LOCUS BC065209 1777 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens deoxyribonuclease II, lysosomal, mRNA (cDNA clone
MGC:75162 IMAGE:5502061), complete cds.
ACCESSION BC065209
VERSION BC065209.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1777)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1777)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 135 Row: p Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 58331228.
FEATURES Location/Qualifiers
source 1..1777
/db_xref="H-InvDB:HIT000261772"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75162 IMAGE:5502061"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1777
/gene="DNASE2"
/gene_synonym="DNASE2A"
/db_xref="GeneID:1777"
/db_xref="HGNC:HGNC:2960"
/db_xref="MIM:126350"
CDS 92..1174
/gene="DNASE2"
/gene_synonym="DNASE2A"
/codon_start=1
/product="deoxyribonuclease II, lysosomal"
/protein_id="AAH65209.1"
/db_xref="GeneID:1777"
/db_xref="HGNC:HGNC:2960"
/db_xref="MIM:126350"
/translation="MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEA
AQRGLQYKYLDESSGGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQP
SKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCV
SFPFAQFSKMGKQLTYTYPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLT
SQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNV
NQIAFPGPAGPSFNSTEDHSKWCVSPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALW
KAFQPLVKNYQPCNGMARKPSRAYKI"
BASE COUNT 428 a 505 c 503 g 341 t
ORIGIN
1 gaaaggcgcc aggtgccagt cctggcctct gatgtaaccc agcgccccgc agtcccgaca
61 cagattcctg gatctcagcc ccatagcagc tatgatcccg ctgctgctgg cagcgctgct
121 gtgcgtcccc gccggggccc tgacctgcta cggggactcc gggcagcctg tagactggtt
181 cgtggtctac aagctgccag ctcttagagg gtccggggag gcggcgcaga gagggctgca
241 gtacaagtat ctggacgaga gctccggagg ctggcgggac ggcagggcac tcatcaacag
301 cccggagggg gccgtgggcc gaagcctgca gccgctgtac cggagcaaca ccagccagct
361 cgccttcctg ctctacaatg accaaccgcc tcaacccagc aaggctcagg actcttccat
421 gcgtgggcac acgaagggtg tcctgctcct tgaccacgat gggggcttct ggctggtcca
481 cagtgtacct aacttccctc caccggcctc ctctgctgca tacagctggc ctcatagcgc
541 ctgtacctac gggcagaccc tgctctgtgt gtcttttccc ttcgctcagt tctcgaagat
601 gggcaagcag ctgacctaca cctacccctg ggtctataac taccagctgg aagggatctt
661 tgcccaggaa ttccccgact tggagaatgt ggtcaagggc caccacgtta gccaagaacc
721 ctggaacagc agcatcacac tcacatccca ggccggggct gttttccaga gctttgccaa
781 gttcagcaaa tttggagatg acctgtactc cggctggttg gcagcagccc ttggtaccaa
841 cctgcaggtc cagttctggc acaaaactgt aggcatcctg ccctctaact gctcggatat
901 ctggcaggtt ctgaatgtga accagatagc tttccctgga ccagccggcc caagcttcaa
961 cagcacagag gaccactcca aatggtgcgt gtccccaaaa gggccctgga cctgcgtggg
1021 tgacatgaat cggaaccagg gagaggagca acggggtggg ggcacactgt gtgcccagct
1081 gccagccctc tggaaagcct tccagccgct ggtgaagaac taccagccct gtaatggcat
1141 ggccaggaag cccagcagag cttataagat ctaaccctta tggccaggtg cagtggctca
1201 cgtatgtaat cccagcactt tgggaagcca aggagggagg atcacttgaa ctcaggaatt
1261 cgagaccagc ctgggctaca tagtgagacc acatctctac tagaacttaa aaaaagttag
1321 ccaggcacgg tgataaatgc ctgtagtccc agccactgaa gccagaggat cgattgaacc
1381 agggagatca tggtcacagt gaactatgat tacgccaacc tgggtcacat agcaagactc
1441 tgtttcaaaa aaaaaggggg ggcgggggac gggtgggtgc agtggctcac atctgtaacc
1501 ccagcacttt gggaggctga gatgggcaga tcacttgagg tcaggagttc gagaccagcc
1561 tggccaacat ggtgaaaccc catatccatt aaaaatattt aaaaattagc cagacatggt
1621 ggcacgcgtc tgtggtccta gctcctcggg aggctgaggc aggagaatcg cttgaactcg
1681 ggaggcagag gttgtcatga gctgagctaa caccacggca cttcagcctg ggtgacagaa
1741 tgagactctg tgtcaaaaaa ataaaaaaaa aaaaaaa
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