LOCUS BC060858 2746 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens suppressor of cytokine signaling 3, mRNA (cDNA clone
MGC:71791 IMAGE:30333577), complete cds.
ACCESSION BC060858
VERSION BC060858.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2746)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2746)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: b Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45439351.
FEATURES Location/Qualifiers
source 1..2746
/db_xref="H-InvDB:HIT000260160"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71791 IMAGE:30333577"
/tissue_type="Placenta, pre-eclamptic"
/clone_lib="NIH_MGC_148"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2746
/gene="SOCS3"
/gene_synonym="ATOD4"
/gene_synonym="CIS3"
/gene_synonym="Cish3"
/gene_synonym="MGC71791"
/gene_synonym="SOCS-3"
/gene_synonym="SSI-3"
/gene_synonym="SSI3"
/db_xref="GeneID:9021"
/db_xref="HGNC:HGNC:19391"
/db_xref="MIM:604176"
CDS 417..1094
/gene="SOCS3"
/gene_synonym="ATOD4"
/gene_synonym="CIS3"
/gene_synonym="Cish3"
/gene_synonym="MGC71791"
/gene_synonym="SOCS-3"
/gene_synonym="SSI-3"
/gene_synonym="SSI3"
/codon_start=1
/product="suppressor of cytokine signaling 3"
/protein_id="AAH60858.1"
/db_xref="GeneID:9021"
/db_xref="HGNC:HGNC:19391"
/db_xref="MIM:604176"
/translation="MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQES
GFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSF
SLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSP
PRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFL
DQYDAPL"
BASE COUNT 550 a 841 c 801 g 554 t
ORIGIN
1 ggctccgact tggactccct gctccgctgc tgccgcttcg gccccgcacg cagccagccg
61 cccgccgccc gcccggccca gctcccgccg cggccccttg ccgcggtccc tctcctggtc
121 ccctcccggt tggtccgggg gtgcgcaggg ggcagggcgg gcgcccaggg gaagctcgag
181 ggacgcgcgc gcgaaggctc ctttgtggac ttcacggccg ccaacatctg ggcgcagcgc
241 gggccaccgc tggccgtctc gccgccgcgt cgccttgggg acccgagggg gctcagcccc
301 aaggacggag acttcgattc gggaccagcc ccccgggatg cggtagcggc cgctgtgcgg
361 atgccgcgaa gcagctgcag ccgccgccgc gcagatccac gctggctccg tgcgccatgg
421 tcacccacag caagtttccc gccgccggga tgagccgccc cctggacacc agcctgcgcc
481 tcaagacctt cagctccaag agcgagtacc agctggtggt gaacgcagtg cgcaagctgc
541 aggagagcgg cttctactgg agcgcagtga ccggcggcga ggcgaacctg ctgctcagtg
601 ccgagcccgc cggcaccttt ctgatccgcg acagctcgga ccagcgccac ttcttcacgc
661 tcagcgtcaa gacccagtct gggaccaaga acctgcgcat ccagtgtgag gggggcagct
721 tctctctgca gagcgatccc cggagcacgc agcccgtgcc ccgcttcgac tgcgtgctca
781 agctggtgca ccactacatg ccgccccctg gagccccctc cttcccctcg ccacctactg
841 aaccctcctc cgaggtgccc gagcagccgt ctgcccagcc actccctggg agtcccccca
901 gaagagccta ttacatctac tccgggggcg agaagatccc cctggtgttg agccggcccc
961 tctcctccaa cgtggccact cttcagcatc tctgtcggaa gaccgtcaac ggccacctgg
1021 actcctatga gaaagtcacc cagctgccgg ggcccattcg ggagttcctg gaccagtacg
1081 atgccccgct ttaaggggta aagggcgcaa agggcatggg tcgggagagg ggacgcaggc
1141 ccctctcctc cgtggcacat ggcacaagca caagaagcca accaggagag agtcctgtag
1201 ctctgggggg aaagagggcg gacaggcccc tccctctgcc ctctccctgc agaatgtggc
1261 aggcggacct ggaatgtgtt ggagggaagg gggagtacca cctgagtctc cagcttctcc
1321 ggaggagcca gctgtcctgg tgggacgata gcaaccacaa gtggattctc cttcaattcc
1381 tcagcttccc ctctgcctcc aaacagggga cacttcggga atgctgaact aatgagaact
1441 gccagggaat cttcaaactt tccaacggaa cttgtttgct ctttgatttg gtttaaacct
1501 gagctggttg tggagcctgg gaaaggtgga agagagagag gtcctgaggg ccccagggct
1561 gcgggctggc gaaggaaatg gtcacacccc ccgcccaccc caggcgagga tcctggtgac
1621 atgctcctct ccctggctcc ggggagaagg gcttggggtg acctgaaggg aaccatcctg
1681 gtgccccaca tcctctcctc cgggacagtc accgaaaaca caggttccaa agtctacctg
1741 gtgcctgaga gcccagggcc cttcctccgt tttaaggggg aagcaacatt tggaggggac
1801 ggatgggctg gtcagctggt ctccttttcc tactcatact ataccttcct gtacctgggt
1861 ggatggagcg ggaggatgga ggagacggga catctttcac ctcaggctcc tggtagagaa
1921 gacaggggat tctactctgt gcctcctgac tatgtctggc taagagattc gccttaaatg
1981 ctccctgtcc catggagagg gacccagcat aggaaagcca catactcagc ctggatgggt
2041 ggagaggctg agggactcac tggagggcac caagccagcc cacagccagg gaagtgggga
2101 gggggggcgg aaacccatgc ctcccagctg agcactggga atgtcagccc agtaagtatt
2161 ggccagtcag gcgcctcgtg gtcagagcag agccaccagg tcccactgcc ccgagccctg
2221 cacagccctc cctcctgcct gggtggggga ggctggaggt cattggagag gctggactgc
2281 tgccaccccg ggtgctcccg ctctgccata gcactgatca gtgacaattt acaggaatgt
2341 agcagcgatg gaattacctg gaacagtttt ttgtttttgt ttttgttttt gtttttgtgg
2401 gggggggcaa ctaaacaaac acaaagtatt ctgtgtcagg tattgggctg gacagggcag
2461 ttgtgtgttg gggtggtttt tttctctatt tttttgtttg tttcttgttt tttaataatg
2521 tttacaatct gcctcaatca ctctgtcttt tataaagatt ccacctccag tcctctctcc
2581 tcccccctac tcaggccctt gaggctatta ggagatgctt gaagaactca acaaaatccc
2641 aatccaagtc aaactttgca catatttata tttatattca gaaaagaaac atttcagtaa
2701 tttataataa agagcactat tttttaatga aaaaaaaaaa aaaaaa
//