LOCUS BC067432 1515 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6,
mRNA (cDNA clone MGC:79259 IMAGE:7002157), complete cds.
ACCESSION BC067432
VERSION BC067432.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1515)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1515)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: Bhat Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 172 Row: h Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 68509919.
FEATURES Location/Qualifiers
source 1..1515
/db_xref="H-InvDB:HIT000262590"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:79259 IMAGE:7002157"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_195"
/lab_host="DH10B"
/note="Vector: pDNR-Dual"
gene 1..1515
/gene="CYP2D6"
/gene_synonym="CPD6"
/gene_synonym="CYP2D"
/gene_synonym="CYP2D@"
/gene_synonym="P450-DB1"
/gene_synonym="P450C2D"
/db_xref="GeneID:1565"
/db_xref="HGNC:HGNC:2625"
/db_xref="MIM:124030"
CDS 2..1495
/gene="CYP2D6"
/gene_synonym="CPD6"
/gene_synonym="CYP2D"
/gene_synonym="CYP2D@"
/gene_synonym="P450-DB1"
/gene_synonym="P450C2D"
/codon_start=1
/product="cytochrome P450, family 2, subfamily D,
polypeptide 6"
/protein_id="AAH67432.1"
/db_xref="GeneID:1565"
/db_xref="HGNC:HGNC:2625"
/db_xref="MIM:124030"
/translation="MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLG
NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRP
PVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACL
CAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESG
FLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFL
AEMEKAKGNPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE
IDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKG
TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR
MELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVTPSPYELCAVPR"
BASE COUNT 252 a 514 c 452 g 297 t
ORIGIN
1 tatggggcta gaagcactgg tgcccctggc cgtgatagtg gccatcttcc tgctcctggt
61 ggacctgatg caccggcgcc aacgctgggc tgcacgctac ccaccaggcc ccctgccact
121 gcccgggctg ggcaacctgc tgcatgtgga cttccagaac acaccatact gcttcgacca
181 gttgcggcgc cgcttcgggg acgtgttcag cctgcagctg gcctggacgc cggtggtcgt
241 gctcaatggg ctggcggccg tgcgcgaggc gctggtgacc cacggcgagg acaccgccga
301 ccgcccgcct gtgcccatca cccagatcct gggtttcggg ccgcgttccc aaggggtgtt
361 cctggcgcgc tatgggcccg cgtggcgcga gcagaggcgc ttctccgtct ccaccttgcg
421 caacttgggc ctgggcaaga agtcgctgga gcagtgggtg accgaggagg ccgcctgcct
481 ttgtgccgcc ttcgccaacc actccggacg cccctttcgc cccaacggtc tcttggacaa
541 agccgtgagc aacgtgatcg cctccctcac ctgcgggcgc cgcttcgagt acgacgaccc
601 tcgcttcctc aggctgctgg acctagctca ggagggactg aaggaggagt cgggctttct
661 gcgcgaggtg ctgaatgctg tccccgtcct cctgcatatc ccagcgctgg ctggcaaggt
721 cctacgcttc caaaaggctt tcctgaccca gctggatgag ctgctaactg agcacaggat
781 gacctgggac ccagcccagc ccccccgaga cctgactgag gccttcctgg cagagatgga
841 gaaggccaag gggaaccctg agagcagctt caatgatgag aacctgtgca tagtggtggc
901 tgacctgttc tctgccggga tggtgaccac ctcgaccacg ctggcctggg gcctcctgct
961 catgatccta catccggatg tgcagcgccg tgtccaacag gagatcgacg acgtgatagg
1021 gcaggtgcgg cgaccagaga tgggtgacca ggctcacatg ccctacacca ctgccgtgat
1081 tcatgaggtg cagcgctttg gggacatcgt ccccctgggt gtgacccata tgacatcccg
1141 tgacatcgaa gtacagggct tccgcatccc taagggaacg acactcatca ccaacctgtc
1201 atcggtgctg aaggatgagg ccgtctggga gaagcccttc cgcttccacc ccgaacactt
1261 cctggatgcc cagggccact ttgtgaagcc ggaggccttc ctgcctttct cagcaggccg
1321 ccgtgcatgc ctcggggagc ccctggcccg catggagctc ttcctcttct tcacctccct
1381 gctgcagcac ttcagcttct cggtgcccac tggacagccc cggcccagcc accatggtgt
1441 ctttgctttc ctggtgaccc catcccccta tgagctttgt gctgtgcccc gctagaatgg
1501 ggtacctagt cccca
//