LOCUS BC064994 3534 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens lethal giant larvae homolog 2 (Drosophila), mRNA (cDNA
clone MGC:75113 IMAGE:5575350), complete cds.
ACCESSION BC064994
VERSION BC064994.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3534)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3534)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 139 Row: d Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62739160.
FEATURES Location/Qualifiers
source 1..3534
/db_xref="H-InvDB:HIT000261699"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75113 IMAGE:5575350"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3534
/gene="LLGL2"
/gene_synonym="HGL"
/gene_synonym="LGL2"
/db_xref="GeneID:3993"
/db_xref="HGNC:HGNC:6629"
CDS 128..3190
/gene="LLGL2"
/gene_synonym="HGL"
/gene_synonym="LGL2"
/codon_start=1
/product="lethal giant larvae homolog 2 (Drosophila)"
/protein_id="AAH64994.1"
/db_xref="GeneID:3993"
/db_xref="HGNC:HGNC:6629"
/translation="MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSL
RILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSL
KVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPA
FRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDL
QGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYG
PFPCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIG
FTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHH
VSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFW
DASGVCLRLLYKLSTVRVFLTDTDPNENLSAQGEDEWPPLRKVGSFDPYSDDPRLGIQ
KIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAA
RSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFV
KCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAK
AERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGG
TIYAFSLRVPPAERRMDESVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHD
LSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRA
EDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLIS
PSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQP
GLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNGGAE"
BASE COUNT 650 a 1131 c 1122 g 631 t
ORIGIN
1 gtgggcaggc gcggcggagc gagcggggcc ggcggcgggc gccgagggac gccgagggac
61 gccgaggcct cgggcggggg ctggcccggg gttccaggtc tccagtgggg gctgcagact
121 aagcaaaatg aggcggttcc tgaggccagg gcatgaccct gtgcgggaga ggctcaagcg
181 ggacctgttc cagtttaaca agacggtgga gcatggcttc ccgcaccagc ccagcgccct
241 cggctacagc ccgtccctgc gcatcctggc catcggcacc cgttctggag ccatcaagct
301 ctacggagcc ccaggcgtgg agttcatggg gctgcaccag gagaacaacg ctgtgacgca
361 gatccacctc ctgcccggcc agtgccagct ggtcaccctg ctggatgaca acagcctgca
421 cctttggagc ctgaaggtca agggcggggc atcggagctg caggaggatg agagcttcac
481 actgcgtgga cccccagggg ctgcccccag tgccacacag atcaccgtgg tcctgccaca
541 ttcctcctgc gagctgctct acctgggcac cgagagtggc aacgtgtttg tggtgcagct
601 gccagctttt cgtgcgctgg aggaccggac catcagctcg gacgcggtgc tgcagcggtt
661 gccagaggag gcccgccacc ggcgtgtgtt cgagatggtg gaggcactgc aggagcaccc
721 tcgagacccc aaccagatcc tgatcggcta cagccgaggc ctcgttgtca tctgggacct
781 acagggcagc cgcgtgctct accacttcct cagcagccag caactggaga acatctggtg
841 gcagcgggac ggccgcctgc tcgtcagctg tcactctgac ggcagctact gccagtggcc
901 cgtgtccagc gaagcccagc aaccagagcc cctccgcagc ctcgtgcctt acggtccctt
961 tccttgcaaa gcgattacca gaatcctctg gctgaccact aggcaggggt tgcccttcac
1021 catcttccag ggtggcatgc cacgggccag ctacggggac cgccactgca tctcagtgat
1081 ccacgatggc cagcagacgg ccttcgactt cacctcccgt gtcatcggct tcactgtcct
1141 cacagaggca gaccctgcag ccacctttga cgacccctat gccctggtgg tgctggctga
1201 ggaggagctg gtggtgattg acctgcagac agcaggctgg ccaccggtcc agctgcccta
1261 cctggcttct ctgcactgtt ccgccatcac ctgctctcac cacgtctcca acatcccgct
1321 gaagctgtgg gagcggatca ttgccgccgg cagccggcag aacgcacact tctccaccat
1381 ggagtggcca attgatggtg gcaccagcct gaccccagcc ccaccccaga gggacctgct
1441 gctcacaggg cacgaggacg gcacggtgcg gttctgggat gcctcgggtg tctgcctgcg
1501 gctgctctac aaactcagca ctgtgcgcgt gttcctcacc gacacggacc ccaacgagaa
1561 cctcagtgcc cagggcgagg acgagtggcc cccactccgc aaggtgggct cctttgaccc
1621 ctacagtgat gacccccggc tgggcatcca gaagatcttc ctctgcaagt acagcggcta
1681 cctggctgtg gcaggcacgg cagggcaggt gctggtactg gaactgaatg acgaggcagc
1741 ggagcaggct gtggagcagg tggaggccga cctgctgcag gaccaagagg gctaccgctg
1801 gaaggggcac gagcgcctgg cagcccgctc agggcccgtg cgctttgagc ctggctttca
1861 gcccttcgtg ttggtgcagt gtcagccccc ggctgtggtc acctccttgg ccctgcactc
1921 tgagtggcgg ctcgtggcct tcggcaccag ccatggcttt ggcctctttg accaccagca
1981 gcggcggcag gtctttgtta agtgcacact gcaccccagt gaccagctgg ccttggaggg
2041 cccactctcc cgcgtcaagt ccctcaagaa gtccttgcgt cagtcattcc gccggatgcg
2101 tcggagccgg gtgtccagcc ggaagcggca cccagctggc cccccaggag aggcacagga
2161 ggggagtgcc aaggctgagc ggccaggcct ccagaacatg gagctggcgc ctgtgcagcg
2221 caagatcgag gctcgctcgg cagaggactc cttcacaggc ttcgtccgga ccctgtactt
2281 tgctgacacc tacctgaagg acagctcccg gcactgcccc tcgctgtggg ctggcaccaa
2341 tgggggcacc atctatgcct tctccctgcg tgtgcctccc gccgagcgga gaatggatga
2401 gtctgtgcgg gcagagcagg ccaaggagat ccagctgatg caccgggcgc cggtggtggg
2461 catcctggtg ctcgacggac acagcgtacc ccttcctgag cccctcgaag tggcccatga
2521 tctgtcgaag agccctgaca tgcagggaag ccaccagctg ctcgtcgtat cagaggagca
2581 gttcaaggtg ttcacgctgc ccaaggtgag tgccaagctg aagttgaagc tgacggccct
2641 ggagggctca agagtgcggc gggtcagcgt ggcccacttc ggcagtcgtc gagccgagga
2701 ctacggggag caccacctgg cagtccttac caacctgggc gacatccagg tggtctcgct
2761 gcccctgctc aagccccagg tgcgctacag ctgcatccgc cgggaggacg tcagtggcat
2821 cgcctcctgc gtcttcacca aatatggcca aggcttctac ctgatctcac cctcggagtt
2881 tgagcgcttc tctctctcca ccaagtggct ggtggagccc cggtgtctgg tggattcagc
2941 agaaaccaag aaccaccgcc ctggtaacgg tgcgggcccc aagaaggccc cgagccgagc
3001 caggaactca gggactcaga gtgatggcga ggagaagcag cccggcctgg tgatggagcg
3061 cgctctgctc agtgatgaga gagtcctgaa ggaaatccag agcacactgg agggagaccg
3121 cgggagcggc aactggcgtt cacatcgagc ggccgtgggg tgcagcctca gcaatggcgg
3181 agcagagtga gtggctgagc gtccaggctg cgcgatgagc acacactact actgatggcc
3241 tttcgggggt ccctgcccca gccggagagg ccggtgcaca gggccccgcc aggggctggg
3301 ggcatcccgg cttccacaat gcagctgctc tgggcctcgg gagaggagag accccagtcc
3361 cctgggctgc ccttcccggg cctcgtctgt ctgggtcctt tggtcaatgt tgcacagttt
3421 ttattgctcc catccctttt tgtagtgggc tgggttttaa gttataaatg ttaactgcct
3481 ctgggtgaaa aagtttttaa taaacaccta ttacctctta aaaaaaaaaa aaaa
//