LOCUS BC065561 3009 bp mRNA linear HUM 02-JUL-2005
DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10-like,
mRNA (cDNA clone IMAGE:6144815), partial cds.
ACCESSION BC065561
VERSION BC065561.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3009)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3009)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: j Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33354274.
FEATURES Location/Qualifiers
source 1..3009
/db_xref="H-InvDB:HIT000261967"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6144815"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..3009
/gene="ARHGEF10L"
/gene_synonym="FLJ10521"
/db_xref="GeneID:55160"
CDS <1..2501
/gene="ARHGEF10L"
/gene_synonym="FLJ10521"
/codon_start=3
/product="ARHGEF10L protein"
/protein_id="AAH65561.1"
/db_xref="GeneID:55160"
/translation="VCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSL
QLALTELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLT
ETVYGDRGQLIKSKERRVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWNTALPQ
VQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGPPRLFQELQDLQKDLAV
VEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPD
KSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFWCP
ILACCIPAFSSRALSLQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQV
EIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICLG
LQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGG
VLWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEA
VSVTHMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIATRTTFLLPGQKHLCVTSL
LICQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVATSILAPD
ILRSDQEEAEGPRAEEDKPDGQAHEPMPDSHVGRELTRKKGILLQYRLRSTAHLPGPL
LSMREPAPADGAALEHSEEDGSIYEMADDPDVWVRSRPCARDAHRKEICSVAIISGGQ
GYRNFGSALGSSGRQAPCGETDSTLLIWQVPLML"
BASE COUNT 617 a 922 c 912 g 558 t
ORIGIN
1 aggtgtgcag cccagaccgt gtcaccctct acgggctgat ggtcaagccc atccagaggt
61 tcccacagtt catactcctg cttcaggaca tgctgaagaa cacccccagg ggccatccgg
121 acaggctgtc gctgcagctg gccctcacag agctggagac gctggctgag aagctgaacg
181 agcagaagcg gctggctgac caggtggctg agatccagca gctgaccaag agcgtcagtg
241 accgcagcag cctcaacaag ctgttgacct caggccagcg gcagctgctc ctgtgtgaga
301 cgttgacgga gaccgtgtac ggtgaccgcg ggcagctaat taagtccaag gagcgtcggg
361 tcttcctgct caacgacatg cttgtctgtg ccaacatcaa cttcaagggc cagctggaga
421 tcagcagcct ggtgcccctg gggcccaagt atgtggtgaa gtggaacacg gcgctgcccc
481 aggtgcaggt ggtggaggtg ggccaggacg gtggcaccta tgacaaggac aatgtgctca
541 tccagcactc aggcgccaag aaggcctctg cctcagggca ggctcagaat aaggtgtacc
601 tcggcccccc acgcctcttc caggagctgc aggacctgca gaaggacctg gccgtggtgg
661 agcagatcac gcttctcatc agcacgctgc acggcaccta ccagaacctg aacatgactg
721 tggctcaaga ctggtgcctg gccctgcaga ggctgatgcg ggtgaaggag gaagagatcc
781 actcggccaa caagtgccgt ctcaggctcc tgcttcctgg gaaacccgac aagtccggcc
841 gccccattag cttcatggtg gttttcatca cccccaaccc cctgagcaag atttcctggg
901 tcaacaggtt acatttggcc aaaatcggac tccgggagga gaaccagcca ggctggctat
961 gcccggatga ggacaagaag agcaaagccc cattctggtg cccgatcctg gcctgctgca
1021 tccctgcctt ctcctcccgg gcactcagcc tgcagcttgg ggccctggtc cacagtcctg
1081 tcaactgtcc cctgctgggt ttctcagcag tcagcacctc ccttccacag ggctacctct
1141 gggtcggggg cggacaggaa ggcgcagggg gccaggtgga aatcttttcc ttgaaccggc
1201 cctcgccccg caccgtcaag tccttcccac tggcagcccc tgtgctctgc atggagtata
1261 tcccggagct ggaggaggag gcggagagca gagacgagag cccgacagtt gctgacccct
1321 cggccacggt gcatccaacc atctgcctcg ggctccagga tggcagcatc ctcctctaca
1381 gcagtgtgga cactggcacc cagtgcctgg tgagctgcag gagcccaggt ctgcagcctg
1441 tgctctgcct gcgacacagc cccttccacc tgctcgctgg cctgcaggat gggacccttg
1501 ctgcttaccc tcggaccagc ggaggtgtcc tgtgggacct ggagagccct cccgtgtgcc
1561 tgactgtggg gcccgggcct gtccgcaccc tgttgagcct ggaggatgcc gtgtgggcca
1621 gctgtgggcc ccgggtcact gtcctggaag ccaccaccct gcagcctcag caaagcttcg
1681 aggcgcacca ggacgaggca gtgagcgtga cacacatggt gaaggcgggc agcggcgtct
1741 ggatggcctt ctcctccggc acctccatcc gcctcttcca cactgagacc ctggagcatc
1801 tgcaagagat caacatcgcc accaggacca ccttcctcct gccaggccag aagcacttgt
1861 gtgtcaccag cctcctgatc tgccagggtc tgctctgggt gggcactgac cagggtgtca
1921 tcgtcctgct gcccgtgcct cggctggaag gcatccccaa gatcacaggg aaaggcatgg
1981 tctcactcaa tgggcactgt gggcctgtgg ccttcctggc tgtggctacc agcatcctgg
2041 cccctgacat cctgcggagt gaccaggagg aggctgaggg gccccgggct gaggaggaca
2101 agccagacgg gcaggcacac gagcccatgc ccgacagcca cgtgggccga gagctgaccc
2161 gcaagaaggg catcctcttg cagtaccgcc tgcgctccac cgcacacctc ccgggcccgc
2221 tgctctccat gcgggagccg gcgcctgctg atggcgcagc tttggagcac agcgaggagg
2281 acggctccat ttacgagatg gccgacgacc ccgacgtctg ggtgcgcagc cggccctgcg
2341 cccgcgacgc ccaccgcaag gagatttgct ctgtggccat catctccggc gggcagggct
2401 accgcaactt tggcagcgct ctgggcagca gtgggaggca ggccccgtgt ggggagacgg
2461 acagcaccct cctcatctgg caggtgccct tgatgctata gcgcctcccc tctcccctca
2521 gagggcacag ctgcaggcct gaccaaggcc acgcccggct ctcgtgctct aggacctgca
2581 cgggacttgt ggatgggcct ggactctcca gaaactactt gggccagagc aaaggaaaac
2641 ctcttgtttt aaaaaaattt ttttcagagt gttttgggga ggagttttag ggcttgggga
2701 gagggaggac acatctggag gaaatggcct tctttttaaa agcaaaaaac acaaaacctc
2761 acaactgcct ggcaagccca gtatcacttg tttgggccct agcgggactc caaggcagcc
2821 acacgcccct cctggaaggg tgtgtgcgtg tgagtgtgtg cgagtgtgtg ggctggtgtg
2881 tgaatatcta taaataagta tatatggtgt atattatatg tgtataaata aagtctgtac
2941 atattggagc tctgggagat gctggaataa aagacaagag ttacatctgg aaaaaaaaaa
3001 aaaaaaaaa
//