LOCUS BC060767 7102 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens ArfGAP with coiled-coil, ankyrin repeat and PH domains
2, mRNA (cDNA clone MGC:71512 IMAGE:30343546), complete cds.
ACCESSION BC060767
VERSION BC060767.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7102)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 7102)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: f Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40254841.
FEATURES Location/Qualifiers
source 1..7102
/db_xref="H-InvDB:HIT000260069"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71512 IMAGE:30343546"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..7102
/gene="ACAP2"
/gene_synonym="CNT-B2"
/db_xref="GeneID:23527"
/db_xref="HGNC:HGNC:16469"
/db_xref="MIM:607766"
CDS 177..2513
/gene="ACAP2"
/gene_synonym="CNT-B2"
/codon_start=1
/product="ArfGAP with coiled-coil, ankyrin repeat and PH
domains 2"
/protein_id="AAH60767.1"
/db_xref="GeneID:23527"
/db_xref="HGNC:HGNC:16469"
/db_xref="MIM:607766"
/translation="MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIA
MIDTGKAFCVANKQFMNGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQ
RSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILT
ATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMK
DLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKR
ASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVS
PTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESK
EKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSK
VRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYV
ERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSEIQ
QSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAE
ALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHAT
VLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEG
LYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF"
BASE COUNT 2208 a 1242 c 1393 g 2259 t
ORIGIN
1 ggcctgacta gtcgtcgccg tcttcgcggc tgctatgacc agcgggcgag gcgcccttcg
61 cagctccgcg caacgctagt cgcggccgtg cgcccgccgt agccgtctgc gtcccagcgc
121 ggccgctccc gcggccccct cggctttgcc agcgccgcct gcgaggcgga ggcaggatga
181 agatgactgt ggatttcgag gagtgtctga aggactcgcc ccgcttcagg gcagctttgg
241 aagaagtaga aggtgatgtg gcagaattgg aactaaaact tgataagctt gtgaaacttt
301 gtattgcaat gattgatact ggaaaagcct tttgtgttgc aaataaacag ttcatgaatg
361 ggattcgaga cctggctcag tattctagta atgatgctgt cgttgagaca agtttgacca
421 agttttctga cagtcttcaa gaaatgataa attttcacac aatcctgttt gaccaaactc
481 agagatcaat taaggcacag cttcagaact ttgttaaaga agatcttaga aaattcaaag
541 atgccaagaa gcaattcgaa aaagtcagtg aagaaaaaga aaatgcgtta gtaaaaaatg
601 cccaagtaca aagaaacaaa caacatgaag ttgaagaagc caccaacatt ctgacagcaa
661 caagaaaatg tttccgacac atagccctcg attatgtgct tcagattaat gttcttcaat
721 caaaaaggag atcagaaatc ctaaaatcaa tgttgtcatt tatgtatgcc catttggcct
781 tctttcatca aggatatgat ctgtttagtg aacttggacc ctacatgaag gatcttggtg
841 cacagttgga tcgactggtt gtggatgcag caaaggagaa aagagaaatg gagcaaaaac
901 attccaccat tcaacaaaag gatttctcca gtgatgattc taagttagaa tataacgtag
961 atgctgcaaa tggcatagtt atggaaggat atctgttcaa acgagccagc aatgccttca
1021 aaacttggaa caggcgctgg ttttcaatac agaataatca gttggtttac cagaaaaaat
1081 ttaaggataa tccgactgtg gtagttgaag acctcaggct ttgcacagtg aaacattgtg
1141 aagacataga gcgacgattc tgctttgagg tggtctcgcc aacaaaaagt tgcatgctcc
1201 aggcagattc cgaaaagctg cgccaggcat ggattaaggc tgttcagacc agtattgcta
1261 ctgcttatag agagaagggt gatgaatcag agaagctgga taagaaatca tctccatcca
1321 caggaagcct agattctgga aatgagtcca aagagaaatt attgaaagga gaaagtgcgc
1381 ttcagcgggt ccagtgtatc cctggcaatg ccagctgttg tgactgtggc ctggcagatc
1441 cacggtgggc cagcatcaac ctgggcatca ccttgtgtat cgagtgctcc ggaattcacc
1501 ggagccttgg ggttcatttt tcaaaagtac gatctttaac tttagacacc tgggagccag
1561 aacttttaaa gcttatgtgt gagttgggga atgatgttat aaatcgagtt tatgaagcta
1621 atgtggaaaa aatgggaata aagaaacccc aaccaggaca aagacaggag aaggaggcat
1681 atatcagagc aaaatatgtg gagaggaaat ttgtggataa atattctata tcattatcac
1741 ctcctgagca gcaaaaaaag tttgtctcta aaagttctga agaaaagagg ctgagcattt
1801 ctaaatttgg gccaggggac caagtcagag catctgccca aagttcagtc agaagtaatg
1861 acagtgaaat tcagcagagc tctgatgatg gaagagaatc tttaccctcc acggtgtcag
1921 ccaatagttt atatgagcct gaaggagaaa ggcaagattc ttctatgttt cttgactcga
1981 aacatcttaa tccaggactt cagctttata gggcgtcata tgaaaaaaac cttcctaaaa
2041 tggctgaggc tttggctcat ggtgcagacg tgaactgggc caattcagag gaaaacaaag
2101 cgacgccact tattcaggct gtattagggg gctctttggt gacgtgtgag ttcctcctac
2161 agaatggtgc taatgtcaac caaagagatg tccaagggcg gggaccattg caccatgcca
2221 ccgtcttagg gcacacaggg caggtatgtt tattcctaaa acgaggtgcc aatcaacatg
2281 ccactgatga agaagggaaa gaccctttga gcatagctgt ggaagcagcc aatgctgata
2341 tagtcacctt gttacgttta gcaagaatga atgaagagat gcgggaatca gaaggacttt
2401 atggacagcc aggtgatgaa acttatcagg acatatttcg tgatttttcc caaatggcat
2461 ccaataatcc agagaaacta aatcgtttcc agcaagattc acagaaattc tgaatttttt
2521 taaaaatggg aaaatatgaa atctggtgac cccctaatgt atacagctaa aaattcacaa
2581 tttttttact gctttaattc tacttaattt tggtagatat tgaatggctt ggaaaagagg
2641 tacccattca tatatttata aattaaaaca tagttatcta gtagtaggag aggaacctag
2701 tttaggacct cttttattaa aaaagcctat ttaaagggct atttctgtag acagaagttc
2761 agtctagatt taggccatct ctaggttaca agatgatagg aggttagaca aaagtgattc
2821 ttttgccaat gggtggtggc attgattttt ttcctccatg catcttgccc aggatcactc
2881 agtcaagcat gtcttcatca agtggaagcc aactgtcctg cctgcctcaa gaatatgtgt
2941 tttctttagc ttccctgagg atttttggtg gttcagaaat aggtgtgtgt gttgatgtgt
3001 ttttggtaac ctagctttca tacacataat atatgattta ttagaactag agaatgtgtt
3061 ttccccgttt gttcataaat gcggtcggtt atacttctta ggtgacaggt tattgtccag
3121 tactttaatg tatgtatgta taatggctgt acaggtagac cataattcag tcctttagat
3181 ttattttatg cagcaaaaag aagctctttt tttttttaat cacaaaaaaa aaccccagtt
3241 caaaatgtgt agttcttcat tgttgggttg attccccaaa accttgacag atgtatcgat
3301 ggaataaaag tatgttttaa aggttacttg aatgtcacaa aattatgcct tcatcaaaac
3361 tttaaaggaa aaatcaattt ataaaatcat gtaggccatt tttatatttg aaatttgtcc
3421 ttttaaagat agttttgctg ttgctcctag tgaaagaaaa atctctgtac aaaggagaaa
3481 aagaacccca cttattctta gttaatacta aaatatagca ataaattgct gtttattttt
3541 tctacatcta ttttgtgtac ttgtacacag tgtacattct tttaaattat atcgtgtata
3601 tagctttagt attcggttac atgattcaca gacccctgaa ttccaatatt atggataaac
3661 attaccattt atatgctaca aattagtctg attccatctt tgaaaatgtc ttaaagtata
3721 aaataattaa tttgcttttt tttttttttt tttcccgaga tggcgtcttg ctgtgtcacc
3781 caggctggag tgcagtggca cgatctcagc tcactgcagc ctcctcctct tgggttcaag
3841 caattctcct gcctcagcct cccgagtagc tgggactaca ggcacccgcc accattccga
3901 gctaatttct atatttttag taaagacggg tttcaccatt ttggccaggt tggtctcaaa
3961 ctcctgacct caggtgatca gcctgcttta gcctcccaga gtgctgggat tacaggcgtg
4021 agccaccgca cccagcctaa tttgcctttt gattccttcc cattgttgtc aaaaattaag
4081 tctattcttc ttttagaaat tatatgtaaa tgatattatt gatactcttt ctaaataaga
4141 ggttttaaaa tatataaaaa ctttatgatc caattataga taaattttct aacatttccc
4201 agtcactagg gttttataag ttgattaaac atcaaatcag aatctagcca agcaggaatt
4261 atattgaaat aagttcacat tacagaaaag gttccataat ttggccaaac tgcatgcatg
4321 taatgcttat ttagtaatgg tcactgtatg ttagataagg ataaaaatat atttgtgaat
4381 tacttctgag gaaatgctaa cttccacagc attgtattta attataacaa taacaggaac
4441 attaaatctt tatctttgct gtttcacctc aaagtcatag atcatctggc tttttaggca
4501 ccttcactaa aggcaaaaat ctgatttgta gtttttatta gcatgtacct tgaaattatt
4561 tgaccaagaa gctcaaagaa aagaagtacg ttaaagaaaa agaaaaaacc tcacttttcc
4621 tttatagtgt cccttcctgt tttaattcct aaagatcctg acttttatct gaggaagtct
4681 aggtagtttt ccttttggat ctggccattg gtgcgtgttt cattcagatc acctctggaa
4741 tctctgtggt tgtgaaggca attccttatg agactcttgc ctcctgtggc ttacgtgatg
4801 aattgttaat atggcagtaa ttaattagta tctacttaaa tttagtggtc agaaatgtat
4861 ttgaagtgcc ttaaagatga tcatggttca gaatatcttc agagaaagca aaatctttaa
4921 tattgcaggg agcctagcaa tacaaataca catttctgtg gcttgatttc ttgaatatgc
4981 tgagacccaa tttggactac atttggcaga aatcatggag taaacagcaa ggctttaaat
5041 taaattaata gttacaaggt aggttggctc ttaggtgaat ttagccatgt caactaatag
5101 cttttatatg gtatgtaaca aatctgaatt atgttatgct gtgaattatt cagtgcatta
5161 taagaaatct tagttaatca tgcttttggg cttcattagt caatgtgatt ggccttttat
5221 tttctttcca taacttatct gctattatta gtttcttatt ccttattatt aatctgttag
5281 ctcattatca ttagcttact aacttgaaag ttagattaat atcaaaataa gaatagcagc
5341 actatgaaga gttaataaaa tgcaatttca tgttagagct agaataaaag taattgagca
5401 gtcatttgca aatgcttcat tataacattt atgtgcttaa gatttctaag gttttaaaaa
5461 gttaccttta atacaatcct tagaaactca gaaatttcct gatattcatt agattatggt
5521 gtttgcctaa tttataccgg ttttcactgt atattttaat gaactttgat tggttacttt
5581 tccagacata cagatttaat ttggaatatg aactttggtt cttcatgagt gcattttgaa
5641 aaagaaaaaa agtacacatt cagaatctgg ccaatttaag tttgtatttt aaaaatattt
5701 tatgcatgtt aagtatggtc gcagtaaatg aaattgtgtt taagactaaa tttactaccg
5761 ttttgaacag acattcccag atcattctta tattgtcaga taacacttgt gtataatatc
5821 actttggacc atggacatga gctggaaaaa tgatgtattt ttgtagattg tatgtccaga
5881 atgactttag aaccgcatga tacggtggaa ggagcactgg actagtcgtc actacccttt
5941 ttggattcag ggctcctcac aattaaaatg agtgtaatga aacaaggtga aaatatagaa
6001 gcatcccttt gtatactgtt ttgctactta cagtgtactt ggcattgctt tatctcactg
6061 gattctcatg gtaggatttc tgagatctta atctaagctc caaagttgtc tacttttttg
6121 atcctagggt gctccttttg ttttacagag cagggtcact tgatttgcta gctggtggca
6181 gaattggcac cattacccag gtctgactga ccaccagtca gaggcacttt atttgtatca
6241 tgaaatgatt tgaaatcatt gtaaagcagc gaagtctgat aatgaatgcc agctttcctt
6301 gtgctttgat aacaaagact ccaaatattc tggagaacct ggataaaagt ttgaagggct
6361 agattgggat ttgaagacaa aattgtagga aatcttacat ttttgcaata acaaacatta
6421 atgaaagcaa aacattataa aagtaatttt aattcaccac atacttatca atttcttgat
6481 gcttccaaat gacatctaca gatatggttt tgtggacatc tttttctgtt tacataaatt
6541 tatccactta aaatgtgata atgtggagac aaagcaagat ttgattacat aaacttttct
6601 ctgcattggt cttttcacta tcttatttgc taacttttct tatttttctt caacctcccc
6661 accctccatt ttttggatat taaacaggga aagcttgcta cattataaag attgttggca
6721 ccatttattt tacacaaagg ctaaaggtta acttttggaa atgatgagct acttttatat
6781 atgtgtttac tcatgctttg tgatatttct ggatcattcc agtcataaag acttattaca
6841 tgtactattt cttgctacct gtgaaaaggt atattttaaa gaatgtataa ccaacagtcc
6901 atttactttt tattagtatg tagaggattt gtatctaatt catgaatgta gttttacagt
6961 agtttgtcat tgtaaatgga gcaaagtaca ttatcttcta aaatgtacat tatgtaagaa
7021 ttgtaaatat acttaagtaa tttgtatgcc aaaaaattac aataagtcaa taaagatctc
7081 acctctgaaa aaaaaaaaaa aa
//