LOCUS BC068996 1808 bp mRNA linear HUM 27-APR-2004
DEFINITION Homo sapiens nuclear receptor co-repressor 1, mRNA (cDNA clone
IMAGE:5474358), partial cds.
ACCESSION BC068996
VERSION BC068996.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1808)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1808)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 54 Row: g Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22538460.
FEATURES Location/Qualifiers
source 1..1808
/db_xref="H-InvDB:HIT000263180"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5474358"
/tissue_type="Skin, melanoma, amelanotic"
/clone_lib="NIH_MGC_41"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>1808
/gene="NCOR1"
/gene_synonym="hCIT529I10"
/gene_synonym="hN-CoR"
/gene_synonym="KIAA1047"
/gene_synonym="N-CoR"
/gene_synonym="TRAC1"
/db_xref="GeneID:9611"
/db_xref="MIM:600849"
CDS 242..>1808
/gene="NCOR1"
/gene_synonym="hCIT529I10"
/gene_synonym="hN-CoR"
/gene_synonym="KIAA1047"
/gene_synonym="N-CoR"
/gene_synonym="TRAC1"
/codon_start=1
/product="NCOR1 protein"
/protein_id="AAH68996.1"
/db_xref="GeneID:9611"
/db_xref="MIM:600849"
/translation="MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYR
SSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHD
SLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPI
SGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPE
PEKPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYH
ENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAK
ESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQEN
NEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKD
KFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIAR
PSQEEKVEEKKKKK"
misc_feature 1553..1690
/gene="NCOR1"
/gene_synonym="hCIT529I10"
/gene_synonym="hN-CoR"
/gene_synonym="KIAA1047"
/gene_synonym="N-CoR"
/gene_synonym="TRAC1"
/note="SANT; Region: SANT SWI3, ADA2, N-CoR and TFIIIB''
DNA-binding domains"
/db_xref="CDD:smart00717"
BASE COUNT 581 a 395 c 435 g 397 t
ORIGIN
1 gtcaagatgg cggccaaggt ggcgaagcag cagccgcggc ggcggcggcg gctggagtga
61 gcgtccgact cgccgcgccg aacgaggtcc cggtgtaggg ccgcgcgccg tggccgcgtc
121 ccactcctca ggccggggcg cacgtcggct cccacgctta gccagctccc ggtggtttcc
181 tagaaacatg attgtttatt ggcattgatc tcacagtctg gtgaggactt ctttactgat
241 aatgtcaagt tcaggttatc ctcccaacca aggagcattc agcacagaac aaagtcgtta
301 tcctcctcac tctgtccagt atacatttcc caacacccgc caccagcagg agttcgcagt
361 ccctgattat cgttcctctc atcttgaagt gagtcaggca tcacagcttt tgcagcaaca
421 gcagcagcaa cagcttcgaa ggcgaccttc cttgctttca gaatttcacc caggttctga
481 caggcctcaa gaaaggagaa ctagttatga accgtttcat ccaggcccat ccccagtgga
541 tcatgattca ctggaatcga agcgaccacg tctggaacag gtttctgatt ctcattttca
601 gcgtgtcagt gctgcggttt tgcctttagt gcacccgctg ccagaagggc tgagggcttc
661 tgcagatgct aagaaggatc cagcattcgg aggcaaacat gaagctccat cctctccaat
721 ttcggggcaa ccatgtggag atgatcaaaa tgcttcacct tcaaaactct caaaggaaga
781 gttaatacag agtatggatc gtgtagatcg agaaattgca aaagtagaac agcagatcct
841 taaactgaaa aagaaacaac aacagcttga agaagaggca gctaaacctc ctgagcctga
901 gaagcccgtg tcccctcctc ctgtggagca gaaacaccgc agtattgtcc aaattattta
961 tgatgagaat cggaaaaaag cagaagaagc tcataaaatt tttgaaggtc ttggcccaaa
1021 agttgaactg ccactgtata accagccatc agataccaag gtgtaccatg agaacatcaa
1081 gacaaaccag gtgatgagga aaaaactcat tttatttttt aaaagaagaa atcatgcaag
1141 aaaacaaagg gaacaaaaaa tctgccagcg ttatgatcag ctcatggagg catgggagaa
1201 aaaagtggac agaatagaaa ataatcctcg gaggaaagct aaagaaagca aaacaaggga
1261 atactatgaa aagcagtttc cagaaattcg aaaacaaaga gaacagcaag aaagatttca
1321 gcgagttggg cagaggggag ctggtctttc agccaccatt gctaggagtg agcatgagat
1381 ttctgaaatt attgatgggc tctctgagca ggagaataat gagaaacaaa tgcggcagct
1441 ctctgtgatt ccacctatga tgtttgatgc agaacaaaga cgagtcaagt tcattaacat
1501 gaatgggctt atggaggacc ctatgaaagt gtataaagat aggcagttta tgaatgtttg
1561 gactgaccat gaaaaggaga tctttaagga caagtttatc cagcatccaa aaaactttgg
1621 actaattgca tcatacttgg agaggaagag tgttcctgat tgtgttttgt attactattt
1681 aaccaagaaa aatgagaatt ataaagccct cgtcagaagg aattatggga aacgcagagg
1741 cagaaaccag cagcaaattg ctcgaccctc gcaagaagaa aaagtagaag aaaaaaaaaa
1801 aaaaaaaa
//