LOCUS BC053366 1750 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens membrane protein, palmitoylated 5 (MAGUK p55 subfamily
member 5), mRNA (cDNA clone IMAGE:6142510), partial cds.
ACCESSION BC053366
VERSION BC053366.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1750)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1750)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: k Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, Similarity but not identity to protein.
FEATURES Location/Qualifiers
source 1..1750
/db_xref="H-InvDB:HIT000259263"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6142510"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..>1750
/gene="MPP5"
/gene_synonym="FLJ12615"
/gene_synonym="PALS1"
/db_xref="GeneID:64398"
/db_xref="MIM:606958"
CDS 411..>1750
/gene="MPP5"
/gene_synonym="FLJ12615"
/gene_synonym="PALS1"
/codon_start=1
/product="MPP5 protein"
/protein_id="AAH53366.1"
/db_xref="GeneID:64398"
/db_xref="MIM:606958"
/translation="MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLG
TRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP
MFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQ
NAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQ
ALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD
SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP
SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA
YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKKK"
misc_feature 783..947
/gene="MPP5"
/gene_synonym="FLJ12615"
/gene_synonym="PALS1"
/note="L27; Region: domain in receptor targeting proteins
Lin-2 and Lin-7"
/db_xref="CDD:smart00569"
misc_feature 966..1121
/gene="MPP5"
/gene_synonym="FLJ12615"
/gene_synonym="PALS1"
/note="L27; Region: domain in receptor targeting proteins
Lin-2 and Lin-7"
/db_xref="CDD:smart00569"
misc_feature 1170..1412
/gene="MPP5"
/gene_synonym="FLJ12615"
/gene_synonym="PALS1"
/note="PDZ; Region: PDZ domain, PSD95(post synaptic
density protein) DlgA (Drosophila disc large tumor
suppressor) ZO1, a mammalian tight junction protein
domain"
/db_xref="CDD:cd00136"
misc_feature 1455..1649
/gene="MPP5"
/gene_synonym="FLJ12615"
/gene_synonym="PALS1"
/note="SH3; Region: Src homology 3 domains"
/db_xref="CDD:cd00174"
BASE COUNT 565 a 310 c 442 g 433 t
ORIGIN
1 cggcgacgga ggaggcaggc ggtggggcgg gggcggggac taaggattct gaggtgggga
61 gtcgggagtt tctggattct ttatccggaa tttcaagggc cgccggaggg ctgtcgcttc
121 tgcagtgcgt aggagcggcc ggggcgggag gctccgcgga gccgaggcgt ggagaataag
181 aaagccttga gttttgtgaa aaaccggaga agagaaacta aaaggacagt agaaaaggct
241 tttccagttt gcataatatt tccttcatgg atactttttc atagcattat tatgtgatgt
301 gagaagtttt tttttttgaa gtaacatgga ttttatacta cagaatcaag agaattggct
361 tataggaaaa attgatttat aaaaagtggt acaggttttc atagataacc atgacaacat
421 cccatatgaa tgggcatgtt acagaggaat cagacagcga agtaaaaaat gttgatcttg
481 catcaccaga ggaacatcag aagcaccgag agatggctgt tgactgccct ggagatttgg
541 gcaccaggat gatgccaata cgtcgaagtg cacagttgga gcgtattcgg caacaacagg
601 aggacatgag gcgtaggaga gaggaagaag ggaaaaagca agaacttgac cttaattctt
661 ccatgagact taagaaacta gcccaaattc ctccaaagac cggaatagat aaccctatgt
721 ttgatacaga ggaaggaatt gtcttagaaa gtcctcatta tgctgtgaaa atattagaaa
781 tagaagactt gttttcttca cttaaacata tccaacatac tttggtagat tctcagagcc
841 aggaggatat ttcactgctt ttacaacttg ttcaaaataa ggatttccag aatgcattta
901 agatacacaa tgccatcaca gtacacatga acaaggccag tcctccattt cctcttatct
961 ccaacgcaca agatcttgct caagaggtac aaactgtttt gaagccagtt catcataagg
1021 aaggacaaga actaactgct ttgctgaata ctccacatat tcaggcactt ttactggccc
1081 acgataaggt tgctgagcag gaaatgcagc tagagcccat tacagatgag agagtttatg
1141 aaagtattgg ccagtatgga ggagaaactg taaaaatagt tcgtatagaa aaggctcgtg
1201 atattccgtt gggtgctaca gttcgtaatg aaatggactc tgtcatcatt agccggatag
1261 taaaaggggg tgctgcagag aaaagtggtc tgttgcatga aggagatgaa gttctagaga
1321 ttaatggcat tgaaattcgg gggaaagatg tcaatgaggt ttttgacttg ttgtctgata
1381 tgcatggtac tttgactttt gtcctgattc ccagtcaaca gatcaagccg cctcctgcca
1441 aggaaacagt aatccatgta aaagctcatt ttgactatga cccctcagat gacccttatg
1501 ttccatgtcg agagttaggt ctgtcttttc aaaaaggtga tatacttcat gtgatcagtc
1561 aagaagatcc aaactggtgg caggcctaca gggaagggga cgaagataat caacctctag
1621 ccgggcttgt tccagggaaa agctttcagc agcaaaggga agccatgaaa caaaccatag
1681 aagaagataa ggagccagaa aaatcaggaa aactgtggtg tgcaaagaag aataaaaaaa
1741 aaaaaaaaaa
//