LOCUS BC063431 2358 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hepatitis A virus cellular receptor 2, mRNA (cDNA
clone MGC:74657 IMAGE:5229539), complete cds.
ACCESSION BC063431
VERSION BC063431.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2358)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2358)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 135 Row: l Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 49574533.
FEATURES Location/Qualifiers
source 1..2358
/db_xref="H-InvDB:HIT000260891"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74657 IMAGE:5229539"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2358
/gene="HAVCR2"
/gene_synonym="FLJ14428"
/gene_synonym="KIM-3"
/gene_synonym="Tim-3"
/gene_synonym="TIM3"
/gene_synonym="TIMD3"
/db_xref="GeneID:84868"
/db_xref="HGNC:HGNC:18437"
/db_xref="MIM:606652"
CDS 145..1050
/gene="HAVCR2"
/gene_synonym="FLJ14428"
/gene_synonym="KIM-3"
/gene_synonym="Tim-3"
/gene_synonym="TIM3"
/gene_synonym="TIMD3"
/codon_start=1
/product="hepatitis A virus cellular receptor 2"
/protein_id="AAH63431.1"
/db_xref="GeneID:84868"
/db_xref="HGNC:HGNC:18437"
/db_xref="MIM:606652"
/translation="MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAA
PGNLVPVCWGKGACPVFECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTL
ADSGIYCCRIQIPGIMNDEKFNLKLVIKPAKVTPAPTLQRDFTAAFPRMLTTRGHGPA
ETQTLGSLPDINLTQISTLANELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALI
FGALIFKWYSHSKEKIQNLSLISLANLPPSGLANAVAEGIRSEENIYTIEENVYEVEE
PNEYYCYVSSRQQPSQPLGCRFAMP"
BASE COUNT 629 a 536 c 561 g 632 t
ORIGIN
1 cgggtgtgct gagctagcac tcagtggggg cggctactgc tcatgtgatt gtggagtaga
61 cagttggaag aagtacccag tccatttgga gagttaaaac tgtgcctaac agaggtgtcc
121 tctgactttt cttctgcaag ctccatgttt tcacatcttc cctttgactg tgtcctgctg
181 ctgctgctgc tactacttac aaggtcctca gaagtggaat acagagcgga ggtcggtcag
241 aatgcctatc tgccctgctt ctacacccca gccgccccag ggaacctcgt gcccgtctgc
301 tggggcaaag gagcctgtcc tgtgtttgaa tgtggcaacg tggtgctcag gactgatgaa
361 agggatgtga attattggac atccagatac tggctaaatg gggatttccg caaaggagat
421 gtgtccctga ccatagagaa tgtgactcta gcagacagtg ggatctactg ctgccggatc
481 caaatcccag gcataatgaa tgatgaaaaa tttaacctga agttggtcat caaaccagcc
541 aaggtcaccc ctgcaccgac tctgcagaga gacttcactg cagcctttcc aaggatgctt
601 accaccaggg gacatggccc agcagagaca cagacactgg ggagcctccc tgatataaat
661 ctaacacaaa tatccacatt ggccaatgag ttacgggact ctagattggc caatgactta
721 cgggactctg gagcaaccat cagaataggc atctacatcg gagcagggat ctgtgctggg
781 ctggctctgg ctcttatctt cggcgcttta attttcaaat ggtattctca tagcaaagag
841 aagatacaga atttaagcct catctctttg gccaacctcc ctccctcagg attggcaaat
901 gcagtagcag agggaattcg ctcagaagaa aacatctata ccattgaaga gaacgtatat
961 gaagtggagg agcccaatga gtattattgc tatgtcagca gcaggcagca accctcacaa
1021 cctttgggtt gtcgctttgc aatgccatag atccaaccac cttatttttg agcttggtgt
1081 tttgtctttt tcagaaacta tgagctgtgt cacctgactg gttttggagg ttctgtccac
1141 tgctatggag cagagttttc ccattttcag aagataatga ctcacatggg aattgaactg
1201 ggacctgcac tgaacttaaa caggcatgtc attgcctctg tatttaagcc aacagagtta
1261 cccaacccag agactgttaa tcatggatgt tagagctcaa acgggctttt atatacacta
1321 ggaattcttg acgtggggtc tctggagctc caggaaattc gggcacatca tatgtccatg
1381 aaacttcaga taaactaggg aaaactgggt gctgaggtga aagcataact tttttggcac
1441 agaaagtcta aaggggccac tgattttcaa agagatctgt gatccctttt tgttttttgt
1501 ttttgagatg gagtcttgct ctgttgccca ggctggagtg caatggcaca atctcggctc
1561 actgcaagct ccgcctcctg ggttcaagcg attctcctgc ctcagcctcc tgagtggctg
1621 ggattacagg catgcaccac catgcccagc taatttgttg tatttttagt agagacaggg
1681 tttcaccatg ttggccagtg tggtctcaaa ctcctgacct catgatttgc ctgcctcggc
1741 ctcccaaagc actgggatta caggcgtgag ccaccacatc cagccagtga tccttaaaag
1801 attaagagat gactggacta ggtctacctt gatcttgaag attcccttgg aatgttgaga
1861 tttaggctta tttgagcact acctgcccaa ctgtcagtgc cagtgcatag cccttctttt
1921 gtctccctta tgaagactgc cctgcagggc tgagatgtgg caggagctcc cagggaaaaa
1981 ggaagtgcat ttgattggtg tgtattggcc aagttttgct tgttgtgtgc ttgaaagaaa
2041 atatctctga ccaacttctg tattcgtgga ccaaactgaa gctatatttt tcacagaaga
2101 agaagcagtg acggggacac aaattctgtt gcctggtgga aagaaggcaa aggccttcag
2161 caatctatat taccagcgct ggatcctttg acagagagtg gtccctaaac ttaaatttca
2221 agacggtata ggcttgatct gtcttgctta ttgttgcccc ctgcgcctag cacaattctg
2281 acacacaatt ggaacttact aaaaattttt ttttactgtt aaaaaaaaaa aaaaaaaaaa
2341 aaaaaaaaaa aaaaaaaa
//