LOCUS BC063611 3502 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens pellino homolog 1 (Drosophila), mRNA (cDNA clone
MGC:70885 IMAGE:4992160), complete cds.
ACCESSION BC063611
VERSION BC063611.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3502)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3502)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: o Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..3502
/db_xref="H-InvDB:HIT000261065"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:70885 IMAGE:4992160"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3502
/gene="PELI1"
/db_xref="GeneID:57162"
CDS 389..1645
/gene="PELI1"
/codon_start=1
/product="PELI1 protein"
/protein_id="AAH63611.1"
/db_xref="GeneID:57162"
/translation="MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALF
KRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQI
GRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDS
SKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSL
RETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEIN
AARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECP
MCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFH
AACPFCAHQLAGEQGYIRLIFQGPLD"
misc_feature 389..1618
/gene="PELI1"
/note="Pellino; Region: Pellino. Pellino is involved in
Toll-like signalling pathways, and associates with the
kinase domain of the Pelle Ser/Thr kinase"
/db_xref="CDD:pfam04710"
BASE COUNT 1012 a 691 c 738 g 1061 t
ORIGIN
1 ggcggaggga ccgtcggggg gcgccgccgc cgcctccact agcagcagcg gcagcagccc
61 tagtcccgcg gtgcggtcga attggtcccc agccctccgg gagcgcacca caaagcagcc
121 ccaacgcctc tccctgcgtc cgcggctcct cagcgctcgg ctccgtggtc aacttcccct
181 cgctgggctc ggctggcggg cgcggagggc agcggcggaa cggcgggctg tctgctcgcg
241 ctccccgcgc acaacacttc accctctcgc ctcgggtctc gggggccgct ctgggatccc
301 ggccaccagc aattgtccgg aaataatgca aaaggtgtcc caaggctcct gaccagtgaa
361 caaagatttg agaaagacag ccaagctcat gttttctcct gatcaagaaa atcatccatc
421 taaagcacca gtaaaatatg gtgaactcat tgtcttaggg tataatgggt ctctcccaaa
481 tggcgataga ggaaggagga aaagtaggtt tgctttgttt aaaagaccta aggcaaatgg
541 ggtgaagccc agcactgtgc atattgcttg tactcctcag gctgcaaagg caataagcaa
601 caaagaccag catagcatat catatacttt gtctcgggcc cagactgtgg tggttgaata
661 tactcatgac agcaacacag atatgtttca gattggccgg tcgactgaaa gccccattga
721 ttttgtagta actgacacgg ttcctggaag tcaaagtaat tctgatacac agtcagtaca
781 aagcactata tcaagatttg cctgcagaat catatgtgaa cggaatcctc cctttacagc
841 acggatttat gctgcaggat ttgactcatc aaaaaacatc tttcttgggg agaaggctgc
901 caaatggaag acatcagatg gacagatgga tggcttgacc actaatggtg ttcttgtgat
961 gcatccacgc aatgggttca cagaagactc caagcctgga atatggagag aaatatcggt
1021 gtgtggaaat gtatttagcc tacgtgaaac cagatcggct cagcagagag gaaaaatggt
1081 ggaaattgaa accaatcagt tacaagatgg ctcgttaatt gacctctgtg gtgcaacatt
1141 gttatggcgt actgcagaag gcctttccca cactcctacc gtgaagcatt tagaagcttt
1201 aagacaggaa atcaatgcag cacgacctca gtgccctgta gggttcaaca cactagcatt
1261 tcctagtatg aagaggaaag acgttgtaga tgaaaaacaa ccatgggtat atctaaactg
1321 cggccatgta catggctatc ataactgggg aaacaaagaa gaacgtgatg gaaaagatcg
1381 tgaatgtcct atgtgtaggt ctgttggtcc ctatgttcct ctgtggcttg gatgtgaagc
1441 tggattttat gtggacgccg gccctccaac ccatgcgttt agcccgtgtg ggcatgtgtg
1501 ttcagaaaag acaactgcct attggtccca gatcccactt cctcatggta ctcatacttt
1561 tcatgcagcc tgtccctttt gtgcacatca gttggctggt gaacaaggct acatcagact
1621 tatttttcaa ggacctctag actaacagac cattgtcttg caggactaca ttataaattt
1681 ataagctaag tgagttgggt tttcgaacct gttgtccacg tcacagtttt tctgctctgg
1741 tcatttgcat taagatgaag aattttttaa aacatttata ataaatagta gcaatttctg
1801 agcaaaaatc tgggaaactc aagcaaagga atttctgaaa gtatcagtct tctgaattct
1861 gagttttgaa aatatatttt gaggagaaaa agacatagtc taatttgatg ccttcctttt
1921 agtgtttttg aatcacctat cctcagtgct gaaattgttt tgtataactg agggtactgt
1981 tggttcaaac tatgttagtt tacagtttgt tgcaaacatt gtaaaataca gcgacatgta
2041 tattaacttt tttctattta tctttattat agaaaatacc ttagaatgtt cttgatagag
2101 tagcatggta acgatggtgt cacacccttg gtgtgaatgg tagcttagtg agcaacctag
2161 ctcaaggatt tgcaaagtta ggaagaagga cgagagagcc tctctcccca ccccaatcta
2221 aatatggaat ttggtaaatt agaatacttt gtaatttgta agaccaaatt catactaatt
2281 acccgcgtga aaggtgtttg tttttaacaa cattgaagat aatcaggaaa gattttttct
2341 taatgtttct ctcgagcgta gtactataac aaaaacttaa tgctaagaaa cattttatat
2401 gctcctttgg atatgcaatt taatctagat tatctatttt tctcccatga taactaatct
2461 gtttttagta tcagcagcat ttggcaagtt tattttttgg atataaactg tggttcatct
2521 gttcactgtt tctagaaaaa aatcattgcc ataagaaaaa gtataaatta gcaagaaagg
2581 agagtgactt gatttgcttt tggaaaaaga aatgcttaat taattattct gtatttggcc
2641 ttattcgggc attaggaaat ctagagatct aaagggttga atgacaatag tgcccccgtt
2701 tttagcagac cagccttaac tctgggtttg aatcctaagg agattgccac agtgagactt
2761 aaggaaatgt ttggttggca gatgagcacc aatgactgca gcgtggagtg acgcactgca
2821 tggtctgttt attctctaat tccaatatgt cttttgcttc cagaagcaag aaaagtttct
2881 tctctcccct ccttcccacc cttttttcaa aggcaccaca agtatagaca gttgcactac
2941 atcaaatctt tttttgacac ttgtagaaac cagtacactt ttagattaga cagtatcttc
3001 ttttaatatt ttgatttgtt ttcctttagt ttgaaaagtt gtataatact taactgactg
3061 tagcaaagtt ttatatgtgg tagcatacct ttaatttatc ctattacaaa actgttctga
3121 attttctttt ggtttttaaa aaacaaaact tgttgcttag aagccatgaa ttattttatt
3181 ttacttcaac tgtcgaaact tccttgtttt aaaaaatgat catttgggtt cactcaggaa
3241 atgcatgtca ggaaacttgt attataagtt tattagttgt gatgtatcag taactgctgt
3301 tacccctttt tcaaagaaat gtaattgatt ttgaagtttt ctagattgtc acatgctttg
3361 tgactaatgc aagaaagcaa gtcctgtgtt gtatttgttc tagtcatttt tattcaggct
3421 atatattgta gcttaatttt tatttgcaat taatttattt aaactaagta aatacttttc
3481 aaaatacaaa aaaaaaaaaa aa
//