LOCUS BC063824 2807 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
activation protein, zeta polypeptide, mRNA (cDNA clone MGC:74590
IMAGE:6180974), complete cds.
ACCESSION BC063824
VERSION BC063824.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2807)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2807)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: b Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21735624.
FEATURES Location/Qualifiers
source 1..2807
/db_xref="H-InvDB:HIT000261201"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74590 IMAGE:6180974"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2807
/gene="YWHAZ"
/gene_synonym="KCIP-1"
/db_xref="GeneID:7534"
/db_xref="HGNC:HGNC:12855"
/db_xref="MIM:601288"
CDS 78..815
/gene="YWHAZ"
/gene_synonym="KCIP-1"
/codon_start=1
/product="tyrosine 3-monooxygenase/tryptophan
5-monooxygenase activation protein, zeta polypeptide"
/protein_id="AAH63824.2"
/db_xref="GeneID:7534"
/db_xref="HGNC:HGNC:12855"
/db_xref="MIM:601288"
/translation="MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLL
SVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLE
KFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEM
QPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIM
QLLRDNLTLWTSDTQGDEAEAGEGGEN"
BASE COUNT 827 a 544 c 540 g 896 t
ORIGIN
1 gccgccgccg ccgcccagag actgctgagc ccgtccgtcc gccgccacca cccactccgg
61 acacagaaca tccagtcatg gataaaaatg agctggttca gaaggccaaa ctggccgagc
121 aggctgagcg atatgatgac atggcagcct gcatgaagtc tgtaactgag caaggagctg
181 aattatccaa tgaggagagg aatcttctct cagttgctta taaaaatgtt gtaggagccc
241 gtaggtcatc ttggagggtc gtctcaagta ttgaacaaaa gacggaaggt gctgagaaaa
301 aacagcagat ggctcgagaa tacagagaga aaattgagac ggagctaaga gatatctgca
361 atgatgtact gtctcttttg gaaaagttct tgatccccaa tgcttcacaa gcagagagca
421 aagtcttcta tttgaaaatg aaaggagatt actaccgtta cttggctgag gttgccgctg
481 gtgatgacaa gaaagggatt gtcgatcagt cacaacaagc ataccaagaa gcttttgaaa
541 tcagcaaaaa ggaaatgcaa ccaacacatc ctatcagact gggtctggcc cttaacttct
601 ctgtgttcta ttatgagatt ctgaactccc cagagaaagc ctgctctctt gcaaagacag
661 cttttgatga agccattgct gaacttgata cattaagtga agagtcatac aaagacagca
721 cgctaataat gcaattactg agagacaact tgacattgtg gacatcggat acccaaggag
781 acgaagctga agcaggagaa ggaggggaaa attaaccggc cttccaactt ttgtctgcct
841 cattctaaaa tttacacagt agaccatttg tcatccatgc tgtcccacaa atagtttttt
901 gtctacgatt tatgacaggt ttatgttact tctatttgaa tttctatatt tcccatgtgg
961 tttttatgtt taatattagg ggagtagagc cagttaacat ttagggagtt atctgttttc
1021 atcttgaggt ggccaatatg gggatgtgga atttttatac aagttataag tgtttggcat
1081 agtacttttg gtacattgtg gcttcaaaag ggccagtgta aaactgcttc catgtctaag
1141 caaagaaaac tgcctacata ctggtttgtc ctggcgggga ataaaaggga tcattggttc
1201 cagtcacagg tgtagtaatt gtgggtactt taaggtttgg agcacttaca aggctgtggt
1261 agaatcatac cccatggata ccacatatta aaccatgtat atctgtggaa tactcaatgt
1321 gtacaccttt gactacagct gcagaagtgt tcctttagac aaagttgtga cccattttac
1381 tctggataag ggcagaaacg gttcacattc cattatttgt aaagttacct gctgttagct
1441 ttcattattt ttgctacact cattttattt gtatttaaat gttttaggca acctaagaac
1501 aaatgtaaaa gtaaagatgc aggaaaaatg aattgcttgg tattcattac ttcatgtata
1561 tcaagcacag cagtaaaaca aaaacccatg tatttaactt ttttttagga tttttgcttt
1621 tgtgattttt tttttttttt tttgatactt gcctaacatg catgtgctgt aaaaatagtt
1681 aacagggaaa taacttgaga tgatggctag ctttgtttaa tgtcttatga aattttcatg
1741 aacaatccaa gcataattgt taagaacacg tgtattaaat tcatgtaagt ggaataaaag
1801 ttttatgaat ggacttttca actactttct ctacagcttt tcatgtaaat tagtcttggt
1861 tctgaaactt ctctaaagga aattgtacat tttttgaaat ttattcctta ttccctcttg
1921 gcagctaatg ggctcttacc aagtttaaac acaaaattta tcataacaaa aatactacta
1981 atataactac tgtttccatg tcccatgatc ccctctcttc ctccccaccc tgaaaaaaat
2041 gagttcctat tttttctggg agaggggggg attgattaga aaaaaatgta gtgtgttcca
2101 tttaaaattt tggcatatgg cattttctaa cttaggaagc cacaatgttc ttggcccatc
2161 atgacattgg gtagcattaa ctgtaagttt tgtgcttcca aatcactttt tggtttttaa
2221 gaatttcttg atactcttat agcctgcctt caattttgat cctttattct ttctatttgt
2281 caggtgcaca agattacctt cctgttttag ccttctgtct tgtcaccaac cattcttact
2341 tggtggccat gtacttggaa aaaggccgca tgatctttct ggctccactc agtgtctaag
2401 gcaccctgct tcctttgctt gcatcccaca gactatttcc ctcatcctat ttactgcagc
2461 aaatctctcc ttagttgatg agactgtgtt tatctccctt taaaacccta cctatcctga
2521 atggtctgtc attgtctgcc tttaaaatcc ttcctctttc ttcctcctct attctctaaa
2581 taatgatggg gctaagttat acccaaagct cactttacaa aatatttcct cagtactttg
2641 cagaaaacac caaacaaaaa tgccatttta aaaaaggtgt attttttctt ttagaatgta
2701 agctcctcaa gagcagggac aatgttttct gtatgttcta ttgtgcctag tacactgtaa
2761 atgctcaata aatattgatg atgggaggca aaaaaaaaaa aaaaaaa
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