LOCUS BC054006 3847 bp mRNA linear HUM 08-OCT-2003
DEFINITION Homo sapiens epidermal growth factor receptor pathway substrate 15,
mRNA (cDNA clone MGC:61536 IMAGE:6164633), complete cds.
ACCESSION BC054006
VERSION BC054006.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3847)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3847)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (24-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: n Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503592.
FEATURES Location/Qualifiers
source 1..3847
/db_xref="H-InvDB:HIT000054046"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61536 IMAGE:6164633"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3847
/gene="EPS15"
/gene_synonym="AF-1P"
/gene_synonym="AF1P"
/gene_synonym="MLLT5"
/db_xref="GeneID:2060"
/db_xref="MIM:600051"
CDS 11..2299
/gene="EPS15"
/gene_synonym="AF-1P"
/gene_synonym="AF1P"
/gene_synonym="MLLT5"
/codon_start=1
/product="EPS15 protein"
/protein_id="AAH54006.1"
/db_xref="GeneID:2060"
/db_xref="MIM:600051"
/translation="MAAAAQLSLTQLSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLK
KSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVSLSSLNLAVPPPR
FHDTSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKL
PVDILGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTW
VVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGK
LSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPSDRASLQKNIIGSSPVADFSAIKE
LDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ
QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLARSSPELLPSGVTDENEVTTAVTEK
VCSELDNNRHSKEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDDPFGKIDPF
GGDPFKGSDPFASDCFFRQSTDPFATSSTDPFSAANNSSITSVETLKHNDPFAPGGTV
VAASDSATDPFASVFGNESFGGGFADFSTLSKVNNEDPFRSATSSSVSNVVITKNVFE
ETSVKSEDEPPALPPKIGTPTRPCPLPPGKRSINKLDSPDPFKLNDPFQPFPGNDSPK
EKDPEMFCDPFTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKRESEREEEQRLARL
NQQEQEDLELAIALSKSEISEA"
misc_feature 56..319
/gene="EPS15"
/gene_synonym="AF-1P"
/gene_synonym="AF1P"
/gene_synonym="MLLT5"
/note="EH; Region: Eps15 homology domain"
/db_xref="CDD:smart00027"
misc_feature 371..655
/gene="EPS15"
/gene_synonym="AF-1P"
/gene_synonym="AF1P"
/gene_synonym="MLLT5"
/note="EH; Region: Eps15 homology domain"
/db_xref="CDD:smart00027"
misc_feature 662..949
/gene="EPS15"
/gene_synonym="AF-1P"
/gene_synonym="AF1P"
/gene_synonym="MLLT5"
/note="EH; Region: Eps15 homology domain"
/db_xref="CDD:smart00027"
BASE COUNT 1246 a 702 c 763 g 1136 t
ORIGIN
1 tggaaacacc atggctgcgg cggcccagct ctctctgaca cagttatcaa gtgggaatcc
61 tgtatatgaa aaatactata gacaggttga tacaggcaat actggaaggg tgttggcttc
121 tgatgctgct gctttcctga aaaaatcagg gcttccagac ttgatacttg gaaagatttg
181 ggatttagcc gacacagatg gcaaaggtat cctgaacaaa caagaattct ttgttgcttt
241 gcgtcttgtg gcatgtgccc agaatggatt ggaagtttca ctaagtagtt tgaacctggc
301 tgttcctcca ccaagatttc atgataccag tagtcctttg ctaatcagtg gaacctctgc
361 agctgagctc ccatgggctg taaaacctga agataaggcc aaatatgatg caatatttga
421 tagtttaagc ccagtgaatg gatttctgtc tggtgataaa gtgaaaccag tgttgctcaa
481 ctctaagtta cctgtggata tccttggaag agtttgggag ttgagtgata ttgaccatga
541 tggaatgctt gacagagatg agtttgcagt tgctatgttt ttggtatact gtgcactgga
601 gaaagaacct gtgccaatgt ccttgcctcc agccttggtg ccaccatcta agagaaaaac
661 gtgggttgta tcccctgcag aaaaagctaa atatgatgaa atcttcctga aaactgataa
721 agatatggac ggatttgtgt ctggattgga ggtccgtgaa atattcttga aaacaggttt
781 accttctacc ttactagccc atatatggtc attatgcgac acaaaggact gtgggaagct
841 ttcaaaggat cagtttgcct tggcttttca cttaatcagt cagaagttaa tcaagggcat
901 tgatcctcct cacgttctta ctcctgaaat gattccacca tcagacaggg ccagtttaca
961 aaagaacatc ataggatcaa gtcctgttgc agatttctct gctattaagg aactagatac
1021 tcttaacaat gaaatagttg acctacagag ggaaaagaat aatgtggaac aggaccttaa
1081 ggagaaggaa gatactatta aacagaggac aagtgaggtt caggatcttc aagatgaagt
1141 tcaaagggag aatactaatc tgcaaaaact acaggcccag aaacagcagg tacaggaact
1201 ccttgatgaa ctggatgagc agaaagccca gctggaggag caactcaagg aagtcagaaa
1261 gaaatgtgct gaggaggccc aactggcaag aagtagtcct gaactactgc cttctggtgt
1321 gactgatgaa aatgaggtga ctacagctgt tactgaaaaa gtttgttctg aactcgacaa
1381 taatagacat tcaaaagagg aagatccatt taatgtagac tcaagttcgc tgacaggtcc
1441 agttgcagat acaaacttgg attttttcca gtctgatcct tttgttggca gtgatccttt
1501 caaggatgat ccttttggaa aaatcgatcc atttggtggt gatcctttca aaggttcaga
1561 tccatttgca tcagactgtt tcttcaggca atctactgat ccttttgcca cttcaagcac
1621 tgaccctttc agtgcagcca acaatagcag tattacatcg gtagaaacgt tgaagcacaa
1681 tgatcctttt gctcctggtg gaacagttgt tgcagcaagc gattcagcca cagacccctt
1741 tgcttctgtt tttgggaatg aatcatttgg aggtggattt gctgacttca gcacattgtc
1801 aaaggtcaac aatgaagatc cttttcgttc agccacatcg agctctgtca gcaacgtagt
1861 gattacaaaa aatgtatttg aggaaacatc ggtcaaaagt gaagatgaac ccccagcact
1921 gccaccaaag atcggaactc caacaagacc ctgccctcta ccacctggga aaagatccat
1981 caacaaattg gattctcctg atccctttaa actgaatgat ccatttcagc ctttcccagg
2041 caacgatagc cccaaagaaa aagatcctga aatgttttgt gatccattca cttctgctac
2101 taccactacc aataaagagg ctgatccaag caattttgcc aacttcagtg cttatccctc
2161 tgaagaagat atgatcgaat gggccaagag ggaaagtgag agagaggaag agcagaggct
2221 tgcccgacta aatcagcagg aacaagaaga cttagaactg gctattgcac tcagcaaatc
2281 tgagatatca gaagcatgaa gaattctctt gttctttggc aacaatatag tattcttctt
2341 cctgaatact gaaactattt acaatgtgta tcaaaactac ctgtgagcat gggaatacaa
2401 aaggtttgag attcctgtaa atgtgacaaa attttaggat tttttttttt cttcattaca
2461 gattcgtctt tttttttttt cttataaaag ccgtaaccca gtcagacaaa ttcaccttca
2521 cttaggcccc tgttctggta tacatttact gtgagctttt gcctgcctgt gctattttac
2581 ttgtaaagct agagcaccca agcttctgcc ttctggaata tagagaaata gtttcaccct
2641 gcactaccct gttctgtagt tattctgatg atagccagtg aggttcttaa agtttgcagt
2701 attctcccct gattggaatg gttgagtgag ggtaagggaa agaatatctt atttctttta
2761 tgattggtgc aaattggcta aagtgcattt ttaaatttcc tctacttaat ttgtttttca
2821 gagataagga aaaatatttt gcacagattt actccactat ggaaaaggga tgctgtaggt
2881 tgaaccatta tagcctcaga ttcgatcttt tcctaactaa aaatattaaa gcctcatgtg
2941 tgaaataaat ttttaaaaag atttatctgg atttagagaa ttttagatca acagatacct
3001 ctcagtgtgt ttgctaatta ataaaaatca gtttcttaca aataaagttt gtaagaaaat
3061 gttcatttta agtgatagat agtggagaaa atttatcacc taaaatatac ccatcagtat
3121 aaggcaagca aaagtcttaa catggcagcc attctgcctt tgccgtggcc ctgtcctgtt
3181 tagttcttag tgggttaatt tttgtacttt tgcagaagaa acttcagcaa gctagaactg
3241 gaaggtactt taatttttca tatatatttg tttttttttt tttaatgaag gctcatttac
3301 ttgaaatgta aaaactttca ctgaatacaa atagaaaaag tgatgtgttt tatatcatat
3361 tgctttttgt ccatctttgt ggtttagttt atttactcac ttcatgtttt tcacctataa
3421 aattgtcaag ctagcaaaaa aaactcttgt ttttttaatt gggagagaag agacctgcca
3481 gattatcaga cctcttcatg ttaaaagacc atctcctgta aaactgacct agtggacaag
3541 ctgaatttga aatagactgt gaagtaagct gtaactgtca ttttaatttt gtttaacacg
3601 gttactgact tagatgatgt attaaatacc aagataaaga aaaatgcacc taaaatctaa
3661 ttagaattct ctgggtcacc aagtcaaggt ggtattgatc tgtgttaatc tgagtaactt
3721 attgcctagc ctataaataa attccaaaat aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3781 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3841 aaaaaaa
//