LOCUS BC064487 2183 bp mRNA linear HUM 30-MAR-2004
DEFINITION Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:3834928),
partial cds.
ACCESSION BC064487
VERSION BC064487.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2183)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2183)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (22-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 50 Row: b Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14249599.
FEATURES Location/Qualifiers
source 1..2183
/db_xref="H-InvDB:HIT000261407"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3834928"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_9"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2183
/gene="FRAS1"
/gene_synonym="FLJ14927"
/gene_synonym="FLJ22031"
/gene_synonym="KIAA1500"
/db_xref="GeneID:80144"
/db_xref="MIM:607830"
CDS <1..1957
/gene="FRAS1"
/gene_synonym="FLJ14927"
/gene_synonym="FLJ22031"
/gene_synonym="KIAA1500"
/codon_start=2
/product="FRAS1 protein"
/protein_id="AAH64487.1"
/db_xref="GeneID:80144"
/db_xref="MIM:607830"
/translation="CSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQD
ETVVRVPGKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLR
CGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTG
ECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWED
GPCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDH
CDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRH
GQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKG
FYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVC
HNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPA
PSHCTGCKKPEEGLQVEQLSGVGIPSGECLAQCRAHFYLESTGICEACHQSCFRCAGK
SPHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPH
ISLTNGNCRTSCREEQFLNLVGYCAGE"
misc_feature 188..361
/gene="FRAS1"
/gene_synonym="FLJ14927"
/gene_synonym="FLJ22031"
/gene_synonym="KIAA1500"
/note="VWC; Region: von Willebrand factor type C domain.
The high cutoff was used to prevent overlap with
pfam00094"
/db_xref="CDD:pfam00093"
misc_feature 1070..1837
/gene="FRAS1"
/gene_synonym="FLJ14927"
/gene_synonym="FLJ22031"
/gene_synonym="KIAA1500"
/note="VSP; Region: Giardia variant-specific surface
protein"
/db_xref="CDD:pfam03302"
BASE COUNT 476 a 542 c 629 g 536 t
ORIGIN
1 ctgttcctat gaaggccatg tgtttcagga tggggaggac tggcggctga gccggtgtgc
61 caaatgtctg tgtagaaatg gggttgccca gtgcttcaca gctcagtgtc agcctctatt
121 ttgtaaccag gatgagactg tagtccgagt ccctggaaaa tgttgcccgc agtgctctgc
181 aagatcctgc tctgcagctg gccaagtata cgagcatggt gagcagtgga gcgaaaatgc
241 ctgcaccacg tgtatatgtg accggggtga ggtcaggtgt cacaagcagg cctgcctgcc
301 cctgagatgc ggaaagggtc agagcagggc tcggcgtcat gggcaatgct gtgaggaatg
361 tgtgtctcct gccgggagct gctcctatga tggagttgtg cggtaccagg acgaaatgtg
421 gaagggctcg gcctgtgagt tctgcatgtg tgatcatggc caagtgacct gccagactgg
481 agagtgtgcc aaagtggagt gtgcccggga tgaagaatta attcacttag atggaaagtg
541 ttgtcctgaa tgcatttcaa ggaatggtta ttgtgtttat gaagaaactg gagaatttat
601 gtcatcaaat gctagtgaag ttaaacgtat tccagaggga gagaagtggg aagatggccc
661 ttgcaaggtg tgtgagtgcc gaggggctca ggtaacttgc tacgagccct cttgcccacc
721 atgtccagtg ggcacactgg ccttagaggt gaagggacag tgctgtccag actgcacatc
781 agttcattgc catccagatt gtttgacatg ctctcagtct ccagaccact gtgacctctg
841 ccaagatcct accaagttac tgcagaatgg atggtgtgtg cacagctgtg gactgggttt
901 ttaccaagct ggcagtctct gtttagcctg ccagccccag tgctccacgt gtaccagtgg
961 gctggagtgc tcatcctgcc agcctcccct gctgatgcgg cacgggcagt gtgtgcctac
1021 ctgtggggac ggcttctacc aagatcgcca ttcctgtgca gtctgccatg agtcctgtgc
1081 aggttgctgg ggcccaacgg agaagcactg cttggcctgc agagatcccc tccacgtgct
1141 gagagatggc ggctgtgaga gcagctgtgg aaaaggcttc tacaacaggc agggcacctg
1201 tagcgcttgt gaccaatcct gtgacagttg tggccccagt agccccaggt gtcttacctg
1261 tactgagaag acagtgctgc atgatgggaa atgcatgtct gaatgccctg gcgggtacta
1321 tgctgatgcc actggcaggt gcaaagtttg tcataactca tgtgccagct gctctgggcc
1381 cacaccctct cactgtacag cctgcagccc ccccaaggct ctgcgtcaag gccactgtct
1441 gccccgctgt ggagagggtt tctactctga ccacggagtc tgcaaagcct gtcactcctc
1501 ctgcctggct tgtatgggtc ccgcaccctc tcactgtact gggtgtaaga agccagagga
1561 aggactgcaa gtggagcagc tgtctggcgt gggcatcccc tctggcgagt gtctagccca
1621 gtgtagagcc catttttact tggagagcac tggcatatgt gaagcttgcc accagtcctg
1681 tttcagatgt gcagggaaaa gcccacataa ctgcacagac tgtgggcctt cccatgtgct
1741 gttggatggg cagtgcctct cccagtgccc agatggctac tttcaccagg aaggtagttg
1801 cacagagtgt cacccaacct gcaggcagtg tcatgggccg ttggagtctg actgcatctc
1861 ctgttaccct cacatctctc ttaccaatgg taactgcagg accagctgca gggaagagca
1921 gttcctcaac ctcgtgggat actgtgctgg tgagtgaaac tcctgtggac tcctcggaaa
1981 tcactgggca gctgccgggg ctcttcatac caggcttaag ggggctcttt gtcctcagtt
2041 tatgagctct tttataggag acatttgttt catgtctgga aactcatgtt actgcttctc
2101 cttgggcatt tagtaaatac ttgtggattt aaatagaact tctaataata ctcttgcaaa
2161 tcctgaaaaa aaaaaaaaaa aaa
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