LOCUS BC060804 3369 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens ADAM metallopeptidase domain 12, mRNA (cDNA clone
MGC:71621 IMAGE:30348514), complete cds.
ACCESSION BC060804
VERSION BC060804.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3369)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3369)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: j Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13259517.
FEATURES Location/Qualifiers
source 1..3369
/db_xref="H-InvDB:HIT000260106"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71621 IMAGE:30348514"
/tissue_type="Placenta, pre-eclamptic"
/clone_lib="NIH_MGC_148"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3369
/gene="ADAM12"
/gene_synonym="MCMP"
/gene_synonym="MCMPMltna"
/gene_synonym="MLTN"
/gene_synonym="MLTNA"
/db_xref="GeneID:8038"
/db_xref="HGNC:HGNC:190"
/db_xref="MIM:602714"
CDS 353..2566
/gene="ADAM12"
/gene_synonym="MCMP"
/gene_synonym="MCMPMltna"
/gene_synonym="MLTN"
/gene_synonym="MLTNA"
/codon_start=1
/product="ADAM metallopeptidase domain 12"
/protein_id="AAH60804.1"
/db_xref="GeneID:8038"
/db_xref="HGNC:HGNC:190"
/db_xref="MIM:602714"
/translation="MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVS
ASVRSGDLWIPVKSFDSKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQD
GTDVSLARNYTGHCYYHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNR
YKLFPAKKLKSVRGSCGSHHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIV
ADNREFQRQGKDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDP
FTSLHEFLDWRKMKLLPRKSHDNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDH
SDNPLGAAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSC
SRKDLETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNA
TTCTLKPDAVCAHGLCCEDCQLKPAGTACRDSSNSCDLPEFCTGASPHCPANVYLHDG
HSCQDVDGYCYNGICQTHEQQCVTLWGPGAKPAPGICFERVNSAGDPYGNCGKVSKSS
FAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIETNIPLQQGGRILCRGTHVYLGDDMP
DPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQCHGRGVCNNRKNCHCEAHWAPP
FCDKFGFGGSTDSGPIRQAGKEARQEAAESNRERGQGQEPVGSQEHASTASLTLI"
BASE COUNT 862 a 868 c 957 g 682 t
ORIGIN
1 ggactgctgg ccgtggatcc atttcacagg cctgccttct ctcactaacg ctcttcctag
61 tccccgggcc aactcggaca gtttgctcat ttattgcaac ggtcaaggct ggcttgtgcc
121 agaacggcgc gcgcgcgcgc acgcacgcac acacacgggg ggaaactttt ttaaaaatga
181 aaggctagaa gagctcagcg gcggcgcggg cgctgcgcga gggctccgga gctgactcgc
241 cgaggcagga aatccctccg gtcgcgacgc ccggccccgg ctcggcgccc gcgtgggatg
301 gtgcagcgct cgccgccggg cccgagagct gctgcactga aggccggcga cgatggcagc
361 gcgcccgctg cccgtgtccc ccgcccgcgc cctcctgctc gccctggccg gtgctctgct
421 cgcgccctgc gaggcccgag gggtgagctt atggaaccaa ggaagagctg atgaagttgt
481 cagtgcctct gttcggagtg gggacctctg gatcccagtg aagagcttcg actccaagaa
541 tcatccagaa gtgctgaata ttcgactaca acgggaaagc aaagaactga tcataaatct
601 ggaaagaaat gaaggtctca ttgccagcag tttcacggaa acccactatc tgcaagacgg
661 tactgatgtc tccctcgctc gaaattacac gggtcactgt tactaccatg gacatgtacg
721 gggatattct gattcagcag tcagtctcag cacgtgttct ggtctcaggg gacttattgt
781 gtttgaaaat gaaagctatg tcttagaacc aatgaaaagt gcaaccaaca gatacaaact
841 cttcccagcg aagaagctga aaagcgtccg gggatcatgt ggatcacatc acaacacacc
901 aaacctcgct gcaaagaatg tgtttccacc accctctcag acatgggcaa gaaggcataa
961 aagagagacc ctcaaggcaa ctaagtatgt ggagctggtg atcgtggcag acaaccgaga
1021 gtttcagagg caaggaaaag atctggaaaa agttaagcag cgattaatag agattgctaa
1081 tcacgttgac aagttttaca gaccactgaa cattcggatc gtgttggtag gcgtggaagt
1141 gtggaatgac atggacaaat gctctgtaag tcaggaccca ttcaccagcc tccatgaatt
1201 tctggactgg aggaagatga agcttctacc tcgcaaatcc catgacaatg cgcagcttgt
1261 cagtggggtt tatttccaag ggaccaccat cggcatggcc ccaatcatga gcatgtgcac
1321 ggcagaccag tctgggggaa ttgtcatgga ccattcagac aatccccttg gtgcagccgt
1381 gaccctggca catgagctgg gccacaattt cgggatgaat catgacacac tggacagggg
1441 ctgtagctgt caaatggcgg ttgagaaagg aggctgcatc atgaacgctt ccaccgggta
1501 cccatttccc atggtgttca gcagttgcag caggaaggac ttggagacca gcctggagaa
1561 aggaatgggg gtgtgcctgt ttaacctgcc ggaagtcagg gagtctttcg ggggccagaa
1621 gtgtgggaac agatttgtgg aagaaggaga ggagtgtgac tgtggggagc cagaggaatg
1681 tatgaatcgc tgctgcaatg ccaccacctg taccctgaag ccggacgctg tgtgcgcaca
1741 tgggctgtgc tgtgaagact gccagctgaa gcctgcagga acagcgtgca gggactccag
1801 caactcctgt gacctcccag agttctgcac aggggccagc cctcactgcc cagccaacgt
1861 gtacctgcac gatgggcact catgtcagga tgtggacggc tactgctaca atggcatctg
1921 ccagactcac gagcagcagt gtgtcacgct ctggggacca ggtgctaaac ctgcccctgg
1981 gatctgcttt gagagagtca attctgcagg tgatccttat ggcaactgtg gcaaagtctc
2041 gaagagttcc tttgccaaat gcgagatgag agatgctaaa tgtggaaaaa tccagtgtca
2101 aggaggtgcc agccggccag tcattggtac caatgccgtt tccatagaaa caaacatccc
2161 cctgcagcaa ggaggccgga ttctgtgccg ggggacccac gtgtacttgg gcgatgacat
2221 gccggaccca gggcttgtgc ttgcaggcac aaagtgtgca gatggaaaaa tctgcctgaa
2281 tcgtcaatgt caaaatatta gtgtctttgg ggttcacgag tgtgcaatgc agtgccacgg
2341 cagaggggtg tgcaacaaca ggaagaactg ccactgcgag gcccactggg cacctccctt
2401 ctgtgacaag tttggctttg gaggaagcac agacagcggc cccatccggc aagcagggaa
2461 agaagcaagg caggaagctg cagagtccaa cagggagcgc ggccagggcc aggagcccgt
2521 gggatcgcag gagcatgcgt ctactgcctc actgacactc atctgagccc tcccatgaca
2581 tggagaccgt gaccagtgct gctgcagagg aggtcacgcg tccccaaggc ctcctgtgac
2641 tggcagcatt gactctgtgg ctttgccatc gtttccatga caacagacac aacacagttc
2701 tcggggctca ggaggggaag tctagcctac caggcacgtc tgcagaaaca gtgcaaggaa
2761 gggcagcgac ttcctggttg agcttctgct aaaacatgga catgcttcag tgctgctcct
2821 gagagagtag caggttacca ctctggcagg ccccagccct gcagcaagga ggaagaggac
2881 tcaaaagtct ggcctttcac tgagcctcca cagcagtggg ggagaagcaa gggttgggcc
2941 cagtgtcccc tttccccagt gacacctcag ccttggcagc cctgatgact ggtctctggc
3001 tgcaacttaa tgctctgata tggcttttag catttattat atgaaaatag cagggtttta
3061 gtttttaatt tatcagagac cctgccaccc attccatctc catccaagca aactgaatgg
3121 caatgaaaca aactggagaa gaaggtagga gaaagggcgg tgaactctgg ctctttgctg
3181 tggacatgcg tgaccagcag tactcaggtt tgagggtttg cagaaagcca gggaacccac
3241 agagtcacca acccttcatt taacaagtaa gaatgttaaa aagtgaaaac aatgtaagag
3301 cctaactcca tcccccgtgg ccattactgc ataaaataga gtgcatttga aataaaaaaa
3361 aaaaaaaaa
//