LOCUS BC052605 1083 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens TIMP metallopeptidase inhibitor 2, mRNA (cDNA clone
MGC:59751 IMAGE:6267022), complete cds.
ACCESSION BC052605
VERSION BC052605.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1083)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1083)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: h Column: 6.
FEATURES Location/Qualifiers
source 1..1083
/db_xref="H-InvDB:HIT000053813"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59751 IMAGE:6267022"
/tissue_type="Skin, melanoma, melanotic"
/clone_lib="NIH_MGC_112"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1083
/gene="TIMP2"
/gene_synonym="CSC-21K"
/db_xref="GeneID:7077"
/db_xref="HGNC:HGNC:11821"
/db_xref="MIM:188825"
CDS 280..942
/gene="TIMP2"
/gene_synonym="CSC-21K"
/codon_start=1
/product="TIMP metallopeptidase inhibitor 2"
/protein_id="AAH52605.1"
/db_xref="GeneID:7077"
/db_xref="HGNC:HGNC:11821"
/db_xref="MIM:188825"
/translation="MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVV
IRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSL
DVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCP
MIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIE
DP"
BASE COUNT 244 a 373 c 317 g 149 t
ORIGIN
1 gcagcgcggc cgccgagaac cgcagcgccg ctcgcccgcc gccccccacc ccgccgcccc
61 gcccggcgaa ttgcgccccg cgcccctccc ctcgcgcccc cgagacaaag aggagagaaa
121 gtttgcgcgg ccgagcgggg caggtgagga gggtgagccg cgcgggaggg gcccgcctcg
181 gccccggctc agcccccgcc cgcgccccca gcccgccgcc gcgagcagcg cccggacccc
241 ccagcggcgg cccccgcccg cccagccccc cggcccgcca tgggcgccgc ggcccgcacc
301 ctgcggctgg cgctcggcct cctgctgctg gcgacgctgc ttcgcccggc cgacgcctgc
361 agctgctccc cggtgcaccc gcaacaggcg ttttgcaatg cagatgtagt gatcagggcc
421 aaagcggtca gtgagaagga agtggactct ggaaacgaca tttatggcaa ccctatcaag
481 aggatccagt atgagatcaa gcagataaag atgttcaaag ggcctgagaa ggatatagag
541 tttatctaca cggccccctc ctcggcagtg tgtggggtct cgctggacgt tggaggaaag
601 aaggaatatc tcattgcagg aaaggccgag ggggacggca agatgcacat caccctctgt
661 gacttcatcg tgccctggga caccctgagc accacccaga agaagagcct gaaccacagg
721 taccagatgg gctgcgagtg caagatcacg cgctgcccca tgatcccgtg ctacatctcc
781 tccccggacg agtgcctctg gatggactgg gtcacagaga agaacatcaa cgggcaccag
841 gccaagttct tcgcctgcat caagagaagt gacggctcct gtgcgtggta ccgcggcgcg
901 gcgcccccca agcaggagtt tctcgacatc gaggacccat aagcaggcct ccaacgcccc
961 tgtggccaac tgcaaaaaaa gcctccaagg gtttcgactg gtccagctct gacatccctt
1021 cctggaaaca gcatgaataa aacactcatc ccatgggaaa aaaaaaaaaa aaaaaaaaaa
1081 aaa
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