LOCUS BC065195 2270 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens patatin-like phospholipase domain containing 3, mRNA
(cDNA clone MGC:75176 IMAGE:5243623), complete cds.
ACCESSION BC065195
VERSION BC065195.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2270)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2270)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 135 Row: m Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 17196625.
FEATURES Location/Qualifiers
source 1..2270
/db_xref="H-InvDB:HIT000261758"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75176 IMAGE:5243623"
/tissue_type="Brain, fetal, whole pooled"
/clone_lib="NIH_MGC_121"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2270
/gene="PNPLA3"
/gene_synonym="iPLA(2)epsilon"
/db_xref="GeneID:80339"
/db_xref="HGNC:HGNC:18590"
/db_xref="MIM:609567"
CDS 102..1547
/gene="PNPLA3"
/gene_synonym="iPLA(2)epsilon"
/codon_start=1
/product="patatin-like phospholipase domain containing 3"
/protein_id="AAH65195.1"
/db_xref="GeneID:80339"
/db_xref="HGNC:HGNC:18590"
/db_xref="MIM:609567"
/translation="MYDAERGWSLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLF
GASAGALHCVGVLSGIPLEQTLQVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLGKCL
PANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFMPFYSGLIPPSFR
GVRYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNFLHVDITKLSLRLCTGN
LYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICNRPQPGLKSSSEGMDPEVAMP
SWANMSLDSSPESAALAVRLEGDELLDHLRLSILPWDESILDTLSPRLATALSEEMKD
KGGYMSKICNLLPIRIMSYVMLPCTLPVESAIAIVQRLVTWLPDMPDDVLWLQWVTSQ
VFTRVLMCLLPASRSQMPVSSQQASPCTPEQDWPCWTPCSPEGCPAETKAEATPRSIL
RSSLNFFLGNKVPAGAEGLSTFPSFSLEKSL"
BASE COUNT 515 a 614 c 604 g 537 t
ORIGIN
1 cgcttgcggg cgccgggcgg agctgctgcg gatcaggacc cgagccgatt cccgatcccg
61 acccagatcc taacccgcgc ccccgccccg ccgccgccgc catgtacgac gcagagcgcg
121 gctggagctt gtccttcgcg ggctgcggct tcctgggctt ctaccacgtc ggggcgaccc
181 gctgcctgag cgagcacgcc ccgcacctcc tccgcgacgc gcgcatgttg ttcggcgctt
241 cggccggggc gttgcactgc gtcggcgtcc tctccggtat cccgctggag cagactctgc
301 aggtcctctc agatcttgtg cggaaggcca ggagtcggaa cattggcatc ttccatccat
361 ccttcaactt aagcaagttc ctccgacagg gtctcggcaa atgcctcccg gccaatgtcc
421 accagctcat ctccggcaaa ataggcatct ctcttaccag agtgtctgat ggggaaaacg
481 ttctggtgtc tgactttcgg tccaaagacg aagtcgtgga tgccttggta tgttcctgct
541 tcatgccttt ctacagtggc cttatccctc cttccttcag aggcgtgcga tatgtggatg
601 gaggagtgag tgacaacgta cccttcattg atgccaaaac aaccatcacc gtgtccccct
661 tctatgggga gtacgacatc tgccctaaag tcaagtccac gaactttctt catgtggaca
721 tcaccaagct cagtctacgc ctctgcacag ggaacctcta ccttctctcg agagcttttg
781 tccccccgga tctcaaggtg ctgggagaga tatgccttcg aggatatttg gatgcattca
841 ggttcttgga agagaagggc atctgcaaca ggccccagcc aggcctgaag tcatcctcag
901 aagggatgga tcctgaggtc gccatgccca gctgggcaaa catgagtctg gattcttccc
961 cggagtcggc tgccttggct gtgaggctgg agggagatga gctgctagac cacctgcgtc
1021 tcagcatcct gccctgggat gagagcatcc tggacaccct ctcgcccagg ctcgctacag
1081 cactgagtga agaaatgaaa gacaaaggtg gatacatgag caagatttgc aacttgctac
1141 ccattaggat aatgtcttat gtaatgctgc cctgtaccct gcctgtggaa tctgccattg
1201 cgattgtcca gagactggtg acatggcttc cagatatgcc cgacgatgtc ctgtggttgc
1261 agtgggtgac ctcacaggtg ttcactcgag tgctgatgtg tctgctcccc gcctccaggt
1321 cccaaatgcc agtgagcagc caacaggcct ccccatgcac acctgagcag gactggccct
1381 gctggactcc ctgctccccc gagggctgtc cagcagagac caaagcagag gccaccccgc
1441 ggtccatcct caggtccagc ctgaacttct tcttgggcaa taaagtacct gctggtgctg
1501 aggggctctc cacctttccc agtttttcac tagagaagag tctgtgagtc acttgaggag
1561 gcgagtctag cagattcttt cagaggtgct aaagtttccc atctttgtgc agctacctcc
1621 gcattgctgt gtagtgaccc ctgcctgtga cgtggaggat cccagcctct gagctgagtt
1681 ggttttatga aaagctagga agcaaccttt cgcctgtgca gcggtccagc acttaactct
1741 aatacatcag catgcgttaa ttcagctggt tgggaaatga caccaggaag cccagtgcag
1801 agggtccctt actgactgtt tcgtggccct attaatggtc agactgttcc agcatgaggt
1861 tcttagaatg acaggtgttt ggatgggtgg gggccttgtg atggggggta ggctggccca
1921 tgtgtgatct tgtggggtgg agggaagaga atagcatgat cccacttccc catgctgtgg
1981 gaaggggtgc agttcgtccc caagaacgac actgcctgtc aggtggtctg caaagatgat
2041 aaccttgact actaaaaacg tctccatggc gggggtaaca agatgataat ctacttaatt
2101 ttagaacacc tttttcacct aactaaaata atgtttaaag agttttgtat aaaaatgtaa
2161 ggaagcgttg ttacctgttg aattttgtat tatgtgaatc agtgagatgt tagtagaata
2221 agccttaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//