LOCUS BC060838 3720 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens aryl hydrocarbon receptor nuclear translocator, mRNA
(cDNA clone MGC:71732 IMAGE:5300334), complete cds.
ACCESSION BC060838
VERSION BC060838.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3720)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3720)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: p Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 30795239
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..3720
/db_xref="H-InvDB:HIT000260140"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71732 IMAGE:5300334"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3720
/gene="ARNT"
/gene_synonym="bHLHe2"
/gene_synonym="HIF-1beta"
/gene_synonym="HIF1B"
/gene_synonym="HIF1BETA"
/gene_synonym="TANGO"
/db_xref="GeneID:405"
/db_xref="HGNC:HGNC:700"
/db_xref="MIM:126110"
CDS 137..1387
/gene="ARNT"
/gene_synonym="bHLHe2"
/gene_synonym="HIF-1beta"
/gene_synonym="HIF1B"
/gene_synonym="HIF1BETA"
/gene_synonym="TANGO"
/codon_start=1
/product="ARNT protein"
/protein_id="AAH60838.1"
/db_xref="GeneID:405"
/db_xref="HGNC:HGNC:700"
/db_xref="MIM:126110"
/translation="MAATTANPEMTSDVPSLGPAIASGNSGPGIQGGGAIVQRAIKRR
PGLDFDDDGEGNSKFLRCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRR
NKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLT
DQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQQQSEWFGSTLYDQVHPDDV
DKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSSSVDP
VSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSK
FCLVAIGRLQVTSSPNCTDMSNVCQPTELISRHNIEGIFTFVDHRCVATVGYQPQELL
GKNIVEFCHPEDQQLLRDSFQQEL"
BASE COUNT 977 a 791 c 902 g 1050 t
ORIGIN
1 gggttccgcg gtagcggagg cggcggtcag gcgccgcttc tggggagtgg cctttctttt
61 cccctccctc ccggttcggt ggcggcggct cctcccactg ggggggggtg gcgcggcggc
121 ggtggcatct gcggccatgg cggcgactac tgccaacccc gaaatgacat cagatgtacc
181 atcactgggt ccagccattg cctctggaaa ctctggacct ggaattcaag gtggaggagc
241 cattgtccag agggctatta agcggcgacc agggctggat tttgatgatg atggagaagg
301 gaacagtaaa tttttgaggt gtgatgatga tcagatgtct aacgataagg agcggtttgc
361 caggtcggat gatgagcaga gctctgcgga taaagagaga cttgcaaggg aaaatcacag
421 tgaaattgaa cggcggcgac ggaacaagat gacagcctac atcacagaac tgtcagatat
481 ggtacccaca tgtagtgccc tggctcgaaa accagacaag ctaaccatct tacgcatggc
541 agtttctcac atgaagtcct tgcggggaac tggcaacaca tccactgatg gctcctataa
601 gccgtctttc ctcactgatc aggaactgaa acatttgatc ttggaggcag cagatggctt
661 tctgtttatt gtctcatgtg agacaggcag ggtggtgtat gtctctgact ccgtgactcc
721 tgttttgaac cagcaacagt ctgaatggtt tggcagcaca ctctatgatc aggtgcaccc
781 agatgatgtg gataaacttc gtgagcagct ttccacttca gaaaatgccc tgacagggcg
841 tatcctggat ctaaagactg gaacagtgaa aaaggaaggt cagcagtctt ccatgagaat
901 gtgtatgggc tcaaggagat cgtttatttg ccgaatgagg tgtggcagta gctctgtgga
961 cccagtttct gtgaataggc tgagctttgt gaggaacaga tgcaggaatg gacttggctc
1021 tgtaaaggat ggggaacctc acttcgtggt ggtccactgc acaggctaca tcaaggcctg
1081 gcccccagca ggtgtttccc tcccagatga tgacccagag gctggccagg gaagcaagtt
1141 ttgcctagtg gccattggca gattgcaggt aactagttct cccaactgta cagacatgag
1201 taatgtttgt caaccaacag agttaatctc ccgacacaac attgagggta tcttcacttt
1261 tgtggatcac cgctgtgtgg ctactgttgg ctaccagcca caggaactct taggaaagaa
1321 tattgtagaa ttctgtcatc ctgaagacca gcagcttcta agagacagct tccaacagga
1381 actctagcca agaaccacgg cctacactct ccaacacaat ccagaggcca caactaggtc
1441 ccacagctaa tttacccctg gagatgggct caggacagct gcctacccta gtctcaccaa
1501 tcgtggatct aactttgctc ctgagactgg acagactgca ggacaattcc agacacggac
1561 agcagagggt gtgggtgtct ggccacagtg gcagggccag cagcctcatc atcgttcaag
1621 ttctagtgag caacatgttc aacaaccgcc agcacagcaa cctggccagc ctgaggtctt
1681 ccaggagatg ctgtccatgc tgggagatca gagcaacagc tacaacaatg aagaattccc
1741 tgatctaact atgtttcccc ccttttcaga atagaactat tggggtgagg ataaggggtg
1801 ggggagaaaa aatcactgtt tgtttttaaa aagcaaatct ttctgtaaac agaataaaag
1861 ttcctctccc ttcccttccc tcacccctga catgtacccc ctttcccttc tggctgttcc
1921 cctgctctgt tgcctctcta aggtaacatt tatagaagaa atggaatgaa tctccaaggc
1981 ttttaggact gtctgaaaat ttgaggctgg gtgaagttat aacacctttc cttatgtctc
2041 ctgacctgaa attgtatagt gttgatttgt gctgagatca agaggcaggt tagaagaacc
2101 tgacatccac tgtttgcctt ggatagtatg gcttgttttt ggaaagaaat tctgaagaga
2161 gtggaggaga ggagagatgt cctcatattt gaggaccatg aaacattgta ggtatatatg
2221 gggctttagc aagtttgagc ataggctctt tttgctgcct gtgagcagtc cctctggaaa
2281 gaaacgtgtg agtaagtgag agagagtgtg tgtgtatgtg tgtgtgtgtg tgtgtgtgtg
2341 cgcacacatg cttctgtatt tcactctttc tccctattag ggagttatgc aaaatttgtc
2401 cccgatttta cctttgtctt tctgtgtact tttcaaagag tcctaaggag ttaaatcttc
2461 caggtatttt ccacttagta ttgcagccaa agaatattta aataaacgtc tttgctgcgc
2521 ttgcatccat gcccagccaa tatacaactg taaagcaaat atagaaagtc ggctgttgat
2581 acgattgtct gttatcgaac acattcagtg ataaagctgg gttactgctg cttttggtgc
2641 tctcacgtta tctggaagat ctgcaaacat tacctaaata ggctggcaag ataaacactt
2701 tctggaaccc gagacttggc cataaagata atgctgcatt tttctgtcag aatcacatat
2761 gatgtgtgtt ctgtagaggt tatttctgca tggaaactca acttcttgga ttagccgtcc
2821 cagtgaaaat cctcattgtt ggagtgtaaa ccaaatacga agccctcttg caaagtagcc
2881 tctttcatcc catactcaaa ataccaagtt tagcaagcaa ctgagattta agtctctctg
2941 gccctaagag gtttttcctc tttgctccct ccaatcttga gattgggttt tgctttagag
3001 tgcaagtatc ataattccgt atgatagatg gggcctggac acacatctca acagggtcac
3061 ttggtaatta acaatagcca tataaatgcg gatacaggtt actaccctca ccctttacct
3121 tcctcaggta acagtcgtag ataccagctt tttttttttt ttttttttta aattggcttt
3181 ggccagtagc taaagtgcaa gactgaatta atgagaagat atattaaatg tagtcatagg
3241 ggactgagga gcaagggtgg ccttgaagag gccaaaggaa tgtccatttg ctgagtttcc
3301 cttccttatg tctccagtct ggtgccaggt agtggagtaa aaaaggagac agtttatttt
3361 tttattctat gtgcacactt acagtataca tatatattta tatcacaatt tacgaaacca
3421 aaaagttgag tttccaatgg aacccttgtt ttttaataat cgacttttta aatgtgatca
3481 ggactataat attgtacagt tattataggg cttttgggga aggggaggat agcgagaaga
3541 tgctctgggg gttttgtttt tgcttttcct tcagggtttt atttttgact gttttgtttt
3601 cttgttggcc atttctgtat tgctggcatc tgtgctaagc tttacagtgg caaaaataat
3661 gacatgtagc aaagattttc aaacaaaata ttttttcctt ttgcaaaaaa aaaaaaaaaa
//