LOCUS BC057795 2376 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens cancer susceptibility candidate 1, mRNA (cDNA clone
MGC:71648 IMAGE:5266518), complete cds.
ACCESSION BC057795
VERSION BC057795.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2376)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2376)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-SEP-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: m Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41350207.
FEATURES Location/Qualifiers
source 1..2376
/db_xref="H-InvDB:HIT000259733"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71648 IMAGE:5266518"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2376
/gene="CASC1"
/gene_synonym="FLJ10921"
/gene_synonym="LAS1"
/db_xref="GeneID:55259"
/db_xref="HGNC:HGNC:29599"
CDS 83..2233
/gene="CASC1"
/gene_synonym="FLJ10921"
/gene_synonym="LAS1"
/codon_start=1
/product="CASC1 protein"
/protein_id="AAH57795.1"
/db_xref="GeneID:55259"
/db_xref="HGNC:HGNC:29599"
/translation="MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERL
EIQRIEKEKWHRLEAKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCD
GSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDK
NIIQYQESILQLQELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWAN
LKKNPRHRSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSA
VTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEE
SEAIKCEREMKVLSETVSAAQLLLVENSSEKPDFFEDNVVDLCQFTTLGGVYHLDILE
LPPQCKPVKGWMIVEILKEGLQKYTYPPETTEEFETENAFPPIEVTLEVHENVIFFED
PVVVRWDAEGKHWRTDGISNVSYKPKERLVTFSLDTFGPVTLIQDAHINMPYQSWELR
PLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIKLKDKKHISILEGTWMTPIPFIIALK
EAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMALLSSAFAFGWSKWNLLCNSTKVVF
KVREHLTEECTENPNWALLMFSGDRAQRLKIKEESEAFSEALKEETEFHSTLYHMVKD
FASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS"
BASE COUNT 834 a 401 c 515 g 626 t
ORIGIN
1 gtcgcccggg caacccggga gcgtttgtcc acacaatttc tgctccgact ctgcggacta
61 ctgcagtgga gcttgactct taatgtctgg cagtaagaaa aagaaagtca ccaaagctga
121 acgattgaag ctgctacaag aggaggagga gagacgactg aaagaggaag aggaagcccg
181 tttgaaatat gagaaagaag aaatggaaag gcttgaaata cagcgaattg agaaagaaaa
241 atggcatcga cttgaagcaa aagatctaga aaggagaaat gaagaacttg aagaacttta
301 tttattagag aggtgttttc ctgaagcaga gaaattgaaa caggaaacta aattgctttc
361 tcagtggaag cactacattc aatgtgatgg gagtcctgat ccttcagtag cccaagaaat
421 gaacacgttt attagtttgt ggaaagagaa aacaaatgag acttttgagg aagtgattga
481 gaagagtaaa gtagtgctaa atttaattga gaaattgaaa tttattttac tggaaactcc
541 accatgtgat ttgcaagata aaaatataat acagtaccaa gaatcaatac tacaactgca
601 ggagctcctt catcttaaat tcggtgtagc cacagaaata cttctcaaac aagctagtac
661 tttggcagat ctggacagtg gaaatatgga aaaagtcatt aaagatgaaa atgttactct
721 gtatgtgtgg gcaaacctca agaagaatcc aaggcacaga agtgttagat tctctgaaac
781 acaaattgga tttgagattc caaggatatt agcaacaagt gacattgctg tacgactcct
841 gcatacccac tatgatcatg tttctgcact gcaccctgtt tcaacaccat caaaagaata
901 cacttctgca gtaactgagc ttgtcaaaga tgatgttaag aatgtagaaa aagcaatcag
961 caaggaggtc gaagaagagt ccaaacaaca agaaagaggg tctcacttaa ttcaggagga
1021 agaaataaaa gttgaggagg aacaaggtga tattgaagtg aaaatgagtt ctgctgagga
1081 agaatctgaa gccataaaat gtgaacgaga gatgaaagta ttaagtgaaa ctgtttcagc
1141 agcacagttg ttgctggtag agaattcttc tgaaaagcca gatttctttg aagacaatgt
1201 ggtggattta tgccagttca caactctggg tggagtatac cacttggata ttttggagct
1261 tcctccacag tgtaaaccag tgaagggatg gatgattgtg gaaatactca aagaaggatt
1321 acagaaatac acatatcctc cggaaactac agaagagttt gagacagaaa atgctttccc
1381 acctatagag gtcacacttg aggttcatga gaatgtaatc ttttttgagg atcctgtggt
1441 tgtaaggtgg gatgctgaag gtaaacattg gagaactgat ggcatcagca atgtatccta
1501 caaaccaaaa gaaagacttg taacattcag cctggacacc tttggccctg ttaccttgat
1561 tcaagatgct catattaaca tgccgtacca gtcatgggaa ctaagaccac ttgatgtaaa
1621 taaagtactt ttaactgtga ctacagtatt tactgagatt caaatacaaa ttaaggaaaa
1681 cctctgcatg ttatcttcaa tcaaactaaa agacaagaaa cacatctcta ttttggaagg
1741 aacctggatg actcctattc ctttcattat tgctttgaaa gaagctggac tgaatatctt
1801 tcctactaga cactctcatt tttatgttat tataaacaat aaggttcctt tggtagaagt
1861 gaaagcttat cgacagatgg ccctactaag ttctgctttt gcatttggtt ggagcaagtg
1921 gaacctacta tgtaattcta caaaagtcgt atttaaggtg agggaacacc ttactgaaga
1981 atgtactgag aatcctaatt gggccctttt aatgtttagt ggtgacagag cacaaagact
2041 gaagatcaag gaagagagtg aggcattttc tgaagcactt aaagaagaaa ctgagtttca
2101 ttctacttta tatcacatgg tgaaggattt tgcttctgag gaagcaatgg agaaagtcag
2161 gagttccaac tgtcagtttg tcaactctgt gtgccacatg ctgctctcta ccagattgct
2221 cagctactcc taacctccac ttacaaactg tattgtaagt atgaagaacc aagcatggtg
2281 aaagacaggt atttctgcaa cacaatgtaa tgagtgaatg aatacatttc aaatcaacta
2341 ttaaaaattt tctaatctgc aaaaaaaaaa aaaaaa
//