LOCUS BC058004 1700 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens claudin 8, mRNA (cDNA clone MGC:61830 IMAGE:4606880),
complete cds.
ACCESSION BC058004
VERSION BC058004.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1700)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1700)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-SEP-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 48 Row: d Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40788010.
FEATURES Location/Qualifiers
source 1..1700
/db_xref="H-InvDB:HIT000259794"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61830 IMAGE:4606880"
/tissue_type="Kidney"
/clone_lib="NIH_MGC_75"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1700
/gene="CLDN8"
/db_xref="GeneID:9073"
/db_xref="HGNC:HGNC:2050"
CDS 76..753
/gene="CLDN8"
/codon_start=1
/product="claudin 8"
/protein_id="AAH58004.1"
/db_xref="GeneID:9073"
/db_xref="HGNC:HGNC:2050"
/translation="MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFE
NFWEGLWMNCVRQANIRMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGM
KCTRCTGDNEKVKAHILLTAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRE
LGEALYLGWTTALVLIVGGALFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSV
YSRSQYV"
BASE COUNT 522 a 297 c 354 g 527 t
ORIGIN
1 gggacagaga accctgcttc aaagcagaag tagcagttcc ggagtccagc tggctaaaac
61 tcatcccaga ggataatggc aacccatgcc ttagaaatcg ctgggctgtt tcttggtggt
121 gttggaatgg tgggcacagt ggctgtcact gtcatgcctc agtggagagt gtcggccttc
181 attgaaaaca acatcgtggt ttttgaaaac ttctgggaag gactgtggat gaattgcgtg
241 aggcaggcta acatcaggat gcagtgcaaa atctatgatt ccctgctggc tctttctccg
301 gacctacagg cagccagagg actgatgtgt gctgcttccg tgatgtcctt cttggctttc
361 atgatggcca tccttggcat gaaatgcacc aggtgcacgg gggacaatga gaaggtgaag
421 gctcacattc tgctgacggc tggaatcatc ttcatcatca cgggcatggt ggtgctcatc
481 cctgtgagct gggttgccaa tgccatcatc agagatttct ataactcaat agtgaatgtt
541 gcccaaaaac gtgagcttgg agaagctctc tacttaggat ggaccacggc actggtgctg
601 attgttggag gagctctgtt ctgctgcgtt ttttgttgca acgaaaagag cagtagctac
661 agatactcga taccttccca tcgcacaacc caaaaaagtt atcacaccgg aaagaagtca
721 ccgagcgtct actccagaag tcagtatgtg tagttgtgta tgttttttta actttactat
781 aaagccatgc aaatgacaaa aatctatatt actttctcaa aatggacccc aaagaaactt
841 tgatttactg ttcttaactg cctaatctta attacaggaa ctgtgcatca gctatttatg
901 attctataag ctatttcagc agaatgagat attaaaccca atgctttgat tgttctagaa
961 agtatagtaa tttgttttct aaggtggttc aagcatctac tctttttatc atttacttca
1021 aaatgacatt gctaaagact gcattatttt actactgtaa tttctccacg acatagcatt
1081 atgtacatag atgagtgtaa catttatatc tcacatagag acatgcttat atggttttat
1141 ttaaaatgaa atgccagtcc attacactga ataaatagaa ctcaactatt gcttttcagg
1201 gaaatcatgg atagggttga agaaggttac tattaattgt ttaaaaacag cttagggatt
1261 aatgtcctcc atttataatg aagattaaaa tgaaggcttt aatcagcatt gtaaaggaaa
1321 ttgaatggct ttctgatatg ctgtttttta gcctaggagt tagaaatcct aacttcttta
1381 tcctcttctc ccagaggctt tttttttctt gtgtattaaa ttaacatttt taaaaagcag
1441 atattttgtc aaggggcttt gcattcaaac tgcttttcca gggctatact cagaagaaag
1501 ataaaagtgt gatctaagaa aaagtgatgg ttttaggaaa gtgaaaatat ttttgttttt
1561 gtatttgaag aagaatgatg cattttgaca agaaatcata tatgtatgga tatattttaa
1621 taagtatttg agtacagact ttgaggtttc atcaatataa ataaaagagc agaaaaataa
1681 aaaaaaaaaa aaaaaaaaaa
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