LOCUS BC052264 2065 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cyclin-dependent kinase 6, mRNA (cDNA clone MGC:59692
IMAGE:6377987), complete cds.
ACCESSION BC052264
VERSION BC052264.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2065)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2065)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: l Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45827787.
FEATURES Location/Qualifiers
source 1..2065
/db_xref="H-InvDB:HIT000053759"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59692 IMAGE:6377987"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_47"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2065
/gene="CDK6"
/gene_synonym="MGC59692"
/gene_synonym="PLSTIRE"
/db_xref="GeneID:1021"
/db_xref="HGNC:HGNC:1777"
/db_xref="MIM:603368"
CDS 394..1374
/gene="CDK6"
/gene_synonym="MGC59692"
/gene_synonym="PLSTIRE"
/codon_start=1
/product="cyclin-dependent kinase 6"
/protein_id="AAH52264.1"
/db_xref="GeneID:1021"
/db_xref="HGNC:HGNC:1777"
/db_xref="MIM:603368"
/translation="MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKR
VRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVD
QDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIK
LADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPL
FRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDL
LLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA"
BASE COUNT 498 a 505 c 572 g 490 t
ORIGIN
1 ggcttcagcc ctgcagggaa agaaaagtgc aatgattctg gactgagacg cgcttgggca
61 gaggctatgt aatcgtgtct gtgttgagga cttcgcttcg aggagggaag aggagggatc
121 ggctcgctcc tccggcggcg gcggcggcgg cgactctgca ggcggagttt cgcggcggcg
181 gcaccagggt tacgccagcc ccgcggggag gtctctccat ccagcttctg cagcggcgaa
241 agccccagcg cccgagcgcc tgagccggcg gggagcaagt aaagctagac cgatctccgg
301 ggagccccgg agtaggcgag cggcggccgc cagctagttg agcgcacccc ccgcccgccc
361 cagcggcgcc gcggcgggcg gcgtccaggc ggcatggaga aggacggcct gtgccgcgct
421 gaccagcagt acgaatgcgt ggcggagatc ggggagggcg cctatgggaa ggtgttcaag
481 gcccgcgact tgaagaacgg aggccgtttc gtggcgttga agcgcgtgcg ggtgcagacc
541 ggcgaggagg gcatgccgct ctccaccatc cgcgaggtgg cggtgctgag gcacctggag
601 accttcgagc accccaacgt ggtcaggttg tttgatgtgt gcacagtgtc acgaacagac
661 agagaaacca aactaacttt agtgtttgaa catgtcgatc aagacttgac cacttacttg
721 gataaagttc cagagcctgg agtgcccact gaaaccataa aggatatgat gtttcagctt
781 ctccgaggtc tggactttct tcattcacac cgagtagtgc atcgcgatct aaaaccacag
841 aacattctgg tgaccagcag cggacaaata aaactcgctg acttcggcct tgcccgcatc
901 tatagtttcc agatggctct aacctcagtg gtcgtcacgc tgtggtacag agcacccgaa
961 gtcttgctcc agtccagcta cgccaccccc gtggatctct ggagtgttgg ctgcatattt
1021 gcagaaatgt ttcgtagaaa gcctcttttt cgtggaagtt cagatgttga tcaactagga
1081 aaaatcttgg acgtgattgg actcccagga gaagaagact ggcctagaga tgttgccctt
1141 cccaggcagg cttttcattc aaaatctgcc caaccaattg agaagtttgt aacagatatc
1201 gatgaactag gcaaagacct acttctgaag tgtttgacat ttaacccagc caaaagaata
1261 tctgcctaca gtgccctgtc tcacccatac ttccaggacc tggaaaggtg caaagaaaac
1321 ctggattccc acctgccgcc cagccagaac acctcggagc tgaatacagc ctgaggcctc
1381 agcagccgcc ttaagctgat cctgcggaga acacccttgg tggcttatgg gtccccctca
1441 gcaagcccta cagagctgtg gaggattgct atctggaggc cttccagctg ctgtcttctg
1501 gacaggctct gcttctccaa ggaaaccgcc tagtttactg ttttgaaatc aatgcaagag
1561 tgattgcagc tttatgttca tttgtttgtt tgtttgtctg tttgtttcaa gaacctggaa
1621 aaattccaga agaagagaag ctgctgacca attgtgctgc catttgattt ttctaacctt
1681 gaatgctgcc agtgtggagt gggtaatcca ggcacagctg agttatgatg taatctctct
1741 gcagctgccg ggcctgattt ggtacttttg agtgtgtgtg tgcatgtgtg tgtgtgtgtg
1801 tgtgtgtgtg tgtgtgtatg tgagagattc tgtgatcttt taaagtgtta ctttttgtaa
1861 acgacaagaa taattcaatt ttaaagactc aaggtggtca gtaaataaca ggcatttgtt
1921 cactgaaggt gattcaccaa aatagtcttc tcaaattaga aagttaaccc catgtcctca
1981 gcatttcttt tctggccaaa agcagtaaat ttgctagcag taaaagatga agttttatac
2041 acacagcaaa aaaaaaaaaa aaaaa
//