LOCUS BC063458 2575 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens MRE11 meiotic recombination 11 homolog A (S.
cerevisiae), mRNA (cDNA clone MGC:74523 IMAGE:5181691), complete
cds.
ACCESSION BC063458
VERSION BC063458.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2575)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2575)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 135 Row: d Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56550105.
FEATURES Location/Qualifiers
source 1..2575
/db_xref="H-InvDB:HIT000260918"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74523 IMAGE:5181691"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2575
/gene="MRE11A"
/gene_synonym="ATLD"
/gene_synonym="HNGS1"
/gene_synonym="MRE11B"
/db_xref="GeneID:4361"
/db_xref="HGNC:HGNC:7230"
/db_xref="MIM:600814"
CDS 98..2224
/gene="MRE11A"
/gene_synonym="ATLD"
/gene_synonym="HNGS1"
/gene_synonym="MRE11B"
/codon_start=1
/product="MRE11 meiotic recombination 11 homolog A (S.
cerevisiae)"
/protein_id="AAH63458.1"
/db_xref="GeneID:4361"
/db_xref="HGNC:HGNC:7230"
/db_xref="MIM:600814"
/translation="MSTADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEIL
RLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFG
FSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVE
KIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQ
NRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIAPTKNEQQLFYISQPGSSVVTSLSP
GEAVKKHVGLLRIKGRKMNMHKIPLHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQS
FCLEKIEEMLENAERERLGNSHQPEKPLVRLRVDYSGGFEPFSVLRFSQKFVDRVANP
KDIIHFFRHREQKEKTGEEINFGKLITKPSEGTTLRVEDLVKQYFQTAEKNVQLSLLT
ERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRETR
QKNTNEEDDEVREAMTRARALRSQSEESASAFSADDLMSIDLAEQMANDSDDSISAAT
NKGRGRGRGRRGGRGQNSASRGGSQRGRADTGLETSTRSRNSKTAVSASRNMSIIDAF
KSTRQQPSRNVTTKNYSEVIEVDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSK
GVDFESSEDDDDDPFMNTSSLRRNRR"
BASE COUNT 926 a 418 c 552 g 679 t
ORIGIN
1 gaatttggaa tcgagtgcat tttctgacat ttgagtacag tacccagggg ttcttggaga
61 agaacctggt cccagaggag cttgactgac cataaaaatg agtactgcag atgcacttga
121 tgatgaaaac acatttaaaa tattagttgc aacagatatt catcttggat ttatggagaa
181 agatgcagtc agaggaaatg atacgtttgt aacactcgat gaaattttaa gacttgccca
241 ggaaaatgaa gtggatttta ttttgttagg tggtgatctt tttcatgaaa ataagccctc
301 aaggaaaaca ttacatacct gcctcgagtt attaagaaaa tattgtatgg gtgatcggcc
361 tgtccagttt gaaattctca gtgatcagtc agtcaacttt ggttttagta agtttccatg
421 ggtgaactat caagatggca acctcaacat ttcaattcca gtgtttagta ttcatggcaa
481 tcatgacgat cccacagggg cagatgcact ttgtgccttg gacattttaa gttgtgctgg
541 atttgtaaat cactttggac gttcaatgtc tgtggagaag atagacatta gtccggtttt
601 gcttcaaaaa ggaagcacaa agattgcgct atatggttta ggatccattc cagatgaaag
661 gctctatcga atgtttgtca ataaaaaagt aacaatgttg agaccaaagg aagatgagaa
721 ctcttggttt aacttatttg tgattcatca gaacaggagt aaacatggaa gtactaactt
781 cattccagaa caatttttgg atgacttcat tgatcttgtt atctggggcc atgaacatga
841 gtgtaaaata gctccaacca aaaatgaaca acagctgttt tatatctcac aacctggaag
901 ctcagtggtt acttctcttt ccccaggaga agctgtaaag aaacatgttg gtttgctgcg
961 tattaaaggg aggaagatga atatgcataa aattcctctt cacacagtgc ggcagttttt
1021 catggaggat attgttctag ctaatcatcc agacattttt aacccagata atcctaaagt
1081 aacccaagcc atacaaagct tctgtttgga gaagattgaa gaaatgcttg aaaatgctga
1141 acgggaacgt ctgggtaatt ctcaccagcc agagaagcct cttgtacgac tgcgagtgga
1201 ctatagtgga ggttttgaac ctttcagtgt tcttcgcttt agccagaaat ttgtggatcg
1261 ggtagctaat ccaaaagaca ttatccattt tttcaggcat agagaacaaa aggaaaaaac
1321 aggagaagag atcaactttg ggaaacttat cacaaagcct tcagaaggaa caactttaag
1381 ggtagaagat cttgtaaaac agtactttca aaccgcagag aagaatgtgc agctctcact
1441 gctaacagaa agagggatgg gtgaagcagt acaagaattt gtggacaagg aggagaaaga
1501 tgccattgag gaattagtga aataccagtt ggaaaaaaca cagcgatttc ttaaagaacg
1561 tcatattgat gccctcgaag acaaaatcga tgaggaggta cgtcgtttca gagaaaccag
1621 acaaaaaaat actaatgaag aagatgatga agtccgtgag gctatgacca gggccagagc
1681 actcagatct cagtcagagg agtctgcttc tgcctttagt gctgatgacc ttatgagtat
1741 agatttagca gaacagatgg ctaatgactc tgatgatagc atctcagcag caaccaacaa
1801 aggaagaggc cgaggaagag gtcgaagagg tggaagaggg cagaattcag catcgagagg
1861 agggtctcaa agaggaagag cagacactgg tctggagact tctacccgta gcaggaactc
1921 aaagactgct gtgtcagcat ctagaaatat gtctattata gatgccttta aatctacaag
1981 acagcagcct tcccgaaatg tcactactaa gaattattca gaggtgattg aggtagatga
2041 atcagatgtg gaagaagaca tttttcctac cacttcaaag acagatcaaa ggtggtccag
2101 cacatcatcc agcaaaatca tgtcccagag tcaagtatcg aaaggggttg attttgaatc
2161 aagtgaggat gatgatgatg atccttttat gaacactagt tctttaagaa gaaatagaag
2221 ataatatatt taatggcact gagaaacatg caagatacag gaaaaatgaa aatgttacaa
2281 gctaagagtt tacagtttaa gattttaagt attgtttcct gagcataact ccataagtaa
2341 gaaatttcta gttcacagac atacaatagc attgattcac cttgtttttt taacctggtt
2401 gttgtagtaa gagctttgtt tcaatatcac tcttgagtaa agattaaaat aaagctacca
2461 ttttacattt ctatttcaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2521 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//