LOCUS BC051833 2576 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens adaptor-related protein complex 1, gamma 2 subunit,
mRNA (cDNA clone MGC:60125 IMAGE:5589077), complete cds.
ACCESSION BC051833
VERSION BC051833.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2576)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2576)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Invitrogen
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: f Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18104994.
FEATURES Location/Qualifiers
source 1..2576
/db_xref="H-InvDB:HIT000053699"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60125 IMAGE:5589077"
/tissue_type="Ovary, pooled from 3 adults"
/clone_lib="NIH_MGC_125"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2576
/gene="AP1G2"
/gene_synonym="G2AD"
/db_xref="GeneID:8906"
/db_xref="MIM:603534"
CDS 376..2298
/gene="AP1G2"
/gene_synonym="G2AD"
/codon_start=1
/product="AP1G2 protein"
/protein_id="AAH51833.1"
/db_xref="GeneID:8906"
/db_xref="MIM:603534"
/translation="MDRRIENRMGTPAHRRRVVHTHRHTRNRLSCPWPPPFTSPTLTP
GILLGTITLITELCERSPAALRHFRKVVPQLVHILRTLVTMGYSTEHSISGVSDPFLQ
VQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAG
LRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASLS
RRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPTKRWHID
TILHVLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNALAEDISQQPLVQVAAW
CIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTALMKLSTR
LCGDNNRIRQVVSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVERDGPQA
DEEAKESKEAAQLSEAAPVPTEPQASQLLDLLDLLDGASGDVQHPPHLDPSPGGALVH
LLDLPCVPPPPAPIPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHF
ICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQS
VQEIFEVNNLPVESWQ"
misc_feature 541..1665
/gene="AP1G2"
/gene_synonym="G2AD"
/note="Adaptin_N; Region: Adaptin N terminal region. This
family consists of the N terminal region of various alpha,
beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor
protein complexes. The adaptor protein (AP) complexes are
involved in the formation of clathrin-coated pits and
vesicles. The N-terminal region of the various adaptor
proteins (APs) is constant by comparison to the C-terminal
which is variable within members of the AP-2 family"
/db_xref="CDD:pfam01602"
misc_feature 1951..2280
/gene="AP1G2"
/gene_synonym="G2AD"
/note="Alpha_adaptinC2; Region: pfam02883,
Alpha_adaptinC2, Adaptin C-terminal domain. Alpha adaptin
is a heterotetramer which regulates clathrin-bud
formation. The carboxyl-terminal appendage of the alpha
subunit regulates translocation of endocytic accessory
proteins to the bud site. This ig-fold domain is found in
alpha, beta and gamma adaptins"
/db_xref="CDD:pfam02883"
BASE COUNT 652 a 769 c 660 g 495 t
ORIGIN
1 cccacttcgg gaaagtcagg atggtggtgc cttcgctgaa gcttcaggac ctcatcgaag
61 agattcgcgg ggccaagact caggcccagg agcgggagtg acctgagcca ggggattcag
121 ccagtacaag gcctggcctt gtgcactttg agcaccatgg gctctgctga gatgtgccga
181 gacctggccc cagaggtgga gaaactgctc ctgcagccca gtccctacgt gcgcaagaag
241 gctattctga ctgcagtgca catgatccgg aaggtccctg aactctccag tgtcttcctc
301 ccaccctgtg cccaactgct tcatgagcgt caccatggta aggctgtggg gccccccatc
361 ctttgcttca ggtctatgga cagaagaatt gaaaatcgga tgggaacccc agctcacagg
421 agaagggtag tgcacacaca caggcacaca cgcaatagac tctcttgccc ctggccccca
481 ccattcactt ccccgacgct gaccccaggc atcctgctgg gcaccatcac gctgatcacg
541 gagctctgcg aacgaagccc tgcagccctc aggcacttcc gaaaggtggt accccagctg
601 gtacacatcc tccggactct ggtgacaatg ggatactcca cagaacacag catatctgga
661 gtcagcgacc ccttcctgca ggtccagata cttcgtctgc ttcggatcct gggccggaac
721 cacgaggaga gcagtgagac catgaatgac ttgctggccc aggtggccac taacacggac
781 accagccgaa atgccggaaa tgcggtcctg tttgagacag tactcaccat catggatatc
841 cgctctgcag ctggcctacg ggttctagct gtcaacattc ttggtcgctt cctactcaac
901 agtgacagga acattaggta tgtagccctg acatcactgc ttcgactggt gcagtctgat
961 cacagtgctg tgcagcggca tcggcccact gtggtggaat gtctacggga aactgatgcc
1021 tccctcagcc ggagagccct ggaactaagc ctggctctgg taaatagctc caatgtgcga
1081 gccatgatgc aagagctgca ggcctttctg gagtcctgcc ctcctgacct acgggctgac
1141 tgtgcctcag gcatcctgct ggctgcagag aggtttgctc caaccaaacg ctggcacata
1201 gacaccatcc tgcatgtgct gacaacggcg ggcacccatg tgcgggatga tgcagtggcc
1261 aacctgaccc agctgattgg gggggcccag gagctacatg cctactctgt gcgccgcctc
1321 tacaatgccc tggcagaaga catttcccag caaccactgg tgcaggtggc agcctggtgc
1381 attggggagt atggggacct cctgctggca gggaactgcg aggagattga gccccttcag
1441 gtggacgaag aggaagtgct ggcattgctg gaaaaggtgc tgcagtccca catgtccctg
1501 ccagccactc gaggatatgc cctcacagcc ctcatgaagc tcagcactcg cctctgtggg
1561 gacaacaacc gcatccgcca ggtggtgtcc atctacggga gctgcttgga cgtggagctg
1621 cagcagcggg ctgtggagta tgacacactc ttccggaaat acgaccacat gagggctgcc
1681 atcctggaaa aaatgcctct tgtggagcga gatggccctc aggctgatga ggaagcaaag
1741 gaaagcaaag aagcagccca gctttcagaa gcagccccag tgcccacaga gccccaggcc
1801 tcacagctcc tggatctgct agatctcctg gatggggctt ctggggatgt ccagcatcct
1861 ccccatctgg acccctcccc aggaggtgcc ctggtacacc tgcttgacct tccctgtgta
1921 cctccacccc cagctcccat cccagatctc aaagtgtttg agcgtgaggg agtacagctg
1981 aatctgtctt tcattcgacc ccctgaaaac cctgctttgc tgttaatcac catcactgcc
2041 accaacttct cagagggtga tgtcacccat ttcatctgcc aggctgctgt gcccaagagt
2101 ctccagctgc agctgcaggc ccccagtggg aacacagttc cagctcgggg tggccttcct
2161 atcacccagc tcttcagaat cctcaatcct aacaaggccc ccctgcggct aaagctgcgc
2221 ctcacctacg accactttca ccagtcggtg caggagatct ttgaggtgaa caacttgcct
2281 gtggaatcgt ggcagtaact gtctccactc acagcctgaa attctcctgt gtcccaaacc
2341 ccagggggcc ccagcagctt cgaacctaca cctgagggct accagcaggt ggcgctctgg
2401 ctttgcactg caaaaactgg ggaccagccc ccttctccca caaataaagc ccaataaagc
2461 ctgagaagtg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2521 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//