LOCUS BC069274 3462 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldehyde dehydrogenase 1 family, member A3, mRNA (cDNA
clone MGC:78582 IMAGE:6208628), complete cds.
ACCESSION BC069274
VERSION BC069274.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3462)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3462)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 54 Row: i Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4502040.
FEATURES Location/Qualifiers
source 1..3462
/db_xref="H-InvDB:HIT000263427"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:78582 IMAGE:6208628"
/tissue_type="Pancreas, ductal carcinoma"
/clone_lib="NIH_MGC_110"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3462
/gene="ALDH1A3"
/gene_synonym="ALDH1A6"
/gene_synonym="RALDH3"
/db_xref="GeneID:220"
/db_xref="HGNC:HGNC:409"
/db_xref="MIM:600463"
CDS 57..1595
/gene="ALDH1A3"
/gene_synonym="ALDH1A6"
/gene_synonym="RALDH3"
/codon_start=1
/product="aldehyde dehydrogenase 1 family, member A3"
/protein_id="AAH69274.1"
/db_xref="GeneID:220"
/db_xref="HGNC:HGNC:409"
/db_xref="MIM:600463"
/translation="MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESK
SGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQ
LADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDD
NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGS
LIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKR
VTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRS
VEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLF
IKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK
ALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG
DKNP"
BASE COUNT 934 a 763 c 867 g 898 t
ORIGIN
1 gccgagccgg tgcgccgcag actagggcgc ctcgggccag ggagcgcgga ggagccatgg
61 ccaccgctaa cggggccgtg gaaaacgggc agccggacag gaagccgccg gccctgccgc
121 gccccatccg caacctggag gtcaagttca ccaagatatt tatcaacaat gaatggcacg
181 aatccaagag tgggaaaaag tttgctacat gtaacccttc aactcgggag caaatatgtg
241 aagtggaaga aggagataag cccgacgtgg acaaggctgt ggaggctgca caggttgcct
301 tccagagggg ctcgccatgg cgccggctgg atgccctgag tcgtgggcgg ctgctgcacc
361 agctggctga cctggtggag agggaccgcg ccaccttggc cgccctggag acgatggata
421 cagggaagcc atttcttcat gcttttttca tcgacctgga gggctgtatt agaaccctca
481 gatactttgc agggtgggca gacaaaatcc agggcaagac catccccaca gatgacaacg
541 tcgtgtgctt caccaggcat gagcccattg gtgtctgtgg ggccatcact ccatggaact
601 tccccctgct gatgctggtg tggaagctgg cacccgccct ctgctgtggg aacaccatgg
661 tcctgaagcc tgcggagcag acacctctca ccgcccttta tctcggctct ctgatcaaag
721 aggccgggtt ccctccagga gtggtgaaca ttgtgccagg attcgggccc acagtgggag
781 cagcaatttc ttctcaccct cagatcaaca agatcgcctt caccggctcc acagaggttg
841 gaaaactggt taaagaagct gcgtcccgga gcaatctgaa gcgggtgacg ctggagctgg
901 gggggaagaa cccctgcatc gtgtgtgcgg acgctgactt ggacttggca gtggagtgtg
961 cccatcaggg agtgttcttc aaccaaggcc agtgttgcac ggcagcctcc agggtgttcg
1021 tggaggagca ggtctactct gagtttgtca ggcggagcgt ggagtatgcc aagaaacggc
1081 ccgtgggaga ccccttcgat gtcaaaacag aacaggggcc tcagattgat caaaagcagt
1141 tcgacaaaat cttagagctg atcgagagtg ggaagaagga aggggccaag ctggaatgcg
1201 ggggctcagc catggaagac aaggggctct tcatcaaacc cactgtcttc tcagaagtca
1261 cagacaacat gcggattgcc aaagaggaga ttttcgggcc agtgcaacca atactgaagt
1321 tcaaaagtat cgaagaagtg ataaaaagag cgaatagcac cgactatgga ctcacagcag
1381 ccgtgttcac aaaaaatctc gacaaagccc tgaagttggc ttctgcctta gagtctggaa
1441 cggtctggat caactgctac aacgccctct atgcacaggc tccatttggt ggctttaaaa
1501 tgtcaggaaa tggcagagaa ctaggtgaat acgctttggc cgaatacaca gaagtgaaaa
1561 ctgtcaccat caaacttggc gacaagaacc cctgaaggaa aggcggggct ccttcctcaa
1621 acatcggacg gcggaatgtg gcagatgaaa tgtgctggag gaaaaaaatg acatttctga
1681 ccttcccggg acacattctt ctggaggctt tacatctact ggagttgaat gattgctgtt
1741 ttcctctcac tctcctgttt attcaccaga ctggggatgc ctataggttg tctgtgaaat
1801 cgcagtcctg cctggggagg gagctgttgg ccatttctgt gtttcccttt aaaccagatc
1861 ctggagacag tgagatactc agggcgttgt taacagggag tggtatttga agtgtccagc
1921 agttgcttga aatgctttgc cgaatctgac tccagtaaga atgtgggaaa accccctgtg
1981 tgttctgcaa gcagggctct tgcaccagcg gtctcctcag ggtggacctg cttacagagc
2041 aagccacgcc tctttccgag gtgaaggtgg gaccattcct tgggaaagga ttcacagtaa
2101 ggttttttgg tttttgtttt ttgttttctt gtttttaaaa aaaggatttc acagtgagaa
2161 agttttggtt agtgcatacc gtggaagggc gccagggtct ttgtggattg catgttgaca
2221 ttgaccgtga gattcggctt caaaccaata ctgcctttgg aatatgacag aatcaatagc
2281 ccagagagct tagtcaaaga cgatatcacg gtctacctta accaaggcac tttcttaagc
2341 agaaaatatt gttgaggtta cctttgctgc taaagatcca atcttctaac gccacaacag
2401 catagcaaat cctaggataa ttcacctcct catttgacaa atcagagctg taattcgctt
2461 taacaaatta cgcatttcta tcacgttcac taacagctta tgataagtct gtgtagtctt
2521 ccttttctcc agttctgtta cccaatttag attagtaaag cgtacacaac tggaaagact
2581 gctgtaataa cacagccttg ttatttttaa gtcctatttt gatattaatt tctgattagt
2641 tagtaaataa cacctggatt ctatggagga cctcggtctt catccaagtg gcctgagtat
2701 ttcactggca ggttgtgaat ttttcttttc ctctttgggg atccaaatga tgatgtgcaa
2761 tttcatgttt taacttggga aactgaaagt gttcccatat agcttcaaaa acaaaaacaa
2821 atgtgttatc cgacggatac ttttatggtt actaactagt actttcctaa ttgggaaagt
2881 agtgcttaag tttgcaaatt aagttgggga gggcaataat aaaatgaggg cccgtaacag
2941 aaccagtgtg tgtataacga aaaccatgta taaaatgggc ctatcaccct tgtcagagat
3001 ataaattacc acatttgcct tcccttcatc agctaacact tatcacttat actaccaata
3061 acttgttaaa tcaggatttg gcttcataca ctgaattttc agtattttat ctcaagtaga
3121 tatagacact aaccttgata gtgatacgtt agagggttcc tattcttcca ttgtacgata
3181 atgtctttaa tatgaaatgc tacattattt ataattggta gagttattgt atctttttat
3241 agttgtaagt acacagaggt ggtatattta aacttctgta atatactgta tttagaaatg
3301 gaaatatata tagtgttagg tttcacttct tttaaggttt acccctgtgg tgtggtttaa
3361 aaatctatag gcctgggaat tccgatccta gctgcagatc gcatcccaca atgcgagaat
3421 gataaaataa aattggatat ttgagaaaaa aaaaaaaaaa aa
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