LOCUS BC052804 4046 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens EPH receptor B4, mRNA (cDNA clone MGC:59690
IMAGE:6584384), complete cds.
ACCESSION BC052804
VERSION BC052804.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4046)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4046)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: n Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 55774978.
FEATURES Location/Qualifiers
source 1..4046
/db_xref="H-InvDB:HIT000053828"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59690 IMAGE:6584384"
/tissue_type="Ovary, teratocarcinoma"
/clone_lib="NIH_MGC_109"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4046
/gene="EPHB4"
/gene_synonym="MYK1"
/gene_synonym="TYRO11"
/db_xref="GeneID:2050"
/db_xref="HGNC:HGNC:3395"
/db_xref="MIM:600011"
CDS 169..3132
/gene="EPHB4"
/gene_synonym="MYK1"
/gene_synonym="TYRO11"
/codon_start=1
/product="EPH receptor B4"
/protein_id="AAH52804.1"
/db_xref="GeneID:2050"
/db_xref="HGNC:HGNC:3395"
/db_xref="MIM:600011"
/translation="MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEE
LSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPR
AGRSCKETFTVFYYESDADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVN
VRTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCAQLTVNLTRFPETVPRELVVP
VAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTF
KPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRL
NGSSLHLEWSAPLESGGREDLTYALRCRECRPGGSCAPCGGDLTFDPGPRDLVEPWVV
VRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSL
SLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVR
ARSEAGYGPFGQEHHSQTQLDESEGWREQLALIAGTAVVGVVLVLVVIVVAVLCLRKQ
SNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAG
EFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGV
VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRD
LAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFT
SASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDC
WQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGE
WLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQA
KPGTPGGTGGPAPQY"
BASE COUNT 790 a 1221 c 1246 g 789 t
ORIGIN
1 cttggcgccg ccgcccggtg ccccgcacgc tcgcatgggc ccgcgctgag ggccccgacg
61 aggagtcccg cgcggagtat cggcgtccac ccgcccaggg agagtcagac ctgggggggc
121 gagggccccc caaactcagt tcggatccta cccgagtgag gcggcgccat ggagctccgg
181 gtgctgctct gctgggcttc gttggccgca gctttggaag agaccctgct gaacacaaaa
241 ttggaaactg ctgatctgaa gtgggtgaca ttccctcagg tggacgggca gtgggaggaa
301 ctgagcggcc tggatgagga acagcacagc gtgcgcacct acgaagtgtg tgacgtgcag
361 cgtgccccgg gccaggccca ctggcttcgc acaggttggg tcccacggcg gggcgccgtc
421 cacgtgtacg ccacgctgcg cttcaccatg ctcgagtgcc tgtccctgcc tcgggctggg
481 cgctcctgca aggagacctt caccgtcttc tactatgaga gcgatgcgga cacggccacg
541 gccctcacgc cagcctggat ggagaacccc tacatcaagg tggacacggt ggccgcggag
601 catctcaccc ggaagcgccc tggggccgag gccaccggga aggtgaatgt caggacgctg
661 cgtctgggac cgctcagcaa ggctggcttc tacctggcct tccaggacca gggtgcctgc
721 atggccctgc tatccctgca cctcttctac aaaaagtgcg cccagctgac tgtgaacctg
781 actcgattcc cggagactgt gcctcgggag ctggttgtgc ccgtggccgg tagctgcgtg
841 gtggatgccg tccccgcccc tggccccagc cccagcctct actgccgtga ggatggccag
901 tgggccgaac agccggtcac gggctgcagc tgtgctccgg ggttcgaggc agctgagggg
961 aacaccaagt gccgagcctg tgcccagggc accttcaagc ccctgtcagg agaagggtcc
1021 tgccagccat gcccagccaa tagccactct aacaccattg gatcagccgt ctgccagtgc
1081 cgcgtcgggt acttccgggc acgcacagac ccccggggtg caccctgcac cacccctcct
1141 tcggctccgc ggagcgtggt ttcccgcctg aacggctcct ccctgcacct ggaatggagt
1201 gcccccctgg agtctggtgg ccgagaggac ctcacctacg ccctccgctg ccgggagtgc
1261 cgacccggag gctcctgtgc gccctgcggg ggagacctga cttttgaccc cggcccccgg
1321 gacctggtgg agccctgggt ggtggttcga gggctacgtc ctgacttcac ctataccttt
1381 gaggtcactg cattgaacgg ggtatcctcc ttagccacgg ggcccgtccc atttgagcct
1441 gtcaatgtca ccactgaccg agaggtacct cctgcagtgt ccgacatccg ggtgacgcgg
1501 tcctcaccca gcagcttgag cctggcctgg gctgttcccc gggcacccag tggggctgtg
1561 ctggactacg aggtcaaata ccatgagaag ggcgccgagg gtcccagcag cgtgcggttc
1621 ctgaagacgt cagaaaaccg ggcagagctg cgggggctga agcggggagc cagctacctg
1681 gtgcaggtac gggcgcgctc tgaggccggc tacgggccct tcggccagga acatcacagc
1741 cagacccaac tggatgagag cgagggctgg cgggagcagc tggccctgat tgcgggcacg
1801 gcagtcgtgg gtgtggtcct ggtcctggtg gtcattgtgg tcgcagttct ctgcctcagg
1861 aagcagagca atgggagaga agcagaatat tcggacaaac acggacagta tctcatcggg
1921 catggtacta aggtctacat cgaccccttc acttatgaag accctaatga ggctgtgagg
1981 gaatttgcaa aagagatcga tgtctcctac gtcaagattg aagaggtgat tggtgcaggt
2041 gagtttggcg aggtgtgccg ggggcggctc aaggccccag ggaagaagga gagctgtgtg
2101 gcaatcaaga ccctgaaggg tggctacacg gagcggcagc ggcgtgagtt tctgagcgag
2161 gcctccatca tgggccagtt cgagcacccc aatatcatcc gcctggaggg cgtggtcacc
2221 aacagcatgc ccgtcatgat tctcacagag ttcatggaga acggcgccct ggactccttc
2281 ctgcggctaa acgacggaca gttcacagtc atccagctcg tgggcatgct gcggggcatc
2341 gcctcgggca tgcggtacct tgccgagatg agctacgtcc accgagacct ggctgctcgc
2401 aacatcctag tcaacagcaa cctcgtctgc aaagtgtctg actttggcct ttcccgattc
2461 ctggaggaga actcttccga tcccacctac acgagctccc tgggaggaaa gattcccatc
2521 cgatggactg ccccggaggc cattgccttc cggaagttca cttccgccag tgatgcctgg
2581 agttacggga ttgtgatgtg ggaggtgatg tcatttgggg agaggccgta ctgggacatg
2641 agcaatcagg acgtgatcaa tgccattgaa caggactacc ggctgccccc gcccccagac
2701 tgtcccacct ccctccacca gctcatgctg gactgttggc agaaagaccg gaatgcccgg
2761 ccccgcttcc cccaggtggt cagcgccctg gacaagatga tccggaaccc cgccagcctc
2821 aaaatcgtgg cccgggagaa tggcggggcc tcacaccctc tcctggacca gcggcagcct
2881 cactactcag cttttggctc tgtgggcgag tggcttcggg ccatcaaaat gggaagatac
2941 gaagaaagtt tcgcagccgc tggctttggc tccttcgagc tggtcagcca gatctctgct
3001 gaggacctgc tccgaatcgg agtcactctg gcgggacacc agaagaaaat cttggccagt
3061 gtccagcaca tgaagtccca ggccaagccg ggaaccccgg gtgggacagg aggaccggcc
3121 ccgcagtact gacctgcagg aactccccac cccagggaca ccgcctcccc attttccggg
3181 gcagagtggg gactcacaga ggcccccagc cctgtgcccc gctggattgc actttgagcc
3241 cgtggggtga ggagttggca atttggagag acaggatttg ggggttctgc cataatagga
3301 ggggaaaatc accccccagc cacctcgggg aactccagac caagggtgag ggcgcctttc
3361 cctcaggact gggtgtgacc agaggaaaag gaagtgccca acatctccca gcctccccag
3421 gtgcccccct caccttgatg ggtgcgttcc cgcagaccaa agagagtgtg actcccttgc
3481 cagctccaga gtgggggggc tgtcccaggg ggcaagaagg ggtgtcaggg cccagtgaca
3541 aaatcattgg ggtttgtagt cccaacttgc tgctgtcacc accaaactca atcatttttt
3601 tcccttgtaa atgcccctcc cccagctgct gccttcatat tgaaggtttt tgagttttgt
3661 ttttggtctt aatttttctc cccgttccct ttttgtttct tcgttttgtt tttctaccgt
3721 ccttgtcata actttgtgtt ggagggaacc tgtttcacta tggcctcctt tgcccaagtt
3781 gaaacagggg cccatcatca tgtctgtttc cagaacagtg ccttggtcat cccacatccc
3841 cggaccccgc ctgggacccc caagctgtgt cctatgaagg ggtgtggggt gaggtagtga
3901 aaagggcggt agttggtggt ggaacccaga aacggacgcc ggtgcttgga ggggttctta
3961 aattatattt aaaaaagtaa ctttttgtat aaataaaaga aaatgggacg tgtcccagct
4021 ccaggggtaa aaaaaaaaaa aaaaaa
//