LOCUS BC051839 3195 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens transmembrane protease, serine 2, mRNA (cDNA clone
MGC:60144 IMAGE:6199625), complete cds.
ACCESSION BC051839
VERSION BC051839.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3195)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3195)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: o Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14602458.
FEATURES Location/Qualifiers
source 1..3195
/db_xref="H-InvDB:HIT000053702"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60144 IMAGE:6199625"
/tissue_type="Peripheral Nervous System, sympathetic
trunk"
/clone_lib="Lupski_sympathetic_trunk"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3195
/gene="TMPRSS2"
/gene_synonym="PRSS10"
/db_xref="GeneID:7113"
/db_xref="HGNC:HGNC:11876"
/db_xref="MIM:602060"
CDS 106..1584
/gene="TMPRSS2"
/gene_synonym="PRSS10"
/codon_start=1
/product="transmembrane protease, serine 2"
/protein_id="AAH51839.1"
/db_xref="GeneID:7113"
/db_xref="HGNC:HGNC:11876"
/db_xref="MIM:602060"
/translation="MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQY
YPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAA
GLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQV
YSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGN
VDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQ
NVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISH
PNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGK
TSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKN
NIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG"
BASE COUNT 765 a 803 c 849 g 778 t
ORIGIN
1 ggcggaggcg gagggcgagg ggcggggagc gccgcctgga gcgcggcagg tcatattgaa
61 cattccagat acctatcatt actcgatgct gttgataaca gcaagatggc tttgaactca
121 gggtcaccac cagctattgg accttactat gaaaaccatg gataccaacc ggaaaacccc
181 tatcccgcac agcccactgt ggtccccact gtctacgagg tgcatccggc tcagtactac
241 ccgtcccccg tgccccagta cgccccgagg gtcctgacgc aggcttccaa ccccgtcgtc
301 tgcacgcagc ccaaatcccc atccgggaca gtgtgcacct caaagactaa gaaagcactg
361 tgcatcacct tgaccctggg gaccttcctc gtgggagctg cgctggccgc tggcctactc
421 tggaagttca tgggcagcaa gtgctccaac tctgggatag agtgcgactc ctcaggtacc
481 tgcatcaacc cctctaactg gtgtgatggc gtgtcacact gccccggcgg ggaggacgag
541 aatcggtgtg ttcgcctcta cggaccaaac ttcatccttc aggtgtactc atctcagagg
601 aagtcctggc accctgtgtg ccaagacgac tggaacgaga actacgggcg ggcggcctgc
661 agggacatgg gctataagaa taatttttac tctagccaag gaatagtgga tgacagcgga
721 tccaccagct ttatgaaact gaacacaagt gccggcaatg tcgatatcta taaaaaactg
781 taccacagtg atgcctgttc ttcaaaagca gtggtttctt tacgctgtat agcctgcggg
841 gtcaacttga actcaagccg ccagagcagg atcgtgggcg gcgagagcgc gctcccgggg
901 gcctggccct ggcaggtcag cctgcacgtc cagaacgtcc acgtgtgcgg aggctccatc
961 atcacccccg agtggatcgt gacagccgcc cactgcgtgg aaaaacctct taacaatcca
1021 tggcattgga cggcatttgc ggggattttg agacaatctt tcatgttcta tggagccgga
1081 taccaagtag aaaaagtgat ttctcatcca aattatgact ccaagaccaa gaacaatgac
1141 attgcgctga tgaagctgca gaagcctctg actttcaacg acctagtgaa accagtgtgt
1201 ctgcccaacc caggcatgat gctgcagcca gaacagctct gctggatttc cgggtggggg
1261 gccaccgagg agaaagggaa gacctcagaa gtgctgaacg ctgccaaggt gcttctcatt
1321 gagacacaga gatgcaacag cagatatgtc tatgacaacc tgatcacacc agccatgatc
1381 tgtgccggct tcctgcaggg gaacgtcgat tcttgccagg gtgacagtgg agggcctctg
1441 gtcacttcga agaacaatat ctggtggctg ataggggata caagctgggg ttctggctgt
1501 gccaaagctt acagaccagg agtgtacggg aatgtgatgg tattcacgga ctggatttat
1561 cgacaaatga gggcagacgg ctaatccaca tggtcttcgt ccttgacgtc gttttacaag
1621 aaaacaatgg ggctggtttt gcttccccgt gcatgattta ctcttagaga tgattcagag
1681 gtcacttcat ttttattaaa cagtgaactt gtctggcttt ggcactctct gccattctgt
1741 gcaggctgca gtggctcccc tgcccagcct gctctcccta accccttgtc cgcaaggggt
1801 gatggccggc tggttgtggg cactggcggt caagtgtgga ggagaggggt ggaggctgcc
1861 ccattgagat cttcctgctg agtcctttcc aggggccaat tttggatgag catggagctg
1921 tcacctctca gctgctggat gacttgagat gaaaaaggag agacatggaa agggagacag
1981 ccaggtggca cctgcagcgg ctgccctctg gggccacttg gtagtgtccc cagcctacct
2041 ctccacaagg ggattttgct gatgggttct tagagcctta gcagccctgg atggtggcca
2101 gaaataaagg gaccagccct tcatgggtgg tgacgtggta gtcacttgta aggggaacag
2161 aaacattttt gttcttatgg ggtgagaata tagacagtgc ccttggtgcg agggaagcaa
2221 ttgaaaagga acttgccctg agcactcctg gtgcaggtct ccacctgcac attgggtggg
2281 gctcctggga gggagactca gccttcctcc tcatcctccc tgaccctgct cctagcaccc
2341 tggagagtgc acatgcccct tggtcctggc agggcgccaa gtctggcacc atgttggcct
2401 cttcaggcct gctagtcact ggaaattgag gtccatgggg gaaatcaagg atgctcagtt
2461 taaggtacac tgtttccatg ttatgtttct acacattgct acctcagtgc tcctggaaac
2521 ttagcttttg atgtctccaa gtagtccacc ttcatttaac tctttgaaac tgtatcatct
2581 ttgccaagta agagtggtgg cctatttcag ctgctttgac aaaatgactg gctcctgact
2641 taacgttcta taaatgaatg tgctgaagca aagtgcccat ggtggcggcg aagaagagaa
2701 agatgtgttt tgttttggac tctctgtggt cccttccaat gctgtgggtt tccaaccagg
2761 ggaagggtcc cttttgcatt gccaagtgcc ataaccatga gcactactct accatggttc
2821 tgcctcctgg ccaagcaggc tggtttgcaa gaatgaaatg aatgattcta cagctaggac
2881 ttaaccttga aatggaaagt cttgcaatcc catttgcagg atccgtctgt gcacatgcct
2941 ctgtagagag cagcattccc agggaccttg gaaacagttg gcactgtaag gtgcttgctc
3001 cccaagacac atcctaaaag gtgttgtaat ggtgaaaacg tcttccttct ttattgcccc
3061 ttcttattta tgtgaacaac tgtttgtctt tttttgtatc ttttttaaac tgtaaagttc
3121 aattgtgaaa atgaatatca tgcaaataaa ttatgcgatt tttttttcaa agtaaaaaaa
3181 aaaaaaaaaa aaaaa
//