LOCUS BC052274 2689 bp mRNA linear HUM 17-JUL-2007
DEFINITION Homo sapiens POU class 2 homeobox 1, mRNA (cDNA clone MGC:59844
IMAGE:4622256), complete cds.
ACCESSION BC052274
VERSION BC052274.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2689)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2689)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: b Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42476163.
FEATURES Location/Qualifiers
source 1..2689
/db_xref="H-InvDB:HIT000053762"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59844 IMAGE:4622256"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2689
/gene="POU2F1"
/gene_synonym="OCT1"
/db_xref="GeneID:5451"
/db_xref="HGNC:HGNC:9212"
/db_xref="MIM:164175"
CDS 163..2394
/gene="POU2F1"
/gene_synonym="OCT1"
/codon_start=1
/product="POU class 2 homeobox 1"
/protein_id="AAH52274.1"
/db_xref="GeneID:5451"
/db_xref="HGNC:HGNC:9212"
/db_xref="MIM:164175"
/translation="MNNPSETSKPSMESGDGNTGTQTNGLDFQKQPVPVGGAISTAQA
QAFLGHLHQVQLAGTSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQPSVQAAIPQTQL
MLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATP
MTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGL
LQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTPKRIDT
PSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL
SFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRV
ALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPI
KAIFPSPTSLVATTPSLVTSSAATTLTVSPVLPLTSAAVTNLSVTGTSDTTSNNTATV
ISTAPPASSAVTSPSLSPSPSASASTSEASSASETSTTQTTSTPLSSPLGTSQVMVTA
SGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPSLMAPSQFAAGGALLSLNPGTLSG
ALSPALMSNSTLATIQALASGGSLPITSLDATGNLVFANAGGAPNIVTAPLFLNPQNL
SLLTSNPVSLVSAAAASAGNSAPVASLHATSTSAESIQNSLFTVASASGAASTTTTAS
KAQ"
BASE COUNT 743 a 804 c 589 g 553 t
ORIGIN
1 cggaggagca gcgagtcaag atgagagttc agccgcggcg gcagcagcag cagactggaa
61 aagtaagaag agctttcctg cctttttaat taccaaacta ctctcagttt tcaatgaatc
121 agttcaaaga aagaatgcag tctttctata cctgactcaa gaatgaacaa tccgtcagaa
181 accagtaaac catctatgga gagtggagat ggcaacacag gcacacaaac caatggtctg
241 gactttcaga agcagcctgt gcctgtagga ggagcaatct caacagccca ggcgcaggct
301 ttccttggac atctccatca ggtccaactc gctggaacaa gtttacaggc tgctgctcag
361 tctttaaatg tacagtctaa atctaatgaa gaatcggggg attcgcagca gccaagccag
421 ccttcccagc agccttcagt gcaggcagcc attccccaga cccagcttat gctagctgga
481 ggacagataa ctgggcttac tttgacgcct gcccagcaac agttactact ccagcaggca
541 caggcacagg cacagctgct ggctgctgca gtgcagcagc actccgccag ccagcagcac
601 agtgctgctg gagccaccat ctccgcctct gctgccacgc ccatgacgca gatccccctg
661 tctcagccca tacagatcgc acaggatctt caacaactgc aacagcttca acagcagaat
721 ctcaacctgc aacagtttgt gttggtgcat ccaaccacca atttgcagcc agcgcagttt
781 atcatctcac agacgcccca gggccagcag ggtctcctgc aagcgcaaaa tcttctaacg
841 caactacctc agcaaagcca agccaacctc ctacagtcgc agccaagcat caccctcacc
901 tcccagccag caaccccaac acgcacaata gcagcaaccc caattcagac acttccacag
961 agccagtcaa caccaaagcg aattgatact cccagcttgg aggagcccag tgaccttgag
1021 gagcttgagc agtttgccaa gaccttcaaa caaagacgaa tcaaacttgg attcactcag
1081 ggtgatgttg ggctcgctat ggggaaacta tatggaaatg acttcagcca aactaccatc
1141 tctcgatttg aagccttgaa cctcagcttt aagaacatgt gcaagttgaa gccactttta
1201 gagaagtggc taaatgatgc agagaacctc tcatctgatt cgtccctctc cagcccaagt
1261 gccctgaatt ctccaggaat tgagggcttg agccgtagga ggaagaaacg caccagcata
1321 gagaccaaca tccgtgtggc cttagagaag agtttcttgg agaatcaaaa gcctacctcg
1381 gaagagatca ctatgattgc tgatcagctc aatatggaaa aagaggtgat tcgtgtttgg
1441 ttctgtaacc gccgccagaa agaaaaaaga atcaacccac caagcagtgg tgggaccagc
1501 agctcaccta ttaaagcaat tttccccagc ccaacttcac tggtggcgac cacaccaagc
1561 cttgtgacta gcagtgcagc aactaccctc acagtcagcc ctgtcctccc tctgaccagt
1621 gctgctgtga cgaatctttc agttacaggc acttcagaca ccacctccaa caacacagca
1681 accgtgattt ccacagcgcc tccagcttcc tcagcagtca cgtccccctc tctgagtccc
1741 tccccttctg cctcagcctc cacctccgag gcatccagtg ccagtgagac cagcacaaca
1801 cagaccacct ccactccttt gtcctcccct cttgggacca gccaggtgat ggtgacagca
1861 tcaggtttgc aaacagcagc agctgctgcc cttcaaggag ctgcacagtt gccagcaaat
1921 gccagtcttg ctgccatggc agctgctgca ggactaaacc caagcctgat ggcaccctca
1981 cagtttgcgg ctggaggtgc cttactcagt ctgaatccag ggaccctgag cggtgctctc
2041 agcccagctc taatgagcaa cagtacactg gcaactattc aagctcttgc ttctggtggc
2101 tctcttccaa taacatcact tgatgcaact gggaacctgg tatttgccaa tgcgggagga
2161 gcccccaaca tcgtgactgc ccctctgttc ctgaaccctc agaacctctc tctgctcacc
2221 agcaaccctg ttagcttggt ctctgccgcc gcagcatctg cagggaactc tgcacctgta
2281 gccagccttc acgccacctc cacctctgct gagtccatcc agaactctct cttcacagtg
2341 gcctctgcca gcggggctgc gtccaccacc accaccgcct ccaaggcaca gtgagctggg
2401 cagagctggg ctgccagaag cctttttcac tctgcagtgt gattggactg ccagccaggt
2461 taataaactg aaaaatgtga ttggcttcct ctcgccgtgt tgtgagggca aaggagagaa
2521 gggagaaaaa aaaaaaaaaa ccacacacac ccatacacac ataccagaaa aagaaagaaa
2581 ggatggagac ggaacatttg cctaattttg taataaaaca ctgtcttttc aggattgctt
2641 catggattgg agaactttct aaccaaaaat taaaaaaaaa aaaaaaaaa
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