LOCUS BC051305 2780 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens transient receptor potential cation channel, subfamily
V, member 2, mRNA (cDNA clone MGC:59919 IMAGE:4870010), complete
cds.
ACCESSION BC051305
VERSION BC051305.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2780)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2780)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: c Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22547178.
FEATURES Location/Qualifiers
source 1..2780
/db_xref="H-InvDB:HIT000053616"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59919 IMAGE:4870010"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2780
/gene="TRPV2"
/gene_synonym="MGC12549"
/gene_synonym="VRL"
/gene_synonym="VRL-1"
/gene_synonym="VRL1"
/db_xref="GeneID:51393"
/db_xref="HGNC:HGNC:18082"
/db_xref="MIM:606676"
CDS 356..2650
/gene="TRPV2"
/gene_synonym="MGC12549"
/gene_synonym="VRL"
/gene_synonym="VRL-1"
/gene_synonym="VRL1"
/codon_start=1
/product="transient receptor potential cation channel,
subfamily V, member 2"
/protein_id="AAH51305.1"
/db_xref="GeneID:51393"
/db_xref="HGNC:HGNC:18082"
/db_xref="MIM:606676"
/translation="MTSPSSSPVFRLETLDGGQEDGSEADRGKLDFGSGLPPMESQFQ
GEDRKFAPQIRVNLNYRKGTGASQPDPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTS
KYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDY
YRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAAC
TKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQA
GARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSGLSHLSRKFTEWCYG
PVRVSLYDLASVDSCEENSVLEIIAFHCKSPHRHRMVVLEPLNKLLQAKWDLLIPKFF
LNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAEVGNSMLLTGHILILLGGIYLLVGQ
LWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYLPLLVSALVLGWL
NLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLFGFAVALVSLSQEAWRPEAP
TGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHFRGMVLL
LLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRKKQ
RAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLPTLCEDPSGAGVPRTLENPVLA
SPPKEDEDGASEENYVPVQLLQSN"
BASE COUNT 577 a 823 c 795 g 585 t
ORIGIN
1 gcctgtcctg acaggggaga gttaagctcc cgttctccac cgtgccggct ggccaggtgg
61 gctgagggtg accgagagac cagaacctgc ttgctggagc ttagtgctca gagctgggga
121 gggaggttcc gccgctcctc tgctgtcagc gccggcagcc cctcccggct tcacttcctc
181 ccgcagcccc tgctactgag aagctccggg atcccagcag ccgccacgcc ctggcctcag
241 cctgcggggc tccagtcagg ccaacaccga cgcgcagctg ggaggaagac aggacctttg
301 acatctccat ctgcacagag gtcctggctg gaccgagcag cctcctcctc ctaggatgac
361 ctcaccctcc agctctccag ttttcaggtt ggagacatta gatggaggcc aagaagatgg
421 ctctgaggcg gacagaggaa agctggattt tgggagcggg ctgcctccca tggagtcaca
481 gttccagggc gaggaccgga aattcgcccc tcagataaga gtcaacctca actaccgaaa
541 gggaacaggt gccagtcagc cggatccaaa ccgatttgac cgagatcggc tcttcaatgc
601 ggtctcccgg ggtgtccccg aggatctggc tggacttcca gagtacctga gcaagaccag
661 caagtacctc accgactcgg aatacacaga gggctccaca ggtaagacgt gcctgatgaa
721 ggctgtgctg aaccttaagg acggagtcaa tgcctgcatt ctgccactgc tgcagatcga
781 cagggactct ggcaatcctc agcccctggt aaatgcccag tgcacagatg actattaccg
841 aggccacagc gctctgcaca tcgccattga gaagaggagt ctgcagtgtg tgaagctcct
901 ggtggagaat ggggccaatg tgcatgcccg ggcctgcggc cgcttcttcc agaagggcca
961 agggacttgc ttttatttcg gtgagctacc cctctctttg gccgcttgca ccaagcagtg
1021 ggatgtggta agctacctcc tggagaaccc acaccagccc gccagcctgc aggccactga
1081 ctcccagggc aacacagtcc tgcatgccct agtgatgatc tcggacaact cagctgagaa
1141 cattgcactg gtgaccagca tgtatgatgg gctcctccaa gctggggccc gcctctgccc
1201 taccgtgcag cttgaggaca tccgcaacct gcaggatctc acgcctctga agctggccgc
1261 caaggagggc aagatcgaga ttttcaggca catcctgcag cgggagtttt caggactgag
1321 ccacctttcc cgaaagttca ccgagtggtg ctatgggcct gtccgggtgt cgctgtatga
1381 cctggcttct gtggacagct gtgaggagaa ctcagtgctg gagatcattg cctttcattg
1441 caagagcccg caccgacacc gaatggtcgt tttggagccc ctgaacaaac tgctgcaggc
1501 gaaatgggat ctgctcatcc ccaagttctt cttaaacttc ctgtgtaatc tgatctacat
1561 gttcatcttc accgctgttg cctaccatca gcctaccctg aagaagcagg ccgcccctca
1621 cctgaaagcg gaggttggaa actccatgct gctgacgggc cacatcctta tcctgctagg
1681 ggggatctac ctcctcgtgg gccagctgtg gtacttctgg cggcgccacg tgttcatctg
1741 gatctcgttc atagacagct actttgaaat cctcttcctg ttccaggccc tgctcacagt
1801 ggtgtcccag gtgctgtgtt tcctggccat cgagtggtac ctgcccctgc ttgtgtctgc
1861 gctggtgctg ggctggctga acctgcttta ctatacacgt ggcttccagc acacaggcat
1921 ctacagtgtc atgatccaga aggtcatcct gcgggacctg ctgcgcttcc ttctgatcta
1981 cttagtcttc cttttcggct tcgctgtagc cctggtgagc ctgagccagg aggcttggcg
2041 ccccgaagct cctacaggcc ccaatgccac agagtcagtg cagcccatgg agggacagga
2101 ggacgagggc aacggggccc agtacagggg tatcctggaa gcctccttgg agctcttcaa
2161 attcaccatc ggcatgggcg agctggcctt ccaggagcag ctgcacttcc gcggcatggt
2221 gctgctgctg ctgctggcct acgtgctgct cacctacatc ctgctgctca acatgctcat
2281 cgccctcatg agcgagaccg tcaacagtgt cgccactgac agctggagca tctggaagct
2341 gcagaaagcc atctctgtcc tggagatgga gaatggctat tggtggtgca ggaagaagca
2401 gcgggcaggt gtgatgctga ccgttggcac taagccagat ggcagccccg atgagcgctg
2461 gtgcttcagg gtggaggagg tgaactgggc ttcatgggag cagacgctgc ctacgctgtg
2521 tgaggacccg tcaggggcag gtgtccctcg aactctcgag aaccctgtcc tggcttcccc
2581 tcccaaggag gatgaggatg gtgcctctga ggaaaactat gtgcccgtcc agctcctcca
2641 gtccaactga tggcccagat gcagcaggag gccagaggac agagcagagg atctttccaa
2701 ccacatctgc tggctctggg gtcccagtga attctggtgg caaatatata ttttcactaa
2761 ctaaaaaaaa aaaaaaaaaa
//