LOCUS BC064146 1866 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and
spastic paraplegia), mRNA (cDNA clone MGC:75494 IMAGE:30378779),
complete cds.
ACCESSION BC064146
VERSION BC064146.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1866)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1866)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Michael Brownstein
cDNA Library Preparation: Invitrogen Corp
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: m Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 63055069.
FEATURES Location/Qualifiers
source 1..1866
/db_xref="H-InvDB:HIT000261288"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75494 IMAGE:30378779"
/tissue_type="Testis"
/clone_lib="NIH_MGC_180"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..1866
/gene="OPA3"
/gene_synonym="FLJ22187"
/gene_synonym="MGA3"
/db_xref="GeneID:80207"
/db_xref="HGNC:HGNC:8142"
/db_xref="MIM:606580"
CDS 13..555
/gene="OPA3"
/gene_synonym="FLJ22187"
/gene_synonym="MGA3"
/codon_start=1
/product="optic atrophy 3 (autosomal recessive, with
chorea and spastic paraplegia)"
/protein_id="AAH64146.1"
/db_xref="GeneID:80207"
/db_xref="HGNC:HGNC:8142"
/db_xref="MIM:606580"
/translation="MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLP
PAQLYHWLEMRTKMRIMGFNAAAIKPLNEGAAAELGAELLGEGIIFITACSCLMLEYW
RHQLQQRRKEKERRVAREALRGEVGHLGLALEELQAQVQATSTQLALEELRAQLQEVR
AHLCLRDPPPAPPVAPASEK"
BASE COUNT 363 a 622 c 480 g 401 t
ORIGIN
1 gagaccgcca agatggtggt gggcgcgttc cctatggcga agctgctata cttgggcatc
61 cggcaggtca gcaagccgct tgccaaccgt attaaggagg ccgcccgccg aagcgagttc
121 ttcaagacct atatctgcct cccgccggct caactgtacc actggctgga gatgcggacc
181 aaaatgcgca tcatgggttt caatgccgct gccatcaagc cgctgaacga gggtgcagcc
241 gccgagctgg gcgcggagct gctgggcgag ggcatcatct tcatcaccgc ctgcagctgc
301 ctgatgctgg agtattggcg ccaccagttg cagcagcgcc gcaaggaaaa ggagcgacgt
361 gttgccaggg aggcgctgcg gggcgaggtg ggccacttgg ggctggcgct cgaggagttg
421 caggcgcagg tgcaggcgac gtcgacgcag ctcgccctgg aggagctgcg cgctcagctg
481 caggaggtgc gagcccacct ctgcctccga gacccgccgc ctgcaccccc agttgcgccg
541 gcgtccgaga aataggaggt ctcggggccc tggtcttgga ggtgactgct gtctggactg
601 cgaagtctct gtcttggcct attctccgca ctgtcccatc ctggaccggc ccagctgaca
661 ccacccagtc cttcgggggc gccggagaga tcctgggctg gagctgatcg aacctcccta
721 ctaacctgcc cagtggtacc ttccactggg actctccgcc tcctgcaggt ggaacgttcc
781 aagaaggacc ccgccctatc ccaccccgcc cctgccagcg catttgttga gcactttgga
841 aagacagcgt cttttatcag accccacctc cctaccgcta ggtaggccag caggacgtcc
901 acctcttttg gcaaaacaaa attctgcacc cggatttagc cacctctcat tctgtcaccc
961 gcaccctcac tcacctgagt ggacccttcc cctaggacgc tcatcctttg caccgaacac
1021 cacctacctc ctcctcattg gtacagacca ttgtaaagat gcacaaagtt cctacggact
1081 tcccgacccg cccccttcca tctacctcag tcttaggggg aaaggtgggg gtgaatcctg
1141 gactgcgtta gctccaatga gtcaccaccc tgcggctcct gaccttaatc catcttagta
1201 cctgtcattg acatcctccc ctccctgagt ggatcgatcc aacataaccc ccctcttctt
1261 ccgcctatgg cgcaccccac tggcatggct atgctgggtc ttccagggaa acgcctccca
1321 gcccggcatt ctgtggtctg ttccagcagg acgtggcctt ttgggaggaa aaaccggtct
1381 tgaccagggc tagtccattc tggctttcag gctcagtcac ttggtcacca gtccccagtc
1441 ctggacctac tgctactgtc cttttatccg gtcctccctc gctgtcctct tcagttgcct
1501 ttgctaggga ccggcctgtc cctttactac ctaagtcatc gtcagttcgc ccaacttccc
1561 tccaaatctg cccctcacgg tacgcaggga tcgcccttcc ttcctgcctt tggactggtc
1621 caggtcctcc tccgccctcc ttcacgcaaa ggcctcctcc agggggacta cctgtccctc
1681 agcccagagg tccccctgtc caagcggggt attccaccag gccatatgac ctacccaccc
1741 gacaactgaa gggggcgtgg atgagctctg tgactctgaa tgctacttta taaatcgact
1801 gtcagcgttt tctaattaaa ggagctctgg ggtaaagatc ttaaaaaaaa aaaaaaaaaa
1861 aaaaaa
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