LOCUS BC067109 4535 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens dihydropyrimidinase-like 2, mRNA (cDNA clone MGC:70846
IMAGE:3870039), complete cds.
ACCESSION BC067109
VERSION BC067109.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4535)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4535)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: c Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 50811906.
FEATURES Location/Qualifiers
source 1..4535
/db_xref="H-InvDB:HIT000262444"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:70846 IMAGE:3870039"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4535
/gene="DPYSL2"
/gene_synonym="CRMP2"
/gene_synonym="DHPRP2"
/gene_synonym="DRP-2"
/gene_synonym="DRP2"
/db_xref="GeneID:1808"
/db_xref="HGNC:HGNC:3014"
/db_xref="MIM:602463"
CDS 316..2034
/gene="DPYSL2"
/gene_synonym="CRMP2"
/gene_synonym="DHPRP2"
/gene_synonym="DRP-2"
/gene_synonym="DRP2"
/codon_start=1
/product="dihydropyrimidinase-like 2"
/protein_id="AAH67109.1"
/db_xref="GeneID:1808"
/db_xref="HGNC:HGNC:3014"
/db_xref="MIM:602463"
/translation="MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQ
IGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTT
MIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHG
VNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGIT
GPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYG
EPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHC
TFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVF
NLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQG
KIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSV
TPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRA
NITSLG"
BASE COUNT 1110 a 1100 c 1051 g 1274 t
ORIGIN
1 ggcttttatt gctgtagttt atttccaccc ccttccctcc tgtttctctc tctccttctc
61 tctctctctc tctctctctt ttttttccgc cctagctggg gctgtgttgg aggagaggaa
121 gaaagagaga cagaggattg cattcatccg ttacgttctt gaaatttcct aatagcaaga
181 ccagcgaagc ggttgcaccc ttttcaatct tgcaaaggaa aaaaacaaaa caaaacaaaa
241 aaaacccaag tccccttccc ggcagttttt gccttaaagc tgccctcttg aaattaattt
301 tttcccagga gagagatgtc ttatcagggg aagaaaaata ttccacgcat cacgagcgat
361 cgtcttctga tcaaaggagg taaaattgtt aatgatgacc agtcgttcta tgcagacata
421 tacatggaag atgggttgat caagcaaata ggagaaaatc tgattgtgcc aggaggagtg
481 aagaccatcg aggcccactc ccggatggtg atccccggag gaattgacgt ccacactcgt
541 ttccagatgc ctgatcaggg aatgacgtct gctgatgatt tcttccaagg aaccaaggcg
601 gccctggctg ggggaaccac tatgatcatt gaccacgttg ttcctgagcc tgggacaagc
661 ctgctcgctg cctttgacca gtggagggaa tgggccgaca gcaagtcctg ctgtgactac
721 tctctgcatg tggacatcag cgagtggcat aagggcatcc aggaggagat ggaagcgctt
781 gtgaaggatc acggggtaaa ttccttcctc gtgtacatgg ctttcaaaga tcgcttccag
841 ctaacggatt gccagattta tgaagtactg agtgtgatcc gggatattgg cgccatagcc
901 caagtccacg cagaaaatgg cgacatcatt gcagaggagc agcagaggat cctggatctg
961 ggcatcacgg gccccgaggg acatgtgctg agccgacctg aggaggtcga ggccgaagcc
1021 gtgaatcgtg ccatcaccat cgccaaccag accaactgcc cgctgtatat caccaaggtg
1081 atgagcaaaa gctctgctga ggtcatcgcc caggcacgga agaagggaac tgtggtgtat
1141 ggcgagccca tcactgccag cttgggaacg gacggctccc attactggag caagaactgg
1201 gccaaggctg ctgcctttgt cacctcccca cccttgagcc ctgatccaac cactccagac
1261 tttctcaact ccttgctgtc ctgtggagac ctccaggtca cgggcagtgc ccattgcacg
1321 tttaacactg cccagaaggc tgtaggaaag gacaacttca ccctgattcc ggagggcacc
1381 aatggcactg aggagcggat gtccgtcatc tgggacaagg ctgtggtcac tgggaagatg
1441 gatgagaacc agtttgtggc tgtgaccagc accaatgcag ccaaagtctt caacctttac
1501 ccccggaaag gccgcattgc tgtgggatcc gatgccgacc tggtcatctg ggaccccgac
1561 agcgttaaaa ccatctctgc caagacacac aacagctctc tcgagtacaa catctttgaa
1621 ggcatggagt gccgcggctc cccactggta gtcatcagcc aggggaagat tgtcctggag
1681 gacggcaccc tgcatgtcac cgaaggctct ggacgctaca ttccccggaa gcccttccct
1741 gattttgttt acaagcgtat caaggcaagg agcaggctgg ctgagctgag aggggttcct
1801 cgtggcctgt atgacggacc cgtgtgtgaa gtgtctgtga cgcccaagac agtcactcca
1861 gcctcctcgg ccaagacgtc tcctgccaag cagcaggccc cacctgtccg gaacctgcac
1921 cagtctggat tcagtttgtc tggtgctcag attgatgaca acattccccg ccgcaccacc
1981 cagcgtatcg tggcgccccc cggtggccgt gccaacatca ccagcctggg ctagagctcc
2041 tgggctgtgc cgtccactgg ggactgggga tgggacacct gaggacattc tgagacttct
2101 ttcttccttc cttttttttt ttttgttttt ttttttaaga gcctgtgata gttactgtgg
2161 agcagccagt tcatggggtc ccccttgggg ccccacaccc cgtctctcac caagagttac
2221 tgattttgct catccacttc cctacacatc tatgggtatc acacccaaga ctacccacca
2281 agctcataca gggaaccaca cccaacactt agacatgcga acaagcagcc cccagcgagg
2341 gtctccttcg ccttcaacct cctagtgtct gttagcatct tccttttcat ggggggaggg
2401 aagataaagt gaattgccca gagctgcctt tttcttttct ttttaaaaat tttaagaagt
2461 tttctttgtg gggctgggga ggggccgggg tcagggagag tctttttttt tttttttttt
2521 ttaaatacta aattggaaca tttaattcca tattaataca aggggtttga actggacatc
2581 ctaatgatgc aattacgtca tcacccagct gattccgggt ggttggcaaa ctcatcgtgt
2641 ctgtcctgag aggctccaca atgcccaccc gcatcgccat tctgtagtct tcagggtcag
2701 ctgttgataa aggggcaggc ttgcgttatt ggcctagatt ttgctgcaga ttaaatcctt
2761 tgaggattct cttctctttt accatttttc tgcgtgctct cactctctct ttctctctct
2821 agctttttaa ttcatgaata ttttcgtgtc tgtctctctc tctctctgtg tttcctccag
2881 cccttgtctc ggagacggtg ttttcctccc ttgccccatt atcttttcac ctcccaggtc
2941 taccatttca tggtggtcgt tgggtccgcc taaaggattt gagcgtttgc cattgcaagc
3001 atagtgctgt gtcatcctgg tccatgtagg actggtgcta accacctgcc atcatgagga
3061 tgtgtgctag agtgtgggac cctggccaag tgcaggaatg ggccatgccg tctcacccac
3121 agtatcacat gtggaaccgc agacagggcc cagaagcttt agaggtatga ggctgcagaa
3181 ccggagagat tttcctctgt gcagtgctct ctggctaaag tcacggtcaa acctaaacac
3241 cgagcctcat taacccaagt gaaccaacca aagtcaccag ttcagaagtg ctaagctaat
3301 aggagtctga cccgagggcc tgctgcttcc tggttaagta tcttttgaga ttctagaaca
3361 catgggagct ttttattttc ggggaaaaac cgtatttttt tcttgtccaa ttatttctaa
3421 agacacacta catagaaaga ggccctataa actcaaaaag tcattgggaa acttaaagtc
3481 tattctactt tgcaagagga gaaatgtgtt ttatgaacga tagatcacat cagaactcct
3541 gtggggagga aaccttataa attaaacaca tggccccctt agagaccaca ggcgatgtct
3601 gtctccatcc ttccctctcc ttttctgtca cctttccccc tagctggctc ctttggacct
3661 acccctgtcc ttgctgactt gtgttgcatt gtattccaaa cgtgtttaca ggttctctta
3721 agcaatgttg tatttgcagg cttttctgaa taccaaatct gctttttgta aagcgtaaaa
3781 acatcacaaa gtaggtcatt ccatcaccac ccttgtctct ctacacattt tgcctttggg
3841 gatctggttg gggttttggg ttttttgttg ttgttgttta tttgttattt taaaggtaaa
3901 ttgcactttt aaaaaaataa ttggttgact taatatattt gctttttttc ttacctgcac
3961 ttagaggaaa tttgaacaag ttggaaaaaa acaatttttg tttcaattct aagaaacact
4021 tgcagctcta gtattcactt gagtcttcct gtttttcctg taccgggtca tggtaatttt
4081 tggttgtttt ggttgttttc ttaaaaaaca agttaaaacc tgacgatttc tgcaggctgt
4141 gtaagcatgt ttacctgttg gcttgctttg tgtgtctgtt aaatgaatgt catatgtaaa
4201 tgctaaaata aatcgacagt gtctcagaac tgaataactg cagtgacttg atgctctaaa
4261 acagtgtagg atttaagaat agatggtttt taatcctgga aattgtgatt gtgacccatg
4321 agtggaggaa ctttcagttc taaagctgat aaagtgtgta gccagaagag tacttttttt
4381 tttgtaacca ctgtcttgat ggcaaaataa ttatggtaaa aaacaagtct cgtgtttatt
4441 attccttaag aactctgtgt tatattacca tggaacgcct aataaagcaa aatgtggttg
4501 tttcaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//