LOCUS BC064916 3496 bp mRNA linear HUM 06-OCT-2006
DEFINITION Homo sapiens Smg-6 homolog, nonsense mediated mRNA decay factor (C.
elegans), mRNA (cDNA clone IMAGE:6070108), complete cds.
ACCESSION BC064916
VERSION BC064916.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3496)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3496)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: g Column: 11
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..3496
/db_xref="H-InvDB:HIT000261624"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6070108"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3496
/gene="SMG6"
/gene_synonym="EST1A"
/gene_synonym="KIAA0732"
/gene_synonym="SMG-6"
/db_xref="GeneID:23293"
/db_xref="HGNC:HGNC:17809"
CDS 296..1831
/gene="SMG6"
/gene_synonym="EST1A"
/gene_synonym="KIAA0732"
/gene_synonym="SMG-6"
/codon_start=1
/product="SMG6 protein"
/protein_id="AAH64916.1"
/db_xref="GeneID:23293"
/db_xref="HGNC:HGNC:17809"
/translation="METFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHN
SQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDI
KVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNIL
TAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCK
RVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVI
EDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE
IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYA
RVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILS
CCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWA
QVG"
BASE COUNT 768 a 1025 c 942 g 761 t
ORIGIN
1 ggacccagat acccgtcaga atttccaggc cttggtttgg tctagacatt ttagaagatg
61 ttaacagcaa taattgtaaa agactttgag tggcacgcat ggtgaacaga aagtactaga
121 tcctgaagag gggggaaagg catttctgtg ctcttcctgg taaagtgttt gaaaatgaac
181 attcagaaga aaacctaaag cacctgaaat gcacagggga cgagaatgag agctgaacaa
241 aaggttcatc ctcagttttc tccatgccca tgggaagctg tttacccgga ttgggatgga
301 gacattccct gcagtggctg agaaggtcct caaggagttc caggtgttac tgcagcacag
361 cccctctccc attggaagta cccgcatgct gcagcttatg accatcaata tgtttgcagt
421 acacaactcc cagctgaaag actgcttctc ggaggagtgc cgctctgtga tccaggaaca
481 agccgcagct ctgggcttgg ccatgttttc tctactggtc cgccgctgca cctgcttact
541 taaggagtcc gccaaagctc agctgtcctc tcctgaggac caggatgacc aagacgacat
601 caaggtgtct tcctttgtcc cggacctgaa ggagctgctc cccagtgtca aagtctggtc
661 agattggatg ctcggctacc cggacacctg gaatcctcct cccacatccc tggatctgcc
721 ctcgcatgtt gctgtggatg tatggtcgac gctggctgat ttctgtaaca tactgactgc
781 agtgaatcag tctgaggtgc cactgtacaa ggacccggat gatgacctca cccttcttat
841 cctggaagag gatcggcttc tctcgggctt tgtccccttg ctggctgccc ctcaggaccc
901 ctgctacgtg gagaaaacct cggataaggt tattgcagct gactgcaaaa gggtcacagt
961 gctgaagtat tttctggaag ccctttgtgg acaagaagag cctctgctgg cattcaaggg
1021 tggaaagtat gtgtcagtgg cacccgtccc agacaccatg ggaaaggaaa tgggaagcca
1081 agagggaaca cgactggaag atgaggagga ggatgtggtg attgaagact ttgaggaaga
1141 ttcagaggct gaaggcagcg gaggcgagga tgacatcagg gagcttcggg ccaagaagct
1201 ggctctggcc aggaagatag ctgagcagca gcgtcgccag gaaaagatcc aggctgtcct
1261 ggaggaccac agtcagatga ggcagatgga gctcgaaatc agacctttgt tcctcgtacc
1321 agacaccaac ggcttcattg accacctggc cagtctggcg cggctgctgg agagcaggaa
1381 gtacatcctg gtggtgcccc tcatcgtgat caatgagctg gacggcctgg ccaaggggca
1441 ggagacagac caccgggctg ggggctacgc ccgtgtggta caagagaagg cccgcaagtc
1501 catcgagttc ctcgagcagc gattcgagag tcgggactct tgcctgcgag ccctgaccag
1561 ccgtggcaat gaactcgaat ccatcgcctt ccgcagtgag gacatcactg gccagctggg
1621 taacaacgat gatctcatcc tgtcctgctg cctccactac tgcaaagaca aggctaagga
1681 cttcatgccc gccagcaaag aggagccaat ccggctactg cgggaggtgg tgctgttgac
1741 ggatgaccgg aacctgcgtg tgaaggcgct cacaaggaat gttcctgtac gggacatccc
1801 agccttcctc acgtgggccc aggtgggctg agggagccac actggggccc ccccccccgt
1861 ggaaccgttc ctgaaaggcc accaggcacc cagtgtagca cggaagatgc ccacgtgcct
1921 gagccaccaa tccacccaga caataaacca tcctcttcca acccacgcca cggccatgct
1981 gtgggggacc tgctcctcac agagcccctc ccaaggatcg ggcggaagct gctgggaccc
2041 tcctgggctg ccaggattta gcagggaggt ggctggctac agcaacagca gctgggcaag
2101 ccagataggc cgcccatgct ctcagccttt ctccctcccc cgtctcattc caaggctgag
2161 ggagggcctt ctcgcctggg gacgcagcca ctttctccag tggagacagg gcaggggttc
2221 agagtttccg tcagatgcag tgaaatcaca gttccctttc atcttcagaa cctctgtcgt
2281 gaatgtgttc aagaggcttt ggttaagtca ggaagaagtg cccagggtgt gtgtccccag
2341 tctccctgag gcctggactc gcccatgaac ccaagtcggc ttctagacag catgtcccta
2401 acagcagccc tgggccccca cctcttctac catccacccc agacttacca cacacccttc
2461 ctgctgctcc tcttcctgcc cttatcaacc tgggtccctc acacttcgcc agttgcgtcc
2521 ccgtggacag tcatgagtct agaggaaagg ggcatctggt ctcaggcccg tgctctcggg
2581 tggcctccac ctgctccctt tctcctcact ggcctttctt tccgtctagc ttcctcttca
2641 ggaaatgtcc tgactctcct cagctccccc ttcacccctc cttgcccgcc taccctccct
2701 ccagaatagc ccctcaccct tcttcccctt ctagttgatc cttttcacct ccctgatccc
2761 cttcatttct tcaccgcggt tcctcgtcat aggggttctc actctgaact ttccctctct
2821 actacccatg gcaggaacct agtacaggtc tcccacccag ggccttccac cctcggctcc
2881 tgtgctggga gaaacttcca ggcgtggaca gcccagcctg aggcattcca gtgctggggc
2941 accgtcgcct aacctggttt ctagctttgc cctcactccc cggaaaaact gacactgaca
3001 caggggccct ttccttgccc ctttagctgg tacctcagtg gggaggcttc cttaccaaga
3061 atgagttcct gaaacccagg gccagagaca aggacaactt aggggaagac ggggttttcg
3121 gtggagccag gggcaaatct taatgggacc agtgggggat accccagagc ccatggcctg
3181 actgcacagc ctgcctggag gatgggtgcg cagctctgcc ctccctgagg cccaggacta
3241 tgccagaagc gatggggtac cgtgtagggg agccaaggcc agtagtttgg gggtaggagt
3301 cccctagagt ctcagaagac tgggctcttt ggagtacagg gtccccggcc tctcctttaa
3361 gattctctcc ccagctggaa ggccgatgac tgggtggtcg ggagggagac ccagctctcc
3421 tttctgtccc gtttgcagca ctggttttgt ttccttaata aatttttagt tatgaaacaa
3481 aaaaaaaaaa aaaaaa
//