LOCUS BC063505 1699 bp mRNA linear HUM 15-FEB-2005
DEFINITION Homo sapiens HECT, UBA and WWE domain containing 1, mRNA (cDNA
clone IMAGE:3451298), partial cds.
ACCESSION BC063505
VERSION BC063505.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1699)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1699)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: a Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22538475.
FEATURES Location/Qualifiers
source 1..1699
/db_xref="H-InvDB:HIT000260964"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3451298"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1699
/gene="HUWE1"
/gene_synonym="5430439H10Rik"
/gene_synonym="dJ339A18.2"
/gene_synonym="FLJ20030"
/gene_synonym="HSPC272"
/gene_synonym="Ib772"
/gene_synonym="UREB1"
/db_xref="GeneID:10075"
CDS <1..1168
/gene="HUWE1"
/gene_synonym="5430439H10Rik"
/gene_synonym="dJ339A18.2"
/gene_synonym="FLJ20030"
/gene_synonym="HSPC272"
/gene_synonym="Ib772"
/gene_synonym="UREB1"
/codon_start=2
/product="HUWE1 protein"
/protein_id="AAH63505.1"
/db_xref="GeneID:10075"
/translation="DYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRRDHVFEDS
YRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDR
VTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDM
ESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKK
EYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDL
KSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGI
QKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA"
BASE COUNT 441 a 412 c 382 g 464 t
ORIGIN
1 agactacatt cgtgtcctcg actttgatgt caagcgcaaa tatttccgcc aagagctgga
61 gcgtttagat gaggggctcc ggaaagaaga catggctgtg catgtccgtc gtgaccatgt
121 gtttgaagac tcctatcgtg agctgcatcg caaatccccc gaagaaatga agaatcgatt
181 gtatatagta tttgaaggag aagaagggca ggatgctggc gggctcctgc gggagtggta
241 tatgatcatc tctcgagaga tgtttaaccc tatgtatgcc ttgttccgta cctcacctgg
301 tgatcgagtc acctacacca tcaatccatc ttcccactgc aaccccaacc acctcagcta
361 cttcaagttt gtcggacgca ttgtggccaa agctgtatat gacaaccgtc ttctggagtg
421 ctactttact cgatcctttt acaaacacat cttgggcaag tcagtcagat atacagatat
481 ggagagtgaa gattaccact tctaccaagg tctggtttat ctgctggaaa atgatgtctc
541 cacactaggc tatgacctca ccttcagcac tgaggtccaa gagtttggag tttgtgaagt
601 tcgtgacctc aaacccaatg gggccaacat cttggtaaca gaggagaata agaaggagta
661 tgtacacctg gtatgccaga tgagaatgac aggagccatc cgcaagcagt tggcggcttt
721 cttagaaggc ttctatgaga tcattccaaa gcgcctcatt tccatcttca ctgagcagga
781 gttagagctg cttatatcag gactgcccac cattgacatc gatgatctga aatccaacac
841 tgaataccac aagtaccagt ccaactctat tcagatccag tggttctgga gagcattgcg
901 ttctttcgat caagctgacc gtgccaagtt cctccagttt gtcacgggta cttccaaggt
961 acccctgcaa ggctttgctg ccctcgaagg catgaatggc attcagaagt ttcagatcca
1021 tcgagatgac aggtccacag atcgcctgcc ttcagctcac acatgtttta atcagctgga
1081 tctgcctgcc tatgagagct ttgagaagct ccgccacatg ctactgttgg ctatccagga
1141 gtgctctgaa ggctttgggc tggcctaata aggccctgcc caactccgtg gggttttttt
1201 taccattgtt ggacctgggg aggggggagt taaaaaaaga accagaaaga aattgtcaaa
1261 aaccaataaa tgaaatccac caactcaccg tgtgtgtccc agctgcccca tcttccccag
1321 cgcatacctg ttcctcttct cattctctcc ccgccgcctg tttcctcacc ttctctcccc
1381 tttccatgcc gtccatgatc cccaccccat gtgttttaaa aaggcagtag cctttgcagg
1441 gacctgtctg tcccaactgt ttgaacagtg tgctcctcag attctgtgtt cagaaggatt
1501 tgctgcattg agacttgaaa cctttggata ggggaaaaaa ttatatatat atatattttt
1561 ttgttctgtt tgcatttctt aatttgtgct tggaatgtgt tgatgtgcac agctaatgat
1621 tcaatgcgag acaagattgg cgtctgtgtt gtggaggttt caaataaaga gcactcttca
1681 taaaaaaaaa aaaaaaaaa
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