LOCUS BC065227 5167 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens signal transducer and activator of transcription 5B,
mRNA (cDNA clone MGC:74606 IMAGE:5553426), complete cds.
ACCESSION BC065227
VERSION BC065227.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5167)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5167)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 139 Row: b Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42519913.
FEATURES Location/Qualifiers
source 1..5167
/db_xref="H-InvDB:HIT000261790"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74606 IMAGE:5553426"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..5167
/gene="STAT5B"
/gene_synonym="STAT5"
/db_xref="GeneID:6777"
/db_xref="HGNC:HGNC:11367"
/db_xref="MIM:604260"
CDS 170..2533
/gene="STAT5B"
/gene_synonym="STAT5"
/codon_start=1
/product="signal transducer and activator of transcription
5B"
/protein_id="AAH65227.1"
/db_xref="GeneID:6777"
/db_xref="HGNC:HGNC:11367"
/db_xref="MIM:604260"
/translation="MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWD
SVDLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCP
MELVRCIRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTEN
ELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQRE
AQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQ
SWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFII
EKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDY
SGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSV
GGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAEPGRVPFAVPDKVLWPQLC
EALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGR
NYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEI
GGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVYSKY
YTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGGGSATYMDQAPSPAVCPQAHY
NMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQWIPHAQS"
BASE COUNT 1304 a 1262 c 1378 g 1223 t
ORIGIN
1 ggcgggagga gagtcggcgg ccggagccgt caccccgggc ggggacccag cgcaggcaac
61 tccgcgcggc ggcccggccg agggagggag cgagcgggcg ggcgggcaag ccagacagct
121 gggccggagc agccgcgggc gcccgagggg ccgagcgaga ttgtaaacca tggctgtgtg
181 gatacaagct cagcagctcc aaggagaagc ccttcatcag atgcaagcgt tatatggcca
241 gcattttccc attgaggtgc ggcattattt atcccagtgg attgaaagcc aagcatggga
301 ctcagtagat cttgataatc cacaggagaa cattaaggcc acccagctcc tggagggcct
361 ggtgcaggag ctgcagaaga aggcagagca ccaggtgggg gaagatgggt ttttactgaa
421 gatcaagctg gggcactatg ccacacagct ccagaacacg tatgaccgct gccccatgga
481 gctggtccgc tgcatccgcc atatattgta caatgaacag aggttggtcc gagaagccaa
541 caatggtagc tctccagctg gaagccttgc tgatgccatg tcccagaaac acctccagat
601 caaccagacg tttgaggagc tgcgactggt cacgcaggac acagagaatg agttaaaaaa
661 gctgcagcag actcaggagt acttcatcat ccagtaccag gagagcctga ggatccaagc
721 tcagtttggc ccgctggccc agctgagccc ccaggagcgt ctgagccggg agacggccct
781 ccagcagaag caggtgtctc tggaggcctg gttgcagcgt gaggcacaga cactgcagca
841 gtaccgcgtg gagctggccg agaagcacca gaagaccctg cagctgctgc ggaagcagca
901 gaccatcatc ctggatgacg agctgatcca gtggaagcgg cggcagcagc tggccgggaa
961 cggcgggccc cccgagggca gcctggacgt gctacagtcc tggtgtgaga agttggccga
1021 gatcatctgg cagaaccggc agcagatccg cagggctgag cacctctgcc agcagctgcc
1081 catccccggc ccagtggagg agatgctggc cgaggtcaac gccaccatca cggacattat
1141 ctcagccctg gtgaccagca cgttcatcat tgagaagcag cctcctcagg tcctgaagac
1201 ccagaccaag tttgcagcca ctgtgcgcct gctggtgggc gggaagctga acgtgcacat
1261 gaaccccccc caggtgaagg ccaccatcat cagtgagcag caggccaagt ctctgctcaa
1321 gaacgagaac acccgcaatg attacagtgg cgagatcttg aacaactgct gcgtcatgga
1381 gtaccaccaa gccacaggca cccttagtgc ccacttcagg aatatgtccc tgaaacgaat
1441 taagaggtca gaccgtcgtg gggcagagtc ggtgacagaa gaaaaattta caatcctgtt
1501 tgaatcccag ttcagtgttg gtggaaatga gctggttttt caagtcaaga ccctgtccct
1561 gccagtggtg gtgatcgttc atggcagcca ggacaacaat gcgacggcca ctgttctctg
1621 ggacaatgct tttgcagagc ctggcagggt gccatttgcc gtgcctgaca aagtgctgtg
1681 gccacagctg tgtgaggcgc tcaacatgaa attcaaggcc gaagtgcaga gcaaccgggg
1741 cctgaccaag gagaacctcg tgttcctggc gcagaaactg ttcaacaaca gcagcagcca
1801 cctggaggac tacagtggcc tgtctgtgtc ctggtcccag ttcaacaggg agaatttacc
1861 aggacggaat tacactttct ggcaatggtt tgacggtgtg atggaagtgt taaaaaaaca
1921 tctcaagcct cattggaatg atggggccat tttggggttt gtaaacaagc aacaggccca
1981 tgacctactc attaacaagc cagatgggac cttcctcctg agattcagtg actcagaaat
2041 tggcggcatc accattgctt ggaagtttga ttctcaggaa agaatgtttt ggaatctgat
2101 gccttttacc accagagact tctccattcg gtccctagcc gaccgcttgg gagacttgaa
2161 ttaccttatc tacgtgtttc ctgatcggcc aaaagatgaa gtatactcca aatactacac
2221 accagttccc tgcgagtctg ctactgctaa agctgttgat ggatacgtga agccacagat
2281 caagcaagtg gtccctgagt ttgtgaacgc atctgcagat gccgggggcg gcagcgccac
2341 gtacatggac caggccccct ccccagctgt gtgtccccag gctcactata acatgtaccc
2401 acagaaccct gactcagtcc ttgacaccga tggggacttc gatctggagg acacaatgga
2461 cgtagcgcgg cgtgtggagg agctcctggg ccggccaatg gacagtcagt ggatcccgca
2521 cgcacaatcg tgaccccgcg acctctccat cttcagcttc ttcatcctca ccagaggaat
2581 cactcttgtg gatgttttaa ttccatgaat cgcttctctt ttgaaacaat actcataatg
2641 tgaagtgtta atactagttg tgaccttagt gtttctgtgc atggtggcac cagcgaaggg
2701 agtgcgagta tgtgtttgtg tgtgtgtgtg tgtgtgtgtg tgcgtgtttg cacgttatgg
2761 tgtttctccc tctcactgtc tgagagttta gttgtagcag aggggccaca gacagaagct
2821 gtggtggttt ttactttgtg caaaaaggca gtgagtttcg tgaagcctgg aagttggcca
2881 tgtgtcttaa gagtggctgg actttgacat gtggctgttt gaataagaga aggacaaagg
2941 gaggagaaag cacatgtgct ccagtgagtc ttcgtcactc tgtctgccaa gcaattgata
3001 tataaccgtg attgtctctg cttttcttct gaaatgtaga taactgcttt ttgacaaaga
3061 gagccttccc tctcccccac ccctgtgttc ttgggtagga atgggaaaag gggcaaccta
3121 caaagattgt tggggcaagg gaagtcacaa gctttcggat gggcggtggc ttttcacaaa
3181 acatttagct catcttattc tctctttgtc ctctctcccc tcctgcccgc ccgcaccctg
3241 gaattgccac tcagttcctc tgggtgtgca catatgtttg gagaaataga ggagagaaaa
3301 gagggccacg taactgagag cttacagtgc caatgccgtt tgtgttctgg ccagagtgga
3361 gtgcgcagcc ctgactccca ggcgctgaga ttgttgcctg gttacccagg aagctgctgt
3421 tccggctgcc cagcctttct ctgagccagc ggatgcacag tccgtggcct tcttcaggct
3481 tattgatgat gctttttgca aatgttgaat catggttctg tttctaagtt ggatcttttt
3541 tgttttctcc ttgccaccct aatttgacat caaaattctc tcttgtgcat tgggccctgg
3601 gtcattcaaa cccaggtcac ctcattcccc ttctctgttc acacctaatg tcttgaagag
3661 taggtagcag cagtgtgggc tgaacctagg ccagcttgct tagcgggtca ccctgctgtg
3721 aagtcctggc aggtgttggt aatgtgtgga aatgcagtca gcaagtttgc tggggagttt
3781 gataaaagta taaaacaaaa caaaaaaagc ctcggtataa ttttgttcca cgacttcttc
3841 tgtagcttta caccagaagg aaggaatggg ctacagcagg tagtggagga agaggggggt
3901 gagcaggtgt attaaaatag cttacgggta aggcctaaaa ggtcacccct cggccccctc
3961 tccaaaagaa gggcatgggc acccccagga gaggatggcc ccaaaaacct tatttttata
4021 catgagagta aataaacata ttttttttac aaaaataact tctgaattta tcagtgtttt
4081 gccgttaaaa atattcctct atagtaaatt atttattgga agatgacttt tttaaagctg
4141 ccgtttgcct tggcttggtt tcatacactg atttattttt ctatgccagg cagtagagtc
4201 tctctgcctc tgaggagcag gctacccgca tcccactcag cccctcccta cccctcaaga
4261 tttgatgaaa attccaacca tgaggatggg tgcatcgggg aagggtgaga aggagagcct
4321 gcctgctcag ggatccaggc tcgtagagtc actccctgcc cgtctcccag agatgcttca
4381 ccagcacctg cctctgagac ctcgctctct gttccagcaa ccctggttgg ggggtcagac
4441 ttgatacact ttcaggttgg gagtggaccc accccagggc ctgctgagga cagagcagcc
4501 aggccgtcct ggctcacttt gcagttggca ctgggttggg gaggaagaga gctgatgagt
4561 gtggcttccc tgagctgggg tttccctgct tgtccagttg tgagctgtcc tcggtgttac
4621 cgaggctgtg cctagagagt ggagattttt gatgaaaggt gtgctcgctc tctgcgttct
4681 atcttctctc tcctccttgt tcctgcaaac cacaagataa aggtagtggt gtgtctcgac
4741 cccatcagcc tctcacccac tcccagacac acacaagtcc tcaaaagttt cagctccgtg
4801 tgtgagatgt gcaggttttt tctagggggt agggggagac taaaatcgaa tataacttaa
4861 aatgaaagta tactttttat aatttttctt tttaaaactt ggtgaaatta tttcagatac
4921 atattttagt gtcaaggcag attagttatt tagccaccaa aaaaaagtat tgtgtacaat
4981 ttggggcctc aaatttgact ctgcctcaaa aaaaagaaat atatcctatg cagagttaca
5041 gtcacaaagt tgtgtatttt atgttacaat aaagccttcc tctgaaggga aaaaaaaaaa
5101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
5161 aaaaaaa
//