LOCUS BC058013 1440 bp mRNA linear HUM 04-NOV-2003
DEFINITION Homo sapiens optic atrophy 1 (autosomal dominant), mRNA (cDNA clone
IMAGE:6108066), complete cds.
ACCESSION BC058013
VERSION BC058013.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1440)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1440)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-SEP-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 48 Row: h Column: 17
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1440
/db_xref="H-InvDB:HIT000259803"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6108066"
/tissue_type="Bone marrow, acute myelogenous leukemia"
/clone_lib="NIH_MGC_55"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1440
/gene="OPA1"
/gene_synonym="FLJ12460"
/gene_synonym="KIAA0567"
/gene_synonym="largeG"
/gene_synonym="NPG"
/gene_synonym="NTG"
/db_xref="GeneID:4976"
/db_xref="MIM:605290"
CDS 136..966
/gene="OPA1"
/gene_synonym="FLJ12460"
/gene_synonym="KIAA0567"
/gene_synonym="largeG"
/gene_synonym="NPG"
/gene_synonym="NTG"
/codon_start=1
/product="OPA1 protein"
/protein_id="AAH58013.1"
/db_xref="GeneID:4976"
/db_xref="MIM:605290"
/translation="MTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHN
ALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQC
VHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRH
FLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTE
VRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
"
BASE COUNT 501 a 229 c 307 g 403 t
ORIGIN
1 ggggcgcaga ccatgaattc aggaactttt aacaccacag tggatatcaa gcttaaacag
61 tggactgata aacaacttcc taataaagca gtagaggttg cttgggagac cctataagaa
121 gaattttccc gctttatgac agaaccgaaa gggaaagagc atgatgacat atttgataaa
181 cttaaagagg ctgttaagga agaaagtatt aaacgacaca agtggaatga ctttgcggag
241 gacagcttga gggttattca acacaatgct ttggaagacc gatccatatc tgataaacag
301 caatgggatg cagctattta ttttatggaa gaggctctgc aggctcgtct caaggatact
361 gaaaatgcaa ttgaaaacat ggtgggtcca gactggaaaa agaggtggtt atactggaag
421 aatcggaccc aagaacagtg tgttcacaat gaaaccaaga atgaattgga gaagatgttg
481 aaatgtaatg aggagcaccc agcttatctt gcaagtgatg aaataaccac agtccggaag
541 aaccttgaat cccgaggagt agaagtagat ccaagcttga ttaaggatac ttggcatcaa
601 gtttatagaa gacatttttt aaaaacagct ctaaaccatt gtaacctttg tcgaagaggt
661 ttttattact accaaaggca ttttgtagat tctgagttgg aatgcaatga tgtggtcttg
721 ttttggcgta tacagcgcat gcttgctatc accgcaaata ctttaaggca acaacttaca
781 aatactgaag ttaggcgatt agagaaaaat gttaaagagg tattggaaga ttttgctgaa
841 gatggtgaga agaagattaa attgcttact ggtaaacgcg ttcaactggc ggaagacctc
901 aagaaagtta gagaaattca agaaaaactt gatgctttca ttgaagctct tcatcaggag
961 aaataaatta aaatcgtact cataatcagc tctgcataca tctgaagaac aaaaacatca
1021 acgtcttttg tccagcctct ttttcttctg ctgttccacc tttctaaaca tacaataaag
1081 tcatgggata aaaataatcg atgtatgtta cgggcgcttt aaccatcagc tgcctctcga
1141 atggaagaac agtggtaatg gattaacatc ctattttgtt gtactaaagt gacaaatcgg
1201 aataatataa ttggtatggc cattaggttc agtccttgaa gataagaaac ttgttctctg
1261 tttgttgtct tatttgtggt ggcactcgtt taatggatta actgaggttg ctcaatgttc
1321 agtttctttt ccagaaatac aatgctaggt gttttgaaat aaaacttata tagcaattgt
1381 ttaaagttat caattgtata taaaatcaca gtagcctgta aaaaaaaaaa aaaaaaaaaa
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