LOCUS BC052998 3263 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens discoidin domain receptor tyrosine kinase 2, mRNA
(cDNA clone MGC:60389 IMAGE:6162716), complete cds.
ACCESSION BC052998
VERSION BC052998.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3263)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3263)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC052998.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: l Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62420883.
FEATURES Location/Qualifiers
source 1..3263
/db_xref="H-InvDB:HIT000053868"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60389 IMAGE:6162716"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3263
/gene="DDR2"
/gene_synonym="MIG20a"
/gene_synonym="TKT"
/db_xref="GeneID:4921"
/db_xref="HGNC:HGNC:2731"
/db_xref="MIM:191311"
CDS 437..3004
/gene="DDR2"
/gene_synonym="MIG20a"
/gene_synonym="TKT"
/codon_start=1
/product="discoidin domain receptor tyrosine kinase 2"
/protein_id="AAH52998.1"
/db_xref="GeneID:4921"
/db_xref="HGNC:HGNC:2731"
/db_xref="MIM:191311"
/translation="MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDE
DITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGT
QGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIV
ARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYD
GAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFD
RIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFV
TVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLK
VDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSD
SSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVK
PVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFK
EKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLK
EIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTV
SYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDY
YRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVI
ENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE"
BASE COUNT 840 a 822 c 781 g 820 t
ORIGIN
1 cgacccacgc gtccggcctg tggatgtatg cctaccaccg ggctccttca ccagcaaagt
61 ggaaaaagaa gcgtttcaca acaaattctt ctttttgggt tggggaaacg cagtggatta
121 tagctctgtt ttcttctttc caaaactgtg cacccctgga tgaaacctcc atcaagggag
181 acctacaagt tgcctggggt tcagtgctct agaaagttcc aaggtttgtg gcttgaatta
241 ttctaaagaa gctgaaataa ttgaagagaa gcagaggcca gctgtttttg aggatcctgc
301 tccacagaga atgctctgca cccgttgata tgcctcccag gacccagagg gagactgtag
361 cctcatttct gtggagacct ttggctggac tctcctggct ctcccagaga ctccagttcc
421 aacaccatct tctgagatga tcctgattcc cagaatgctc ttggtgctgt tcctgctgct
481 gcctatcttg agttctgcaa aagctcaggt taatccagct atatgccgct atcctctggg
541 catgtcagga ggccagattc cagatgagga catcacagct tccagtcagt ggtcagagtc
601 cacagctgcc aaatatggaa ggctggactc agaagaaggg gatggagcct ggtgccctga
661 gattccagtg gaacctgatg acctgaagga gtttctgcag attgacttgc acaccctcca
721 ttttatcact ctggtgggga cccaggggcg ccatgcagga ggtcatggca tcgagtttgc
781 ccccatgtac aagatcaatt acagtcggga tggcactcgc tggatctctt ggcggaaccg
841 tcatgggaaa caggtgctgg atggaaatag taacccctat gacattttcc taaaggactt
901 ggagccgccc attgtagcca gatttgtccg gttcattcca gtcaccgacc actccatgaa
961 tgtgtgtatg agagtggagc tttacggctg tgtctggcta gatggcttgg tgtcttacaa
1021 tgctccagct gggcagcagt ttgtactccc tggaggttcc atcatttatc tgaatgattc
1081 tgtctatgat ggagctgttg gatacagcat gacagaaggg ctaggccaat tgaccgatgg
1141 tgtgtctggc ctggacgatt tcacccagac ccatgaatac cacgtgtggc ccggctatga
1201 ctatgtgggc tggcggaacg agagtgccac caatggctac attgagatca tgtttgaatt
1261 tgaccgcatc aggaatttca ctaccatgaa ggtccactgc aacaacatgt ttgctaaagg
1321 tgtgaagatc tttaaggagg tacagtgcta cttccgctct gaagccagtg agtgggaacc
1381 taatgccatt tccttccccc ttgtcctgga tgacgtcaac cccagtgctc ggtttgtcac
1441 ggtgcctctc caccaccgaa tggccagtgc catcaagtgt caataccatt ttgcagatac
1501 ctggatgatg ttcagtgaga tcaccttcca atcagatgct gcaatgtaca acaactctga
1561 agccctgccc acctctccta tggcacccac aacctatgat ccaatgctta aagttgatga
1621 cagcaacact cggatcctga ttggctgctt ggtggccatc atctttatcc tcctggccat
1681 cattgtcatc atcctctgga ggcagttctg gcagaaaatg ctggagaagg cttctcggag
1741 gatgctggat gatgaaatga cagtcagcct ttccctgcca agtgattcta gcatgttcaa
1801 caataaccgc tcctcatcac ctagtgaaca agggtccaac tcgacttacg atcgcatctt
1861 tccccttcgc cctgactacc aggagccatc caggctgata cgaaaactcc cagaatttgc
1921 tccaggggag gaggagtcag gctgcagcgg tgttgtgaag ccagtccagc ccagtggccc
1981 tgagggggtg ccccactatg cagaggctga catagtgaac ctccaaggag tgacaggagg
2041 caacacatac tcagtgcctg ccgtcaccat ggacctgctc tcaggaaaag atgtggctgt
2101 ggaggagttc cccaggaaac tcctaacttt caaagagaag ctgggagaag gacagtttgg
2161 ggaggttcat ctctgtgaag tggagggaat ggaaaaattc aaagacaaag attttgccct
2221 agatgtcagt gccaaccagc ctgtcctggt ggctgtgaaa atgctccgag cagatgccaa
2281 caagaatgcc aggaatgatt ttcttaagga gataaagatc atgtctcggc tcaaggaccc
2341 aaacatcatc catctattag ctgtgtgtat cactgatgac cctctctgta tgatcactga
2401 atacatggag aatggagatc tcaatcagtt tctttcccgc cacgagcccc ctaattcttc
2461 ctccagcgat gtacgcactg tcagttacac caatctgaag tttatggcta cccaaattgc
2521 ctctggcatg aagtaccttt cctctcttaa ttttgttcac cgagatctgg ccacacgaaa
2581 ctgtttagtg ggtaagaact acacaatcaa gatagctgac tttggaatga gcaggaacct
2641 gtacagtggt gactattacc ggatccaggg ccgggcagtg ctccctatcc gctggatgtc
2701 ttgggagagt atcttgctgg gcaagttcac tacagcaagt gatgtgtggg cctttggggt
2761 tactttgtgg gagactttca ccttttgtca agaacagccc tattcccagc tgtcagatga
2821 acaggttatt gagaatactg gagagttctt ccgagaccaa gggaggcaga cttacctccc
2881 tcaaccagcc atttgtcctg actctgtgta taagctgatg ctcagctgct ggagaagaga
2941 tacgaagaac cgtccctcat tccaagaaat ccaccttctg ctccttcaac aaggcgacga
3001 gtgatgctgt cagtgcctgg ccatgttcct acggctcagg tcctccctac aagacctacc
3061 actcacccat gcctatgcca ctccatctgg acatttaatg aaactgagag acagaggctt
3121 gtttgctttg ccctcttttc ctggtcaccc ccactcccta cccctgactc atatatactt
3181 tttttttttt acattaaaga actaaaaaag gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3241 aaaaaaaaaa aaaaaaaaaa aaa
//