LOCUS BC064607 1934 bp mRNA linear HUM 24-FEB-2004
DEFINITION Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type
motif 15, mRNA (cDNA clone IMAGE:5553843), partial cds.
ACCESSION BC064607
VERSION BC064607.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1934)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1934)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (22-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 139 Row: b Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8922791.
FEATURES Location/Qualifiers
source 1..1934
/db_xref="H-InvDB:HIT000261526"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5553843"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1934
/gene="NUDT15"
/gene_synonym="FLJ10956"
/gene_synonym="MTH2"
/db_xref="GeneID:55270"
CDS <1..494
/gene="NUDT15"
/gene_synonym="FLJ10956"
/gene_synonym="MTH2"
/codon_start=3
/product="NUDT15 protein"
/protein_id="AAH64607.1"
/db_xref="GeneID:55270"
/translation="TASAQPRGRRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQL
PGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDV
THDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKG
NHL"
misc_feature 84..407
/gene="NUDT15"
/gene_synonym="FLJ10956"
/gene_synonym="MTH2"
/note="NUDIX; Region: NUDIX domain"
/db_xref="CDD:pfam00293"
BASE COUNT 559 a 341 c 434 g 600 t
ORIGIN
1 tgacggccag cgcacagccg cgcgggcggc ggccaggagt cggagtcgga gtcgtggtga
61 ccagctgcaa gcatccgcgt tgcgtcctcc tggggaagag gaaaggctcg gttggagctg
121 gcagtttcca actccctgga ggtcatctgg agttcggtga aacctgggaa gaatgtgctc
181 aaagggaaac ctgggaagaa gcagctcttc acctgaaaaa tgttcacttt gcctcagttg
241 tgaattcttt cattgagaag gagaattacc attatgttac tatattaatg aaaggagaag
301 tggatgtgac tcatgattca gaaccaaaga atgtagagcc tgaaaaaaat gaaagttggg
361 agtgggttcc ttgggaagaa ctacctcccc tggaccagct tttctgggga ctgcgttgtt
421 taaaagaaca aggctatgat ccatttaaag aagatctgaa ccatctggtg ggatacaaag
481 gaaatcatct ctaggtggcc gagaagattt gattttcttt aaaaagacaa gaataaggtc
541 tggttaggga atgaaaaatg tatacatttc ggaacaactc cattttatct aaaaaagttc
601 ttgtgattgc cagtttattt gcagtctctt aatgtatccc ccactctttc agccagtact
661 tgagaaaatt tttctgaaat atgtcattga attgtattcc agacacagaa tacatgataa
721 atactgatat tatgggtaat ctgctttcca tatttaccta tgatatttac tgtgcagttt
781 gtcattacta gcttgcatgg agtaggatgc agtcaaattt gccttagtgt ttctgttcaa
841 atagagacct gaattcaaat attgtagttt aggttcaaac agagtatggc tgttgcaaaa
901 tttaccaaat ttgttgatta cctcttttat taaagaaatg ttggggagag ggtaatatat
961 tgtgacaatt tttgcaactt acagggaata ggacaggtca ttagggtgta tttcccaggt
1021 ttccaattga gaatctaaac caagagaagt gagacaaacc atctaatatc tgtatcatgc
1081 tattaatagg ctgtgatgtt gagtttctca cttactcttt ctgaggtcca gggtccttat
1141 atgaagagat tcatatatat gaagagattc gtctagagca gtggttgtca aagtgtggtc
1201 tgggggggcc tcaagagcct ttcaagggta ttctaggtca aagctgtttt tataacacta
1261 agacatcatt tcactattta tagcttttcc ttttttttat ttgagaagga gtcttgctct
1321 gttgcccaca ttggagtgca gtggcacgat ctcagctcat tgcagcctcc gccacctggg
1381 ttcaagcaat tctcctacct cagcttcccg agtagctggg attataggca cccaccacca
1441 cacctggcta atttttgtat ttttagtgga gacggggttt caccatgttg gccaggctgg
1501 tctggaactc ctgagctcaa gtgatctgcc catctcagcc tcccaaagtg ctgggattac
1561 aggtatgagc cacaacgccc agccatcatt tatctttttc actcattttt tcatgagtat
1621 gcagaggagt tttcaagagg ctatctggtg tgatattgta ataggctgaa tgcaaaagca
1681 gatacaagat tccagctttc gtctgtcatc agacattgaa gagatttgga gaaatgtaaa
1741 gcagcagtac tcttctcact aatttttgtt gtggttagtt agaaaaatgg ttatttttag
1801 tgggttttaa tatgtgaaaa aaataaaatt agctatttgc caaaaatgtt tttatgtgtt
1861 tatatatact tggttcttgt tacttgcaaa tgattaataa aaattttaag aaatttaata
1921 aaaaaaaaaa aaaa
//