LOCUS BC068991 1728 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens reticulon 4, mRNA (cDNA clone IMAGE:4634289), complete
cds.
ACCESSION BC068991
VERSION BC068991.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1728)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1728)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 54 Row: c Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47519489
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1728
/db_xref="H-InvDB:HIT000263175"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4634289"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1728
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
CDS 249..1370
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/codon_start=1
/product="reticulon 4"
/protein_id="AAH68991.1"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIV
SVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSA
LGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPV
IYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE"
BASE COUNT 372 a 492 c 474 g 390 t
ORIGIN
1 gtccgctggc ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt
61 ggcgcatcac cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac
121 agtaggtccc tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg
181 cccgcggctc tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc
241 ctccagccat ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc
301 ggccgcagcc cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag
361 aggaggagga agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga
421 agcccgccgc cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc
481 tgatggactt cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc
541 cccccgtcgc cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc
601 ccgcgccatc cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg
661 agcctccggc ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg
721 tgtggacccc gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc
781 gcaggggctc ctcgggctca gtggttgttg acctcctgta ctggagagac attaagaaga
841 ctggagtggt gtttggtgcc agcctattcc tgctgctttc attgacagta ttcagcattg
901 tgagcgtaac agcctacatt gccttggccc tgctctctgt gaccatcagc tttaggatat
961 acaagggtgt gatccaagct atccagaaat cagatgaagg ccacccattc agggcatatc
1021 tggaatctga agttgctata tctgaggagt tggttcagaa gtacagtaat tctgctcttg
1081 gtcatgtgaa ctgcacgata aaggaactca ggcgcctctt cttagttgat gatttagttg
1141 attctctgaa gtttgcagtg ttgatgtggg tatttaccta tgttggtgcc ttgtttaatg
1201 gtctgacact actgattttg gctctcattt cactcttcag tgttcctgtt atttatgaac
1261 ggcatcaggc acagatagat cattatctag gacttgcaaa taagaatgtt aaagatgcta
1321 tggctaaaat ccaagcaaaa atccctggat tgaagcgcaa agctgaatga aaacgcccaa
1381 aataattagt aggagttcat ctttaaaggg gatattcatt tgattatacg ggggagggtc
1441 agggaagaac gaaccttgac gttgcagtgc agtttcacag atcgttgtta gatctttatt
1501 tttagccatg cactgttgtg aggaaaaatt acctgtcttg actgccatgt gttcatcatc
1561 ttaagtattg taagctgcta tgtatggatt taaaccgtaa tcatatcttt ttcctatctg
1621 aggcactggt ggaataaaaa acctgtatat tttactttgt tgcagatagt cttgccgcat
1681 cttggcaagt tgcagagatg gtggagctag aaaaaaaaaa aaaaaaaa
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