LOCUS BC052252 1729 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens exosome component 6, mRNA (cDNA clone MGC:59978
IMAGE:6256140), complete cds.
ACCESSION BC052252
VERSION BC052252.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1729)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1729)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: h Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32484988.
FEATURES Location/Qualifiers
source 1..1729
/db_xref="H-InvDB:HIT000099481"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59978 IMAGE:6256140"
/tissue_type="Salivary gland, epidermoid carcinoma"
/clone_lib="NIH_MGC_102"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..1729
/gene="EXOSC6"
/gene_synonym="EAP4"
/gene_synonym="hMtr3p"
/gene_synonym="MTR3"
/gene_synonym="Mtr3p"
/gene_synonym="p11"
/db_xref="GeneID:118460"
/db_xref="HGNC:HGNC:19055"
/db_xref="MIM:606490"
CDS 31..849
/gene="EXOSC6"
/gene_synonym="EAP4"
/gene_synonym="hMtr3p"
/gene_synonym="MTR3"
/gene_synonym="Mtr3p"
/gene_synonym="p11"
/codon_start=1
/product="exosome component 6"
/protein_id="AAH52252.1"
/db_xref="GeneID:118460"
/db_xref="HGNC:HGNC:19055"
/db_xref="MIM:606490"
/translation="MPGDHRRIRGPEESQPPQLYAADEEEAPGTRDPTRLRPVYARAG
LLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRR
APFAGRRRRAPPGGCEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAA
ALTAAALALADAGVEMYDLVVGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVALMPV
LNQVAGLLGSGEGGLTESWAEAVRLGLEGCQRLYPVLQQSLVRAARRRGAAAQP"
BASE COUNT 304 a 526 c 558 g 341 t
ORIGIN
1 gcggaagggg ttcgcacgcc aagaaccgcc atgcctgggg atcaccgccg catccgcggc
61 cctgaagaat cgcagccgcc gcagctgtac gcggccgacg aggaggaggc gcccggcacc
121 cgcgacccaa cgcggctacg gcccgtgtac gcgcgcgccg ggctgctgag ccaggccaag
181 ggctcggcct acctggaggc gggaggcacc aaggtgctgt gtgccgtgtc gggcccgcga
241 caggccgagg gcggcgagcg cggcggcggc ccggccggag caggcggcga ggccccggcc
301 gcgctgcgcg gtcgcctgct ctgcgacttc cgccgcgcac ccttcgcggg ccgccggcgc
361 cgcgctcccc cgggcggctg cgaggagcgt gagctggcgc tggcgctgca ggaggcgctg
421 gagccggctg tgcgcctggg ccgctacccg cgcgcgcagc tcgaggtgtc ggcgctgctg
481 ctggaggacg gtggctcggc cctggccgcc gcgctcaccg ccgccgcgct cgccctggcc
541 gacgcgggcg tggagatgta cgacctggtg gtgggctgcg gcctcagcct cgcgccgggg
601 cccgcgccca cctggctcct ggaccccacg cggctcgagg aagagcgcgc cgccgccggc
661 ctcaccgtgg cgctcatgcc tgtgctgaat caggtggccg ggctgctggg cagcggcgag
721 ggcggcctga cagagagctg ggcggaggcc gtacgcctgg gcctcgaggg ctgccagcgc
781 ctctaccccg tgctgcagca gagcctggtg cgggccgccc gccgcagggg cgccgccgcc
841 cagccctgaa ccagaagcct gagcaactac ggacgcaagc cgaggaccgt gctgccgccg
901 tccacgaaaa gacccgcgcc atcggcctcc agtttgcgtc gagaattcct ggaagggccc
961 tgatatgact gtggttggac tgacctgact gccagatggt gggacttggt ctggagcagg
1021 gactacttgg aatgataaag gcaaaactca acagcccctg gagctgcgct tgtggtggag
1081 ctggaccctg aaattacctg gacctttttt ttagagacag ggtttctttc tgcagtctca
1141 aactcctagc cttgattgat cctcctgcct tggcctccca aagtgctggg actacaggtg
1201 catgcaacca cacctggcta attttctttt cttctttctt tctttttttt tttttttttt
1261 ttttgatgga gtcttgttct gttgcccagg ctggagtgca atggtgcaat cttggctcac
1321 tgcaacctct gcctcctggg ttcaatccat tctcctgcct cagcctccca agtagctggg
1381 attacaggca catgcctcca taccgggcta atttttgtat ttttagtaga gatggggttt
1441 cgccatgtgg gccaggctgt tctcgaatgc ctgacctcag gtgatccacc cgccttggcc
1501 tcccaaagtg ctggaattac aggtgtgagc cactgtgccc agctgagtaa atttcttgat
1561 tgcacagaat gtacggtgat attggcggac ttaaggacat cgaattgttt atcaggaata
1621 aagtattatg tgtgttttct gcggccctgg ataatgctgt agcattcagg gtcgattgag
1681 taaaaaaaat gtagagatgg aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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