LOCUS BC065298 3281 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens RAB5B, member RAS oncogene family, mRNA (cDNA clone
MGC:75139 IMAGE:6146668), complete cds.
ACCESSION BC065298
VERSION BC065298.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3281)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3281)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: j Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33943097.
FEATURES Location/Qualifiers
source 1..3281
/db_xref="H-InvDB:HIT000261860"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75139 IMAGE:6146668"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3281
/gene="RAB5B"
/db_xref="GeneID:5869"
/db_xref="HGNC:HGNC:9784"
/db_xref="MIM:179514"
CDS 114..761
/gene="RAB5B"
/codon_start=1
/product="RAB5B, member RAS oncogene family"
/protein_id="AAH65298.2"
/db_xref="GeneID:5869"
/db_xref="HGNC:HGNC:9784"
/db_xref="MIM:179514"
/translation="MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQ
FHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDI
TNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFM
ETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN"
BASE COUNT 796 a 845 c 729 g 911 t
ORIGIN
1 acgggggaga cggagcccca ggagtgttga agcctggaaa tcccctcccc ttccccctcc
61 cccctttaca gtatccccct ccctccaccc tttcccattc tgataatctg gccatgacta
121 gcagaagcac agctaggccc aatgggcaac cccaggccag caaaatttgc cagttcaaat
181 tggtcctgct gggagaatct gcagtgggaa agtcaagcct ggtattacgt tttgtcaaag
241 ggcagttcca tgagtaccag gagagcacca ttggagcggc cttcctcacc cagtccgttt
301 gtctagatga cacaacagtg aagtttgaga tctgggacac agctgggcag gagcgatatc
361 acagcttagc ccccatgtac tacaggggtg cccaagctgc aatcgtggtt tacgacatta
421 ctaatcagga aacctttgcc cgagcaaaga catgggtgaa ggaactacag cgacaggcca
481 gtcctagcat cgttattgcc ctggcaggga acaaagctga cctggccaac aaacgtatgg
541 tggagtatga agaggcccag gcatatgcag atgacaacag cttattgttc atggagactt
601 cagccaagac agctatgaac gtgaatgatc tcttcctggc aatagctaag aagttgccaa
661 agagtgaacc ccagaatctg ggaggtgcag caggccgaag ccggggtgtg gatctccatg
721 aacagtccca gcagaacaag agccagtgtt gtagcaactg agggggtggc tagcagcaaa
781 caagtatgga gctagcacaa gagctaagaa ataacctcca tccctacccc tcagcacaca
841 acccctacgg taacagcaca ctgagccctg gctcccaagg gctgcctcct gacagctccg
901 tcatggcact ttttaacgct tcagcaacaa acaccaggca gctgttgcca ctggcctcct
961 accccctact ctggggcttg ggggtcaact ccccccagga cttaccttcc aaaacaaact
1021 ttcttcactt tgtattatag gtacaagaca gcgacttacg tatcttttct cctcctccct
1081 agtgttcctc cccatttttt cagaaaacac ttctgactcc tgtcccttcc ccttctgctt
1141 ttggtcagtc cctgttcttg agcctctttt ctcctctccc caggatgcag aaagtggtga
1201 acccaggaac tgaggaagga ggtttccagt tcatttacat taagggccct gggggagaat
1261 aaagctcaga gcaggaggga gtaaggaaac atttcctttt tgtttttatt tggttggagt
1321 ttctcatatt tgaaaacact gcggtatcca tgatttggcc ttgtggaggg tgttcctagg
1381 tagaggtgag aatggggagg caagatctca ggcaccaggc aggaggtgcc ttgtaagcta
1441 actgggcgga ggtggaggtg cagtgtcaac tgtggctctg taactcttca aaggcccagt
1501 ttcccctcac gcagcctctt aggtagcgtt tcccctaatc gtgggggttg gaccccagag
1561 tcttccaaag aattttcact ggttgcctgc atctttggct ctgctgtgat ctgattggag
1621 gagggacagt ttctggtacc catcctctga tttatacata tgcatttttt cccctctggc
1681 ctttagatgg cctcagcccc agccaccata tacccctgca gtttgcactt taattgatgg
1741 tagttcagtt ggggtacttg ttttatggaa gttttgattg atttacttgc cctcccacct
1801 tctttttaat tcaatgaaat ctgaggttaa tgcgaggttc gaggagaggt tatagataaa
1861 actaccagtg gcagctactc aagtcctatc tccactgtta gcttcctcca actctaatta
1921 ttaacctata ttcttgccaa gctaactatt gactataggt ttgcctttcc tggagaatta
1981 attgagcaat tgaggagtgt ctcaggatag cacaggccaa ggtaggggag taaaaaggag
2041 gtcaggcaaa agggaggagt tttctgtcct ttcccaggtt tcacactcaa tttgatatcc
2101 attaccatgt cttttctact tccttgtaaa taggtatgat ctttattccc actgtacagt
2161 ctgttctatc ctctgcctcc catcaggccc tgtttctttg ttcctttgtt aatatcttga
2221 atttagtccc tccatcctta atccccccat ccctccccat catgcaacca gtggtttaat
2281 ccatgtacca ataggggcta gtaccacaga ggcctcctgt ggtgccctcg tatcatacca
2341 cctgttcctg tggagaggga atgaccggca ctgaaggtac cttacaactg gctcatatta
2401 tcagaggacc ttggtccttt ctaaatctct agtctctctt catatccttc atcaggtgtt
2461 ttaagatgtc tctgagaagc catcaaggca aaagagaact ttaagttcct tgttccagcc
2521 cggagttttg ggaaagaaag aaaggaaagg tcacagtgac ctaggattgg aaccttcctg
2581 cccttttggc ttgcagactg ccttctatcc cagaacagct gagaaatcta tgaagctgag
2641 attctgaagg acccagctta ggttcttcca cttaggcctc aattcccttc cttttccagg
2701 ggcagcctta gttcccatgg ccctgaaaca cacacatttc ccccttcctt tcccagaagc
2761 cactggcccc ccatagcacc cagtgcatcc tttttacaag tggaagaact aggatggctt
2821 tccaaagtct tctagaaatg aagttctttc tctgtgcagc tttccccctt ggagcaggag
2881 tgaagatgtt tcattatctt gggcctggga aaccacttcc ccaggcttct ccctcccccc
2941 acccccatag gaacaggatt tggccttagc ttctgggcct atcggctgcc ttccctctac
3001 ttcctaccac ctcttctgcc ttcctttgag ctctgttggg cttggggatc ttagttttct
3061 tttgtttatt tcccagctca tttttttctt ctggtcagtt tttttaaggg ggggtgttgt
3121 ggttttttgt ttttgttttg cttctgagaa agcatttgcc tttcttcctc tcccaacata
3181 acaatcgtgg taacagaatg cgactgctga tttaccgatg tatttaatgt aagtaaaaaa
3241 aggaaaaaaa gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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