LOCUS BC065511 1865 bp mRNA linear HUM 27-JAN-2004
DEFINITION Homo sapiens serum/glucocorticoid regulated kinase 2, mRNA (cDNA
clone MGC:74468 IMAGE:5730271), complete cds.
ACCESSION BC065511
VERSION BC065511.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1865)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1865)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (26-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Invitrogen
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 139 Row: h Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 25168260.
FEATURES Location/Qualifiers
source 1..1865
/db_xref="H-InvDB:HIT000261918"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74468 IMAGE:5730271"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_124"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1865
/gene="SGK2"
/gene_synonym="dJ138B7.2"
/gene_synonym="H-SGK2"
/db_xref="GeneID:10110"
/db_xref="MIM:607589"
CDS 105..1208
/gene="SGK2"
/gene_synonym="dJ138B7.2"
/gene_synonym="H-SGK2"
/codon_start=1
/product="SGK2 protein"
/protein_id="AAH65511.1"
/db_xref="GeneID:10110"
/db_xref="MIM:607589"
/translation="MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKG
NYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYS
FQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDL
KPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWW
CLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQR
LGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKS
IGCTPDTVASSSGASSAFLGFSYAPEDDDILDC"
misc_feature 204..980
/gene="SGK2"
/gene_synonym="dJ138B7.2"
/gene_synonym="H-SGK2"
/note="S_TKc; Region: Serine/Threonine protein kinases,
catalytic domain. Phosphotransferases of the serine or
threonine-specific kinase subfamily. The enzymatic
activity of these protein kinases is controlled by
phosphorylation of specific residues in the activation
segment of the catalytic domain, sometimes combined with
reversible conformational changes in the C-terminal
autoregulatory tail"
/db_xref="CDD:cd00180"
misc_feature 987..1106
/gene="SGK2"
/gene_synonym="dJ138B7.2"
/gene_synonym="H-SGK2"
/note="S_TK_X; Region: Extension to Ser/Thr-type protein
kinases"
/db_xref="CDD:smart00133"
BASE COUNT 503 a 479 c 466 g 417 t
ORIGIN
1 acagagagag gctctcttgt ccactgcctg tcttcggttc caactgctgg ttctgctaga
61 ggcctctcct cagactcgca gagctgcctg atcattgcta cagaatgaac tctagcccag
121 ctgggacccc aagtccacag ccctccaggg ccaatgggaa catcaacctg gggccttcag
181 ccaacccaaa tgcccagccc acggacttcg acttcctcaa agtcatcggc aaagggaact
241 acgggaaggt cctactggcc aagcgcaagt ctgatggggc gttctatgca gtgaaggtac
301 tacagaaaaa gtccatctta aagaagaaag agcagagcca catcatggca gagcgcagtg
361 tgcttctgaa gaacgtgcgg caccccttcc tcgtgggcct gcgctactcc ttccagacac
421 ctgagaagct ctacttcgtg ctcgactatg tcaacggggg agagctcttc ttccacctgc
481 agcgggagcg ccggttcctg gagccccggg ccaggttcta cgctgctgag gtggccagcg
541 ccattggcta cctgcactcc ctcaacatca tttacaggga tctgaaacca gagaacattc
601 tcttggactg ccagggacac gtggtgctga cggattttgg cctctgcaag gaaggtgtag
661 agcctgaaga caccacatcc acattctgtg gtacccctga gtacttggca cctgaagtgc
721 ttcggaaaga gccttatgat cgagcagtgg actggtggtg cttgggggca gtcctctacg
781 agatgctcca tggcctgccg cccttctaca gccaagatgt atcccagatg tatgagaaca
841 ttctgcacca gccgctacag atccccggag gccggacagt ggccgcctgt gacctcctgc
901 aaagccttct ccacaaggac cagaggcagc ggctgggctc caaagcagac tttcttgaga
961 ttaagaacca tgtattcttc agccccataa actgggatga cctgtaccac aagaggctaa
1021 ctccaccctt caacccaaat gtgacaggac ctgctgactt gaagcatttt gacccagagt
1081 tcacccagga agctgtgtcc aagtccattg gctgtacccc tgacactgtg gccagcagct
1141 ctggggcctc aagtgcattc ctgggatttt cttatgcgcc agaggatgat gacatcttgg
1201 attgctagaa gagaaggacc tgtgaaacta ctgaggccag ctggtattag taaggaatta
1261 ccttcagctg ctaggaagag cgactcaaac taacaatggc ttcaacgaga agcaggttta
1321 ttttttccag cacataaaag aaaaataatg tttcggagtc caggactggc aggacaggtc
1381 atcagatact cagaggctgt atctctgccc tgccaacctt gacaaatggc ttccaatgtt
1441 aggtttgcta caagatggtt actggagctc tagctgccta ttttgtgttt agggaaggga
1501 aaatggagga aaggggagaa gagcaaaggg cgcttttaaa gagctttccc aaaagctcca
1561 cccaatgact tctgcttcca tctcactaac cacccacccc tacctggaat ggaggctggg
1621 agatgtggct tatttgctgg gtacgtgact atccctaata acaaaggggt tctgacacta
1681 agacattagg ggagaatgtt gggtaggcag ccagcactct tttaccagag ggcctcctgg
1741 tgtttggatt ttgatctcaa tgtgtaaaat gacagagatg taacaagctc atagggtatc
1801 aatatctctt attgttctaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1861 aaaaa
//