LOCUS BC053658 2390 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens copine II, mRNA (cDNA clone MGC:61692 IMAGE:5750192),
complete cds.
ACCESSION BC053658
VERSION BC053658.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2390)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2390)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (09-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: h Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 25141319.
FEATURES Location/Qualifiers
source 1..2390
/db_xref="H-InvDB:HIT000053962"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61692 IMAGE:5750192"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2390
/gene="CPNE2"
/gene_synonym="COPN2"
/gene_synonym="CPN2"
/gene_synonym="MGC16924"
/db_xref="GeneID:221184"
/db_xref="MIM:604206"
CDS 358..2004
/gene="CPNE2"
/gene_synonym="COPN2"
/gene_synonym="CPN2"
/gene_synonym="MGC16924"
/codon_start=1
/product="CPNE2 protein"
/protein_id="AAH53658.1"
/db_xref="GeneID:221184"
/db_xref="MIM:604206"
/translation="MAHIPSGGAPAAGAAPMGPQYCVCKVELSVSGQNLLDRDVTSKS
DPFCVLFTENNGRWIEYDRTETAINNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSS
MRLDEHDFLGQFSCSLGTIVSSKKITRPLLLLNDKPAGKGLITIAAQELSDNRVITLS
LAGRRLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLC
DGDMEKPIQVMCYDYDNDGGHDFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKN
YKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMG
TNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVD
GIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDM
EETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPF
REFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA"
misc_feature 445..702
/gene="CPNE2"
/gene_synonym="COPN2"
/gene_synonym="CPN2"
/gene_synonym="MGC16924"
/note="C2; Region: C2 domain"
/db_xref="CDD:pfam00168"
misc_feature 838..1119
/gene="CPNE2"
/gene_synonym="COPN2"
/gene_synonym="CPN2"
/gene_synonym="MGC16924"
/note="C2; Region: Protein kinase C conserved region 2
(CalB)"
/db_xref="CDD:smart00239"
misc_feature 1354..1875
/gene="CPNE2"
/gene_synonym="COPN2"
/gene_synonym="CPN2"
/gene_synonym="MGC16924"
/note="VWA; Region: von Willebrand factor (vWF) type A
domain"
/db_xref="CDD:smart00327"
BASE COUNT 563 a 711 c 631 g 485 t
ORIGIN
1 cggaccccga gcggctggga gcgcacgcga gcgggccgtg gccgcgcggg cagcgccctg
61 agcctgtccc gcgcccgcgg gcccggccga gcaggagcag ctcccgggga tgcccgggcg
121 gctcggagcg cgggcagcgg cagccgtgcg gtgagggcgg tggcgcccgc gggacctgcg
181 ggaacttggc ccagaccctc cgcccctgtg gccctctggg tcaccatctg tgaaatgggc
241 tgatgttccg gggcctgcct cctggagaat ggacacagca tgaaggcgtg gttttatggc
301 attccgcctg gcataggtcc agactgccag gaactcctgc caccgccacc ggctcccatg
361 gcccacatac ccagtggggg tgccccagca gcgggggcag cccccatggg cccccagtat
421 tgcgtgtgca aggtggagct gtcagtgagt ggccagaacc tactggaccg ggatgttacc
481 tccaagtccg accccttctg tgtcctcttt acagagaaca atggcagatg gatcgagtac
541 gacaggacag aaaccgcgat caacaacctc aaccccgcct tctccaagaa gttcgtgctt
601 gactaccact tcgaggaggt acagaagctc aagttcgcgc tctttgacca ggacaagtcc
661 agtatgcggc tggacgagca tgacttcctg ggccagttct cctgcagcct gggcacgatc
721 gtctccagca agaagatcac taggcctctg ctgctgctga atgacaagcc tgcggggaag
781 ggcttgatta cgatcgctgc ccaggagctg tccgacaacc gcgtcatcac actaagcctg
841 gcgggcagga ggctggacaa gaaggacctc tttgggaagt cagacccctt tctggagttt
901 tataagccag gagacgatgg caagtggatg ctggtccaca ggactgaggt gatcaagtac
961 acactggacc ctgtgtggaa gccattcaca gtgcccttgg tgtccctgtg tgatggggac
1021 atggagaagc ccatccaggt catgtgctac gactatgaca atgacggggg ccatgacttc
1081 atcggcgagt tccagacctc agtgtcacag atgtgtgagg ctcgagacag cgtcccgctg
1141 gagttcgagt gcatcaaccc caagaagcag aggaagaaga agaactataa aaactcgggc
1201 atcatcatcc tgcgatcctg caagataaac cgagactact ccttccttga ctacatcctg
1261 ggaggctgcc agctcatgtt caccgttgga atagacttta cagcctccaa cgggaatccc
1321 ctcgaccctt cctctttgca ctatatcaac cctatgggca ccaacgaata tctgtcggcc
1381 atctgggctg ttgggcagat cattcaggac tacgacagtg ataagatgtt tccagctctg
1441 ggattcgggg cccagttacc cccagactgg aaggtctccc atgagtttgc catcaacttc
1501 aaccccacca accccttctg ctcaggtgtg gatggtattg cccaggcgta ctcagcttgc
1561 ctgccccaca tccgcttcta cggtcctacc aatttctccc ccatcgtcaa ccacgtggcc
1621 cggtttgcgg cccaggccac acaacagcgg acggccacgc agtacttcat cctcctcatc
1681 atcacggacg gggtcatcag tgacatggag gagacacggc atgccgtggt gcaggcttcc
1741 aagctgccca tgtccatcat catcgtgggc gtgggcaatg cggacttcgc tgccatggag
1801 ttcctggatg gggacagccg catgctgcgc tcccacacgg gggaggaggc agcccgcgat
1861 attgtgcagt tcgttccctt tcgagagttc cgcaacgcag caaaagagac cttggccaaa
1921 gctgtgctgg cggagctgcc ccaacaagtt gtgcagtatt tcaagcataa aaacctgccc
1981 cccaccaact cggagcccgc ctgagctcca gtgcccagca gcagcatgtc agctgagcct
2041 cctgccctcc cccaggaaca tgcacgctca ctctgcttcc ttgtgggtgg ccttttttta
2101 ccgatcccct tttttatttt ttacaaccgg acctccaccc ccaacttcct ccagcccagc
2161 tgggcttcct ttgttggagt caactgttga tgcttccagg ccaaactggc ttcctctcct
2221 cctctcccca cctttgccat tcttaagtat tgaatgtact ttgtataatt ttagtggaat
2281 tgttattgag aataaaattt ttacaatcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2341 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//