LOCUS BC051913 3096 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens sex comb on midleg-like 2 (Drosophila), mRNA (cDNA
clone IMAGE:6526919), partial cds.
ACCESSION BC051913
VERSION BC051913.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3096)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3096)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: p Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 5174668.
FEATURES Location/Qualifiers
source 1..3096
/db_xref="H-InvDB:HIT000099464"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6526919"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..3096
/gene="SCML2"
/db_xref="GeneID:10389"
/db_xref="MIM:300208"
CDS <1..2202
/gene="SCML2"
/codon_start=1
/product="SCML2 protein"
/protein_id="AAH51913.1"
/db_xref="GeneID:10389"
/db_xref="MIM:300208"
/translation="GGVKLGAGSRDRWDRISLFSPTRLEETTPNRDTMGQTVNEDSMD
VKKENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKL
EARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDL
LQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEAIDKKN
PYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPPGTS
VPIVKNIAKTESSPSEASQHSMQSPQKTTLILPTQQVRRSSRIKPPGPTAVPKRSSSV
KNITPRKKGPNSGKKEKPLPVICSTSAASLKSLTRDRGMLYKDVASGPCKIVMSTVCV
YVNKHGNFGPHLDPKRIQQLPDHFGPGPVNVVLRRIVQACVDCALETKTVFGYLKPDN
RGGEVITASFDGETHSIQLPPVNSASFALRFLENFCHSLQCDNLLSSQPFSSSRGHTH
SSAEHDKNQSAKEDVTERQSTKRSPQQTVPYVVPLSPKLPKTKEYASEGEPLFAGGSA
IPKEENLSEDSKSSSLNSGNYLNPACRNPMYIHTSVSQDFSRSVPGTTSSPLVGDISP
KSSPHEVKFQMQRKSEAPSYIAVPDPSVLKQGFSKDPSTWSVDEVIQFMKHTDPQISG
PLADLFRQHEIDGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLKEGKYS"
misc_feature 514..819
/gene="SCML2"
/note="MBT; Region: Present in Drosophila Scm, l(3)mbt,
and vertebrate SCML2"
/db_xref="CDD:smart00561"
misc_feature 1984..2184
/gene="SCML2"
/note="SAM; Region: SAM domain (Sterile alpha motif). It
has been suggested that SAM is an evolutionarily conserved
protein binding domain that is involved in the regulation
of numerous developmental processes in diverse eukaryotes.
The SAM domain can potentially function as a protein
interaction module through its ability to homo- and
heterooligomerise with other SAM domains"
/db_xref="CDD:pfam00536"
BASE COUNT 923 a 657 c 661 g 855 t
ORIGIN
1 ggcggtgtga agctcggtgc cggctcgcgc gatcggtggg acagaatttc gttgttttca
61 ccgacgagac tggaggaaac aacaccaaat agggatacca tgggacaaac agtgaatgaa
121 gattccatgg atgtcaagaa ggagaatcaa gagaaaactc ctcagtcaag tacatcttct
181 gtacaaaggg atgatttcca ctgggaggag tatttgaaag agactgggtc tataagtgct
241 ccttcagagt gcttccgtca gtctcagatt ccacctgtga atgatttcaa agttggtatg
301 aaattggaag cccgtgaccc tcgcaatgcc acttcagtat gtattgctac ggttattgga
361 attactgggg ccaggttacg gttacgactg gatggtagtg acaacagaaa tgatttttgg
421 aggcttgtcg attccccaga catacaacct gttgggacat gtgaaaagga aggagactta
481 cttcaacctc cactagggta ccagatgaat acatcctcct ggccgatgtt cctcttaaag
541 acactaaatg ggtctgaaat ggcatctgcc acattattta agaaggaacc accaaagccc
601 ccactaaata attttaaagt ggggatgaaa ctggaagcta ttgacaaaaa gaacccgtat
661 ctcatctgtc ctgcgaccat tggagatgtt aaaggggatg aagttcatat cacatttgat
721 ggctggagtg gagcttttga ttactggtgc aagtatgatt ctcgagatat tttcccagct
781 gggtggtgtc gcctgacagg agatgtatta caacccccag gaactagtgt tcctattgta
841 aagaatatag caaaaacaga gtcttctcct tccgaagcaa gccagcattc aatgcagtct
901 ccacagaaaa ctactctaat attaccaaca cagcaggtca ggagatcaag tcgaattaaa
961 ccacctggac ctactgcagt ccccaaaagg agcagttctg ttaaaaatat cacaccaagg
1021 aaaaaaggtc caaactcagg aaaaaaggaa aaacctttgc ccgtgatatg ttctacatct
1081 gcagcttctc taaaatcgct gaccagagac cgtggcatgt tatataaaga tgtcgcttct
1141 gggccatgta aaatagtgat gtctacagtc tgtgtctatg taaacaaaca tggaaacttt
1201 ggccctcatc tggatcccaa gagaatccag cagctgcctg accacttcgg cccgggcccg
1261 gtgaatgtgg tgcttcgccg gattgtgcag gcctgtgtgg attgtgccct tgaaactaaa
1321 actgtttttg gatacctgaa gccagataat cgtggaggag aagtgataac tgcctccttt
1381 gatggggaaa ctcattccat ccagctccct ccagtgaaca gtgcatcatt tgctcttcgc
1441 tttcttgaga acttctgcca cagtctgcag tgtgataacc ttttgagtag ccagcctttt
1501 agttcttcca ggggtcatac tcacagctct gcagagcatg ataaaaatca gtcagcaaaa
1561 gaagatgtaa cagaaaggca aagcaccaaa cgatctcctc agcaaactgt accatatgtt
1621 gttcctctct ctcctaagct ccccaaaaca aaggagtatg cgtctgaagg agaaccattg
1681 tttgctgggg gaagtgccat tcccaaagag gagaatcttt cagaagattc taagagctca
1741 tcactaaatt caggaaatta tttgaatcct gcctgtagaa atcctatgta tattcatact
1801 tcagtctccc aggatttttc tcgaagtgtg ccaggcacca caagttcacc actagttggg
1861 gacatatccc ccaagagcag tccccatgaa gttaaattcc aaatgcagag gaaaagtgaa
1921 gctccaagtt atatagctgt acctgatccc agtgtcctga aacaaggctt ctctaaggac
1981 ccttcaacct ggtctgtgga tgaagtgata cagtttatga aacatacaga tcctcagata
2041 tcaggccccc tcgccgacct cttcaggcaa catgaaattg atgggaaggc tctgttccta
2101 ctcaagagtg atgtgatgat gaagtatatg gggctgaagc tggggccagc attaaagctg
2161 tgttactaca ttgaaaagct taaagaagga aaatacagtt aaaaaaatgt gtaagtttag
2221 attggacata attctcaggt gtactgttaa cattttaatt taaaagtatt tctcttagca
2281 gtttttgttt tgtagacagt tcccataaaa atattttatc agaattgcag aactgtagta
2341 acagttcagt caactttgtt tttttcctgg agtcaccaac cagctttggg agacacagcc
2401 gccactcccc cagtctactt ctttaaaaag catttaacag gctggagtgc aatagctcga
2461 tctcggctca ctgcaacctc gcctccctgg ttcaagcaat tctcctgcct cagcgattac
2521 aggaatgcac caccacgccc agctaatttt gtagagatgg ggtttctcca tgttggtcag
2581 gctggtctca aactcctgac ctcaggtgat ccgcccacct cggccttgca aaatgctggg
2641 attacaggca tgagccacca tgcccagcca tgtttggggc tttattttat aagttagaac
2701 tttgaagagg aaatggtgct atatgtttat tgttattact ttgtgtaact ttgatgtaat
2761 gtttataagc tatgagaatc agttataaaa gtattagcca tttgttgtaa atgccaataa
2821 aatattcacc aggggcaaga atgtacattt tctttttaga aaaccaaatg tactttagac
2881 atgaatgcaa ctatttaaag aatagcttca tttatgttat tccttacatg tcataagatt
2941 cttacttaaa cttggtcttc tttcaagttg tttgtatgaa gatgctgtac ccacttgaac
3001 agtcctcagg tgtttacata aatactatgt tttacagttt tcatatttta aaatattaat
3061 aaagttaatc gcaacgattc aaaaaaaaaa aaaaaa
//