LOCUS BC057228 1720 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens group-specific component (vitamin D binding protein),
mRNA (cDNA clone MGC:61910 IMAGE:4767205), complete cds.
ACCESSION BC057228
VERSION BC057228.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1720)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1720)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-AUG-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 48 Row: f Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32483409.
FEATURES Location/Qualifiers
source 1..1720
/db_xref="H-InvDB:HIT000259653"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61910 IMAGE:4767205"
/tissue_type="Liver"
/clone_lib="NIH_MGC_76"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1720
/gene="GC"
/gene_synonym="DBP"
/gene_synonym="DBP/GC"
/gene_synonym="VDBG"
/gene_synonym="VDBP"
/db_xref="GeneID:2638"
/db_xref="HGNC:HGNC:4187"
/db_xref="MIM:139200"
CDS 63..1487
/gene="GC"
/gene_synonym="DBP"
/gene_synonym="DBP/GC"
/gene_synonym="VDBG"
/gene_synonym="VDBP"
/codon_start=1
/product="group-specific component (vitamin D binding
protein)"
/protein_id="AAH57228.1"
/db_xref="GeneID:2638"
/db_xref="HGNC:HGNC:4187"
/db_xref="MIM:139200"
/translation="MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLS
LVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPF
PVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFM
WEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNR
VCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAK
ELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDV
CDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLL
KKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKRSDFAS
NCCSINSPPLYCDSEIDAELKNIL"
BASE COUNT 542 a 383 c 360 g 435 t
ORIGIN
1 ggggactttt acatggtcac ctataggaga gaggaggtgc tgcaagactc tctggtagaa
61 aaatgaagag ggtcctggta ctactgcttg ctgtggcatt tggacatgct ttagagagag
121 gccgggatta tgaaaagaat aaagtctgca aggaattctc ccatctggga aaggaggact
181 tcacatctct gtcactagtc ctgtacagta gaaaatttcc cagtggcacg tttgaacagg
241 tcagccaact tgtgaaggaa gttgtctcct tgaccgaagc ctgctgtgcg gaaggggctg
301 accctgactg ctatgacacc aggacctcag cactgtctgc caagtcctgt gaaagtaatt
361 ctccattccc cgttcaccca ggcactgctg agtgctgcac caaagagggc ctggaacgaa
421 agctctgcat ggctgctctg aaacaccagc cacaggaatt ccctacctac gtggaaccca
481 caaatgatga aatctgtgag gcgttcagga aagatccaaa ggaatatgct aatcaattta
541 tgtgggaata ttccactaat tacggacaag ctcctctgtc acttttagtc agttacacca
601 agagttatct ttctatggta gggtcctgct gtacctctgc aagcccaact gtatgctttt
661 tgaaagagag actccagctt aaacatttat cacttctcac cactctgtca aatagagtct
721 gctcacaata tgctgcttat ggggagaaga aatcaaggct cagcaatctc ataaagttag
781 cccaaaaagt gcctactgct gatctggagg atgttttgcc actagctgaa gatattacta
841 acatcctctc caaatgctgt gagtctgcct ctgaagattg catggccaaa gagctgcctg
901 aacacacagt aaaactctgt gacaatttat ccacaaagaa ttctaagttt gaagactgtt
961 gtcaagaaaa aacagccatg gacgtttttg tgtgcactta cttcatgcca gctgcccaac
1021 tccccgagct tccagatgta gagttgccca caaacaaaga tgtgtgtgat ccaggaaaca
1081 ccaaagtcat ggataagtat acatttgaac taagcagaag gactcatctt ccggaagtat
1141 tcctcagtaa ggtacttgag ccaaccctaa aaagccttgg tgaatgctgt gatgttgaag
1201 actcaactac ctgttttaat gctaagggcc ctctactaaa gaaggaacta tcttctttca
1261 ttgacaaggg acaagaacta tgtgcagatt attcagaaaa tacatttact gagtacaaga
1321 aaaaactggc agagcgacta aaagcaaaat tgcctgatgc cacacccacg gaactggcaa
1381 agctggttaa caagcgctca gactttgcct ccaactgctg ttccataaac tcacctcctc
1441 tttactgtga ttcagagatt gatgctgaat tgaagaatat cctgtagtcc tgaagcatgt
1501 ttattaactt tgaccagagt tggagccacc caggggaatg atctctgatg acctaaccta
1561 agcaaaacca ccgagcttct gggaagacaa ctaggatact ttctactttt tctagctaca
1621 atatcttcat acaatgacaa gtatgatgat ttgctatcaa aataaattga aatataatgc
1681 aaaccaaaaa aaaaaaaaaa aaaaaaaaaa aaaaacatgt
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