata aattctacca gaagataaag
1861 aaaaaagcaa gtattgcata ggcacctgag c
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