LOCUS BC062583 2595 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens myeloid/lymphoid or mixed-lineage leukemia 5
(trithorax homolog, Drosophila), mRNA (cDNA clone IMAGE:5203790),
complete cds.
ACCESSION BC062583
VERSION BC062583.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2595)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2595)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 135 Row: g Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23503326
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..2595
/db_xref="H-InvDB:HIT000260495"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5203790"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2595
/gene="MLL5"
/gene_synonym="FLJ10078"
/gene_synonym="FLJ14026"
/gene_synonym="HDCMC04P"
/db_xref="GeneID:55904"
/db_xref="MIM:608444"
CDS 507..2336
/gene="MLL5"
/gene_synonym="FLJ10078"
/gene_synonym="FLJ14026"
/gene_synonym="HDCMC04P"
/codon_start=1
/product="MLL5 protein"
/protein_id="AAH62583.1"
/db_xref="GeneID:55904"
/db_xref="MIM:608444"
/translation="MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQ
LYTSSSHHSHSYIGLPYADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSS
ATTISTSEDGSYGTDVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLC
ERCQPRNLDKERAVLLQRRKRENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTAS
RVSKVNDKRRKKSGEKEQHISKCKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETK
IKAWMDRYEEANNNQYSEGVQREAQRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVES
HIQKNKKILKSAKDLPPDALIIEYRGKFMLREQFEANGYFFKRPYPFVLFYSKFHGLE
MCVDARTFGNEARFIRRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFDFDY
GNCKYKVDCACLKENPECPVLKRSSESMENINSGYETRRKKGKKDKDISKEKDTQNQN
ITLDCEGTTNKMKSPETKQRKLSPLRLSVSNNQEPDFIDDIEEKTPISNEVEMESEEQ
IAERKRKMVSWEASSLGLVTAALHMVIVAAFTWAFTLFFEVSE"
BASE COUNT 852 a 458 c 601 g 684 t
ORIGIN
1 gtgacactga gcgggcgcag ggggccgagt cggagaccgt gccggagttc gggagcggca
61 acagagtggg catagacact ccgagcagcc tcgccgtcgt ctctgcgttc ctgttgactg
121 cctggctgcc ccctccccta ctcctcggtt cctggtgaag aggctgcgcg ctgctgtttg
181 gggagggggt gtgtggagcc gggtcctgtg tccgcagtgg ctgctgtcgg ggggtcgcct
241 gttcgcggag gtgcggagag actccttggg ggtcgagcac ataacggggt tcgggtgtct
301 cgtgtgtgaa catcacaggt ctattctgga taagcaggtt ttgtgaagac atttattctt
361 tcttggacct cagatttacc agacatctca tgggtttgtg gatgcactta gatgtttgca
421 atgagcactg tggctggcat gccccagtgt tttggatacc aatgcatagg actccatagt
481 aatcgaattt accagaggcg aacgtcatga gcatagtgat cccattgggg gttgatacag
541 cagagacgtc atacttggaa atggctgcag gttcagaacc agaatccgta gaagctagcc
601 ctgtggtagt tgagaaatcc aacagttatc cccaccagtt atataccagc agctcacatc
661 attcacacag ttacattggt ttgccctatg cggaccataa ttatggtgct cgtcctcctc
721 cgacacctcc ggcttcccct cctccatcag tccttattag caaaaatgaa gtaggcatat
781 ttaccactcc taattttgat gaaacttcca gtgctactac aatcagcaca tctgaggatg
841 gaagttatgg tactgatgta accaggtgca tatgtggttt tacacatgat gatggataca
901 tgatctgttg tgacaaatgc agcgtttggc aacatattga ctgcatgggg attgataggc
961 agcatattcc tgatacatat ctatgtgaac gttgtcagcc taggaatttg gataaagaga
1021 gggcagtgct actacaacgc cggaaaaggg aaaatatgtc agatggtgat accagtgcaa
1081 ctgagagtgg tgatgaggtt cctgtggaat tatatactgc atttcagcat actccaacat
1141 caattacttt aactgcttca agagtttcca aagttaatga taaaagaagg aaaaaaagcg
1201 gggagaaaga acaacacatt tcaaaatgta aaaaggcatt tcgtgaagga tctaggaagt
1261 catcaagagt taagggttca gctccagaga ttgatccttc atctgatggt tcaaattttg
1321 gatgggagac aaagatcaaa gcatggatgg atcgatatga agaagcaaat aacaaccagt
1381 acagtgaggg tgttcagagg gaggcacaaa gaatagctct gagattaggc aatggaaatg
1441 acaaaaaaga gatgaataaa tccgatttga ataccaacaa tttgctcttc aaacctcctg
1501 tagagagcca tatacaaaag aataagaaaa ttcttaaatc tgcaaaagat ttgcctcctg
1561 atgcacttat cattgaatac agagggaagt ttatgctgag agaacagttt gaagcaaatg
1621 ggtatttctt taaaagacca tacccttttg tgttattcta ctctaaattt catgggctag
1681 aaatgtgtgt tgatgcaagg acttttggga atgaggctcg attcatcagg cggtcttgta
1741 cacccaatgc agaggtgagg catgaaattc aagatggaac catacatctt tatatttatt
1801 ctatacacag tattccaaag ggaactgaaa ttactattgc ctttgatttt gactatggaa
1861 attgtaagta caaggtggac tgtgcatgcc tcaaagaaaa cccagagtgc cctgttctaa
1921 aacgtagttc tgaatccatg gaaaatatca atagtggtta tgagaccaga cggaaaaaag
1981 gaaaaaaaga caaagatatt tcaaaagaaa aagatacaca aaatcagaat attactttgg
2041 attgtgaagg aacgaccaac aaaatgaaga gcccagaaac taaacaaaga aagctttctc
2101 cactgagact atcagtatca aataatcagg aaccagattt tattgatgat atagaagaaa
2161 aaactcctat tagtaatgaa gtagaaatgg aatcagagga gcagattgca gaaaggaaaa
2221 ggaagatggt aagttgggaa gccagtagtt tgggcttagt gacagctgct ctgcatatgg
2281 taattgttgc tgcctttaca tgggctttta cattattctt tgaagttagc gaatgatgtg
2341 ccattgagca tttttatttg gtttggtcat tgccatttaa ataaattcca ttaatcttgt
2401 atttttattg gttgttcatt agagatttaa gaatgtatga catttaagaa atatgaacat
2461 tttggaagta ataatatttt aataatgcca cactgaacta ttaataaatt ttaatgccac
2521 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2581 aaaaaaaaaa aaaaa
//