LOCUS BC063283 5130 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens ADAM metallopeptidase with thrombospondin type 1
motif, 18, mRNA (cDNA clone MGC:71557 IMAGE:30343625), complete
cds.
ACCESSION BC063283
VERSION BC063283.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5130)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5130)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: g Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40806186.
FEATURES Location/Qualifiers
source 1..5130
/db_xref="H-InvDB:HIT000260804"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71557 IMAGE:30343625"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..5130
/gene="ADAMTS18"
/db_xref="GeneID:170692"
/db_xref="HGNC:HGNC:17110"
/db_xref="MIM:607512"
CDS 420..4085
/gene="ADAMTS18"
/codon_start=1
/product="ADAM metallopeptidase with thrombospondin type 1
motif, 18"
/protein_id="AAH63283.1"
/db_xref="GeneID:170692"
/db_xref="HGNC:HGNC:17110"
/db_xref="MIM:607512"
/translation="MECALLLACAFPAAGSGPPRGLAGLGRVAKALQLCCLCCASVAA
ALASDSSSGASGLNDDYVFVTPVEVDSAGSYISHDILHNGRKKRSAQNARSSLHYRFS
AFGQELHLELKPSAILSSHFIVQVLGKDGASETQKPEVQQCFYQGFIRNDSSSSVAVS
TCAGLSGLIRTRKNEFLISPLPQLLAQEHNHSSPAGHHPHVLYKRTAEEKIQRYRGYP
GSGRNYPGYSPSHIPHASQSRETEYHHRRLQKQHFCGRRKKYAPKPPTEDTYLRFDEY
GSSGRPRRSAGKSQKGLNVETLVVADKKMVEKHGKGNVTTYILTVMNMVSGLFKDGTI
GSDINVVVVSLILLEQEPGGLLINHHADQSLNSFCQWQSALIGKNGKRHDHAILLTGF
DICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHDGEG
NPCRKAEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQAGQYKYPD
KLPGQIYDADTQCKWQFGAKAKLCSLGFVKDICKSLWCHRVGHRCETKFMPAAEGTVC
GLSMWCRQGQCVKFGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCNNPKPQYG
GIFCPGSSRIYQLCNINPCNENSLDFRAQQCAEYNSKPFRGWFYQWKPYTKVEEEDRC
KLYCKAENFEFFFAMSGKVKDGTPCSPNKNDVCIDGVCELVGCDHELGSKAVSDACGV
CKGDNSTCKFYKGLYLNQHKANEYYPVVIIPAGARSIEIQELQVSSSYLAVRSLSQKY
YLTGGWSIDWPGEFPFAGTTFEYQRSFNRPERLYAPGPTNETLVFEILMQGKNPGIAW
KYALPKVMNGTPPATKRPAYTWSIVQSECSVSCGGGYINVKAICLRDQNTQVNSSFCS
AKTKPVTEPKICNAFSCPAYWMPGEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLH
SLCPVSTPTQVQACNSHACPPQWSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQ
CTSLPRPELQEGCVLGRCPKNSRLQWVASSWSECSATCGLGVRKREMKCSEKGFQGKL
ITFPERRCRNIKKPNLDLEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTCGGGVQTR
SVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPEKREDPSCVDFFNWCHLVPQHGVC
NHKFYGKQCCKSCTRKI"
BASE COUNT 1343 a 1280 c 1339 g 1168 t
ORIGIN
1 aatcaccgcg cggtggagag gcgggcgctc ggctccggcg cgctggggga gccagctggc
61 gctgtcttcc ccatcgcctc agacgctcac accgacacag acagacgcac agacgggcgg
121 gcagacaccg acagtctccc aaccgtttgc gctccagtcc cggcccaggg agccccccgt
181 accctctggg gtgccgcaaa ctgcagctcg gcaggcccgc gccgggagaa gggagggcgc
241 gcaggcggcc ggaggagggg aggtcccagc gcgcccccgc tgcgatgtga acggcggcgg
301 ctctcacctg gagccgcacc tggggcgccg agctccgggg ccgcggaaag aatgcgcgcc
361 gcccgtgcgc tccgcctgcc gcgtctggcc acccgcagcc gccgcgtccg cacctgacca
421 tggagtgcgc cctcctgctc gcgtgtgcct tcccggctgc gggttcgggc ccgccgaggg
481 gcctggcggg actggggcgc gtggccaagg cgctccagct gtgctgcctc tgctgtgcgt
541 cggtcgccgc ggccttagcc agtgacagca gcagcggcgc cagcggatta aatgatgatt
601 acgtctttgt cacgccagta gaagtagact cagccgggtc atatatttca cacgacattt
661 tgcacaacgg caggaaaaag cgatcggcgc agaatgccag aagctccctg cactaccgat
721 tttcagcatt tggacaggaa ctgcacttag aacttaagcc ctcggcgatt ttgagcagtc
781 actttattgt ccaggtactt ggaaaagatg gtgcttcaga gactcagaaa cccgaggtgc
841 agcaatgctt ctatcaggga tttatcagaa atgacagctc ctcctctgtc gctgtgtcta
901 cgtgtgctgg cttgtcaggt ttaataagga cacgaaaaaa tgaattcctc atctcgccat
961 tacctcagct tctggcccag gaacacaacc acagctcccc tgcgggtcac catcctcacg
1021 tactgtacaa aaggacagca gaggagaaga tccagcggta ccgtggctac cccggctctg
1081 gccggaatta tcctggttac tccccaagtc acattcccca tgcatctcag agtcgagaga
1141 cagagtatca ccatcgaagg ttgcaaaagc agcatttttg tggacgacgc aagaaatatg
1201 ctcccaagcc tcccacagag gacacctatc taaggtttga tgaatatggg agctctgggc
1261 gacccagaag atcagctgga aaatcacaaa agggcctcaa tgtggaaacc ctcgtggtgg
1321 cagacaagaa aatggtggaa aagcatggca agggaaatgt caccacatac attctcacag
1381 taatgaacat ggtttctggc ctatttaaag atgggactat tggaagtgac ataaacgtgg
1441 ttgtggtgag cctaattctt ctggaacaag aacctggagg attattgatc aaccatcatg
1501 cagaccagtc tctgaatagt ttttgtcaat ggcagtctgc cctcattgga aagaatggca
1561 agagacatga tcatgccatc ttactaacag gatttgatat ttgttcttgg aagaatgaac
1621 catgtgacac tctagggttt gcccccatca gtggaatgtg ctctaagtac cgaagttgta
1681 ccatcaatga ggacacagga cttggccttg ccttcaccat cgctcatgag tcagggcaca
1741 actttggtat gattcacgac ggagaaggga atccctgcag aaaggctgaa ggcaatatca
1801 tgtctcccac actgaccgga aacaatggag tgttttcatg gtcttcctgc agccgccagt
1861 atctcaagaa attcctcagc acacctcagg cggggtgtct agtggatgag cccaagcaag
1921 caggacagta taaatatccg gacaaactac caggacagat ttatgatgct gacacacagt
1981 gtaaatggca atttggagca aaagccaagt tatgcagcct tggttttgtg aaggatattt
2041 gcaaatcact ttggtgccac cgagtaggcc acaggtgtga gaccaagttt atgcccgcag
2101 cagaagggac cgtttgtggc ttgagtatgt ggtgtcggca aggccagtgc gtaaagtttg
2161 gggagctcgg gccccggccc atccacggcc agtggtccgc ctggtcgaag tggtcagaat
2221 gttcccggac atgtggtgga ggagtcaagt tccaggagag acactgcaat aaccccaagc
2281 ctcagtatgg tggcatattc tgtccaggtt ctagccgtat ttatcagctg tgcaatatta
2341 acccttgcaa tgaaaatagc ttggattttc gggctcaaca gtgtgcagaa tataacagca
2401 aacctttccg tggatggttc taccagtgga aaccctatac aaaagtggaa gaggaagatc
2461 gatgcaaact gtactgcaag gctgagaact ttgaattttt ttttgcaatg tccggcaaag
2521 tgaaagatgg aactccctgc tccccaaaca aaaatgatgt ttgtattgac ggggtttgtg
2581 aactagtggg atgtgatcat gaactaggct ctaaagcagt ttcagatgct tgtggcgttt
2641 gcaaaggtga taattcaact tgcaagtttt ataaaggcct gtacctcaac cagcataaag
2701 caaatgaata ttatccggtg gtcatcattc cagctggcgc ccgaagcatc gaaatccagg
2761 agctgcaggt ttcctccagt tacctcgcag ttcgaagcct cagtcaaaag tattacctca
2821 ccgggggctg gagcatcgac tggcctgggg agttcccctt cgctgggacc acgtttgaat
2881 accagcgctc tttcaaccgc ccggaacgtc tgtacgcgcc agggcccaca aatgagacgc
2941 tggtctttga aattctgatg caaggcaaaa atccagggat agcttggaag tatgcacttc
3001 ccaaggtcat gaatggaact ccaccagcca caaaaagacc tgcctatacc tggagtatcg
3061 tgcagtcaga gtgctccgtc tcctgtggtg gaggttacat aaatgtaaag gccatttgct
3121 tgcgagatca aaatactcaa gtcaattcct cattctgcag tgcaaaaacc aagccagtaa
3181 ctgagcccaa aatctgcaac gctttctcct gcccggctta ctggatgcca ggtgaatgga
3241 gtacatgcag caaggcctgt gctggaggcc agcagagccg aaagatccag tgtgtgcaaa
3301 agaagccctt ccaaaaggag gaagcagtgt tgcattctct ctgtccagtg agcacaccca
3361 ctcaggtcca agcctgcaac agccatgcct gccctccaca atggagcctt ggaccctggt
3421 ctcagtgttc caagacctgt ggacgagggg tgaggaagcg tgaactcctc tgcaagggct
3481 ctgccgcaga aaccctcccc gagagccagt gtaccagtct ccccagacct gagctgcagg
3541 agggctgtgt gcttggacga tgccccaaga acagccggct acagtgggtc gcttcttcgt
3601 ggagcgagtg ttctgcaacc tgtggtttgg gtgtgaggaa gagggagatg aagtgcagcg
3661 agaagggctt ccagggaaag ctgataactt tcccagagcg aagatgccgt aatattaaga
3721 aaccaaatct ggacttggaa gagacctgca accgacgggc ttgcccagcc catccagtgt
3781 acaacatggt agctggatgg tattcattgc cgtggcagca gtgcacagtc acctgtgggg
3841 gaggggtcca gacccggtca gtccactgtg ttcagcaagg ccggccttcc tcaagttgtc
3901 tgctccatca gaaacctccg gtgctacgag cctgtaatac aaacttctgt ccagctcctg
3961 aaaagagaga ggatccatcc tgcgtagatt tcttcaactg gtgtcaccta gttcctcagc
4021 atggtgtctg caaccacaag ttttacggaa aacaatgctg caagtcatgc acaaggaaga
4081 tctgatcttg gtgtcctccc cagcacctta gggccagggg cttacctttc aacctctaga
4141 gagaccagct gcctttgaga ccaggagctg agcaccgaga accatctgtg agctgccgct
4201 gtgatgaagg agcctgctct gaggaacaga caggttgcca gtaggcttct agctcaattc
4261 cctgaagcac gtggtactct gaagcacttg aaaatgggaa gcgatgacaa atctgacttt
4321 aaaaaaaatc tttgatttgc actgttatat gcaagaagtg gtgaatcaca ctgagatacg
4381 tcgatttggg gagagacccc cttttgaact tcaaagggtt caagggcaaa gacatctgtt
4441 ttaaaaaggt cctttatgac ttcaggtcaa agactgagac tcagaacttt caaatctgga
4501 tggaatacct tgcctaactg ttgcgtggag ttcacagttc gactaaccct gtgaacaccc
4561 aagccaggag ttctatgaga agccaaatgg tgctcgcaat tgtgcttgct gctggactgg
4621 caagcttcat gttatgttta tttggtgtgc gtgtgtcttt attattttgt gtaaactata
4681 ttctgcttat agagagtctc tgagactaaa attgacaact tgaaaagtat tccaaggaat
4741 attatgaaaa tagggcaaca tggactgttt aagatctcca tgtaattgaa attcatgcaa
4801 ggaaacaact catagaaaag ataaatatgg atgcccttca catgttatca acctcgtaac
4861 ttttggtgct tgctgaatca gtccatgaaa atctacagcc cgctctttgg gaatgctaca
4921 tacccatttc tggtatttaa aaaatatcta ggaggagcta aatgacaaaa cacagcagtg
4981 ttttgaggga gaaaggacca tcatttataa tgctctgtac atactaccag agctgcttgg
5041 aaaattaaag gccacttgtg gctttttcct accaactgat acgtttaaat ttgccctagg
5101 attgagctaa caacaaaaaa aaaaaaaaaa
//