LOCUS BC054000 3527 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens interleukin-1 receptor-associated kinase 1, mRNA (cDNA
clone MGC:61493 IMAGE:6164719), complete cds.
ACCESSION BC054000
VERSION BC054000.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3527)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3527)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (24-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: n Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4755143.
FEATURES Location/Qualifiers
source 1..3527
/db_xref="H-InvDB:HIT000054040"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61493 IMAGE:6164719"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3527
/gene="IRAK1"
/gene_synonym="IRAK"
/gene_synonym="pelle"
/db_xref="GeneID:3654"
/db_xref="MIM:300283"
CDS 79..2160
/gene="IRAK1"
/gene_synonym="IRAK"
/gene_synonym="pelle"
/codon_start=1
/product="IRAK1 protein"
/protein_id="AAH54000.1"
/db_xref="GeneID:3654"
/db_xref="MIM:300283"
/translation="MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQ
FGGWRRAAGGREARGLLAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINR
NARVADLVHILTHLQLLRARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRK
LPSSASTFLSPAFPGSQTHSGPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQG
ARPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWT
AVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACP
PLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSR
FAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAV
KTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLGQLA
CCCLHRRAKRRPPMTQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQP
VESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVE
GLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDR
QGPEESDEFQS"
misc_feature 805..1419
/gene="IRAK1"
/gene_synonym="IRAK"
/gene_synonym="pelle"
/note="pkinase; Region: Protein kinase domain"
/db_xref="CDD:pfam00069"
BASE COUNT 700 a 1091 c 1115 g 621 t
ORIGIN
1 gcggacccgg ccggcccagg cccgcgcccg ccgcggccct gagaggcccc ggcaggtccc
61 ggcccggcgg cggcagccat ggccgggggg ccgggcccgg gggagcccgc agcccccggc
121 gcccagcact tcttgtacga ggtgccgccc tgggtcatgt gccgcttcta caaagtgatg
181 gacgccctgg agcccgccga ctggtgccag ttcggtgggt ggcggcgggc tgccgggggg
241 cgggaggcgc gcgggctcct ggcgccgacg cctgacgccc cccgccccgc agccgccctg
301 atcgtgcgcg accagaccga gctgcggctg tgcgagcgct ccgggcagcg cacggccagc
361 gtcctgtggc cctggatcaa ccgcaacgcc cgtgtggccg acctcgtgca catcctcacg
421 cacctgcagc tgctccgtgc gcgggacatc atcacagcct ggcaccctcc cgccccgctt
481 ccgtccccag gcaccactgc cccgaggccc agcagcatcc ctgcacccgc cgaggccgag
541 gcctggagcc cccggaagtt gccatcctca gcctccacct tcctctcccc agcttttcca
601 ggctcccaga cccattcagg gcctgagctc ggcctggtcc caagccctgc ttccctgtgg
661 cctccaccgc catctccagc cccttcttct accaagccag gcccagagag ctcagtgtcc
721 ctcctgcagg gagcccgccc ctttccgttt tgctggcccc tctgtgagat ttcccggggc
781 acccacaact tctcggagga gctcaagatc ggggagggtg gctttgggtg cgtgtaccgg
841 gcggtgatga ggaacacggt gtatgctgtg aagaggctga aggagaacgc tgacctggag
901 tggactgcag tgaagcagag cttcctgacc gaggtggagc agctgtccag gtttcgtcac
961 ccaaacattg tggactttgc tggctactgt gctcagaacg gcttctactg cctggtgtac
1021 ggcttcctgc ccaacggctc cctggaggac cgtctccact gccagaccca ggcctgccca
1081 cctctctcct ggcctcagcg actggacatc cttctgggta cagcccgggc aattcagttt
1141 ctacatcagg acagccccag cctcatccat ggagacatca agagttccaa cgtccttctg
1201 gatgagaggc tgacacccaa gctgggagac tttggcctgg cccggttcag ccgctttgcc
1261 gggtccagcc ccagccagag cagcatggtg gcccggacac agacagtgcg gggcaccctg
1321 gcctacctgc ccgaggagta catcaagacg ggaaggctgg ctgtggacac ggacaccttc
1381 agctttgggg tggtagtgct agagaccttg gctggtcaga gggctgtgaa gacgcacggt
1441 gccaggacca agtatctgaa agacctggtg gaagaggagg ctgaggaggc tggagtggct
1501 ttgagaagca cccagagcac actgcaagca ggtctggctg cagatgcctg ggctgctccc
1561 atcgccatgc agatctacaa gaagcacctg ggccagctgg cctgctgctg cctgcaccgc
1621 cgggccaaaa ggaggcctcc tatgacccag gagaactcct acgtgtccag cactggcaga
1681 gcccacagtg gggctgctcc atggcagccc ctggcagcgc catcaggagc cagtgcccag
1741 gcagcagagc agctgcagag aggccccaac cagcccgtgg agagtgacga gagcctaggc
1801 ggcctctctg ctgccctgcg ctcctggcac ttgactccaa gctgccctct ggacccagca
1861 cccctcaggg aggccggctg tcctcagggg gacacggcag gagaatcgag ctgggggagt
1921 ggcccaggat cccggcccac agccgtggaa ggactggccc ttggcagctc tgcatcatcg
1981 tcgtcagagc caccgcagat tatcatcaac cctgcccgac agaagatggt ccagaagctg
2041 gccctgtacg aggatggggc cctggacagc ctgcagctgc tgtcgtccag ctccctccca
2101 ggcttgggcc tggaacagga caggcagggg cccgaagaaa gtgatgaatt tcagagctga
2161 tgtgttcacc tgggcagatc ccccaaatcc ggaagtcaaa gttctcatgg tcagaagttc
2221 tcatggtgca cgagtcctca gcactctgcc ggcagtgggg gtgggggccc atgcccgcgg
2281 gggagagaag gaggtggccc tgctgttcta ggctctgtgg gcataggcag gcagagtgga
2341 accctgcctc catgccagca tctgggggca aggaaggctg gcatcatcca gtgaggaggc
2401 tggcgcatgt tgggaggctg ctggctgcac agacccgtga ggggaggaga ggggctgctg
2461 tgcaggggtg tggagtaggg agctggctcc cctgagagcc atgcagggcg tctgcagccc
2521 aggcctctgg cagcagctct ttgcccatct ctttggacag tggccaccct gcacaatggg
2581 gccgacgagg cctagggccc tcctacctgc ttacaatttg gaaaagtgtg gccgggtgcg
2641 gtggctcacg cctgtaatcc cagcactttg ggaggccaag gcaggaggat cgctggagcc
2701 cagtaggtca agaccagcca gggcaacatg atgagaccct gtctctgcca aaaaattttt
2761 taaactatta gcctggcgtg gtagcgcacg cctgtggtcc cagctgctgg ggaggctgaa
2821 gtaggaggat catttatgct tgggaggtcg aggctgcagt gagtcatgat tgtatgactg
2881 cactccagcc tgggtgacag agcaagaccc tgtttcaaaa agaaaaaccc tgggaaaagt
2941 gaagtatggc tgtaagtctc atggttcagt cctagcaaga agcgagaatt ctgagatcct
3001 ccagaaagtc gagcagcacc cacctccaac ctcgggccag tgtcttcagg ctttactggg
3061 gacctgcgag ctggcctaat gtggtggcct gcaagccagg ccatccctgg gcgccacaga
3121 cgagctccga gccaggtcag gcttcggagg ccacaagctc agcctcaggc ccaggcactg
3181 attgtggcag aggggccact acccaaggtc tagctaggcc caagacctag ttacccagac
3241 agtgagaagc ccctggaagg cagaaaagtt gggagcatgg cagacaggga agggaaacat
3301 tttcagggaa aagacatgta tcacatgtct tcagaagcaa gtcaggtttc atgtaaccga
3361 gtgtcctctt gcgtgtccaa aagtagccca gggctgtagc acaggcttca cagtgatttt
3421 gtgttcagcc gtgagtcaca ctacatgccc ccgtgaagct gggcattggt gacgtccagg
3481 ttgtccttga gtaataaaaa cgtatgttgc aaaaaaaaaa aaaaaaa
//