LOCUS BC068080 1110 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens leucine-rich repeat kinase 1, mRNA (cDNA clone
IMAGE:6209274), complete cds.
ACCESSION BC068080
VERSION BC068080.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1110)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1110)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 54 Row: i Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1110
/db_xref="H-InvDB:HIT000262939"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6209274"
/tissue_type="Pancreas, ductal carcinoma"
/clone_lib="NIH_MGC_110"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1110
/gene="LRRK1"
/gene_synonym="FLJ23119"
/gene_synonym="FLJ27465"
/gene_synonym="KIAA1790"
/gene_synonym="Roco1"
/db_xref="GeneID:79705"
/db_xref="HGNC:HGNC:18608"
CDS 239..1024
/gene="LRRK1"
/gene_synonym="FLJ23119"
/gene_synonym="FLJ27465"
/gene_synonym="KIAA1790"
/gene_synonym="Roco1"
/codon_start=1
/product="LRRK1 protein"
/protein_id="AAH68080.1"
/db_xref="GeneID:79705"
/db_xref="HGNC:HGNC:18608"
/translation="MSQRPPSMYWCVGPEESAVCPERAMETLNGAGDTGGKPSTRGGD
PAARSRRTEGIRAAYRRGDRGGARDLLEEACDQCASQLEKGQLLSIPAAYGDLEMVRY
LLSKRLVELPTEPTDDNPAVVAAYFGHTAVVQELLESLPGPCSPQRLLNWMLALACQR
GHLGVVKLLVLTHGADPESYAVRKNEFPVIVRLPLYAAIKSGNEDIAIFLLRHGAYFC
SYILLDSPDPSKHLLRKYFIEASPLPSSYPGKTVSSHCLWSVF"
BASE COUNT 230 a 321 c 350 g 209 t
ORIGIN
1 ggcgcggggg gcagacggcg gtgggacggc caggccccgg ccccgccagt gtgtccgccc
61 ggccccgcgt cccggagcgc ccgcacccgg ccccgccgcc gcctcagatc aagaaagctt
121 tctgctcagc catggctacg agtccacgcc ttaatgcacc ccacagccag cggcagtggc
181 agtgacaaca gcgggacctg cctttgaaga tcggctgctg caagggttga tggctggcat
241 gtcgcaaaga ccccccagca tgtactggtg tgtggggccg gaggagtcag ctgtgtgtcc
301 agaacgtgcc atggagacgc ttaacggtgc cggggacacg ggcggcaagc cgtccacgcg
361 gggcggtgac cctgcagcgc ggtcccgcag gacggaaggc atccgcgccg cgtacaggcg
421 gggagaccgc ggcggcgccc gggacctgct ggaggaggcc tgcgaccagt gcgcgtccca
481 gctggaaaag ggccagcttc tgagcatccc ggcagcctat ggggatctgg agatggtccg
541 ctacctactc agcaagagac tggtggagct gcccaccgag cccacggatg acaacccagc
601 cgtggtggca gcgtattttg gacacacggc agttgtgcag gaattgcttg agtccttacc
661 aggtccctgc agtccccagc ggcttctgaa ctggatgctg gccttggctt gccagcgagg
721 gcacctgggg gttgtgaagc tcctggtcct gacgcacggg gctgacccgg agagctacgc
781 tgtcaggaag aatgagttcc ctgtcatcgt gcgcttgccc ctgtatgcgg ccatcaagtc
841 agggaatgaa gacattgcaa tattcctgct tcggcatggg gcctatttct gttcctacat
901 cttgctggat agtcctgacc ccagcaaaca tctgctgaga aagtacttca ttgaagccag
961 tcccttgccc agcagttatc cgggaaaaac agtgagtagt cactgcctgt ggagtgtgtt
1021 ttagttcctt ttgtgctgct gtaacagaat cctgcagact gggtaattta taataaacag
1081 aaatatattt ggaaaaaaaa aaaaaaaaaa
//