LOCUS BC051281 3780 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens CD163 molecule, mRNA (cDNA clone MGC:59680
IMAGE:6280265), complete cds.
ACCESSION BC051281
VERSION BC051281.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3780)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3780)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Mark Watson
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: i Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 44662833.
FEATURES Location/Qualifiers
source 1..3780
/db_xref="H-InvDB:HIT000053601"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59680 IMAGE:6280265"
/tissue_type="Spleen"
/clone_lib="NIH_MGC_113"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3780
/gene="CD163"
/gene_synonym="M130"
/gene_synonym="MM130"
/db_xref="GeneID:9332"
/db_xref="HGNC:HGNC:1631"
/db_xref="MIM:605545"
CDS 61..3531
/gene="CD163"
/gene_synonym="M130"
/gene_synonym="MM130"
/codon_start=1
/product="CD163 molecule"
/protein_id="AAH51281.1"
/db_xref="GeneID:9332"
/db_xref="HGNC:HGNC:1631"
/db_xref="MIM:605545"
/translation="MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSL
GGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPG
WANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMR
LTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGS
GPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECS
GRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVS
CQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQR
LLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLW
DCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFS
LEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGT
CSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQL
KCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVIC
SGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSW
GTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQC
HSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMS
ETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRL
ASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGC
GPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTD
ISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSSRGE
NLVHQIQYREMNSCLNADDLDLMNSSENSHESADFSAAELISVSKFLPISGMEKEAIL
SHTEKENGNL"
BASE COUNT 1017 a 743 c 1070 g 950 t
ORIGIN
1 aacatttcta gggaataata caagaagatt taggaatcat tgaagttata aatctttgga
61 atgagcaaac tcagaatggt gctacttgaa gactctggat ctgctgactt cagaagacat
121 tttgtcaact tgagtccctt caccattact gtggtcttac ttctcagtgc ctgttttgtc
181 accagttctc ttggaggaac agacaaggag ctgaggctag tggatggtga aaacaagtgt
241 agcgggagag tggaagtgaa agtccaggag gagtggggaa cggtgtgtaa taatggctgg
301 agcatggaag cggtctctgt gatttgtaac cagctgggat gtccaactgc tatcaaagcc
361 cctggatggg ctaattccag tgcaggttct ggacgcattt ggatggatca tgtttcttgt
421 cgtgggaatg agtcagctct ttgggattgc aaacatgatg gatggggaaa gcatagtaac
481 tgtactcacc aacaagatgc tggagtgacc tgctcagatg gatccaattt ggaaatgagg
541 ctgacgcgtg gagggaatat gtgttctgga agaatagaga tcaaattcca aggacggtgg
601 ggaacagtgt gtgatgataa cttcaacata gatcatgcat ctgtcatttg tagacaactt
661 gaatgtggaa gtgctgtcag tttctctggt tcatctaatt ttggagaagg ctctggacca
721 atctggtttg atgatcttat atgcaacgga aatgagtcag ctctctggaa ctgcaaacat
781 caaggatggg gaaagcataa ctgtgatcat gctgaggatg ctggagtgat ttgctcaaag
841 ggagcagatc tgagcctgag actggtagat ggagtcactg aatgttcagg aagattagaa
901 gtgagattcc aaggagaatg ggggacaata tgtgatgacg gctgggacag ttacgatgct
961 gctgtggcat gcaagcaact gggatgtcca actgccgtca cagccattgg tcgagttaac
1021 gccagtaagg gatttggaca catctggctt gacagcgttt cttgccaggg acatgaacct
1081 gctgtctggc aatgtaaaca ccatgaatgg ggaaagcatt attgcaatca caatgaagat
1141 gctggcgtga catgttctga tggatcagat ctggagctaa gacttagagg tggaggcagc
1201 cgctgtgctg ggacagttga ggtggagatt cagagactgt tagggaaggt gtgtgacaga
1261 ggctggggac tgaaagaagc tgatgtggtt tgcaggcagc tgggatgtgg atctgcactc
1321 aaaacatctt atcaagtgta ctccaaaatc caggcaacaa acacatggct gtttctaagt
1381 agctgtaacg gaaatgaaac ttctctttgg gactgcaaga actggcaatg gggtggactt
1441 acctgtgatc actatgaaga agccaaaatt acctgctcag cccacaggga acccagactg
1501 gttggagggg acattccctg ttctggacgt gttgaagtga agcatggtga cacgtggggc
1561 tccatctgtg attcggactt ctctctggaa gctgccagcg ttctatgcag ggaattacag
1621 tgtggcacag ttgtctctat cctgggggga gctcactttg gagagggaaa tggacagatc
1681 tgggctgaag aattccagtg tgagggacat gagtcccatc tttcactctg cccagtagca
1741 ccccgcccag aaggaacttg tagccacagc agggatgttg gagtagtctg ctcaagatac
1801 acagaaattc gcttggtgaa tggcaagacc ccgtgtgagg gcagagtgga gctcaaaacg
1861 cttggtgcct ggggatccct ctgtaactct cactgggaca tagaagatgc ccatgttctt
1921 tgccagcagc ttaaatgtgg agttgccctt tctaccccag gaggagcacg ttttggaaaa
1981 ggaaatggtc agatctggag gcatatgttt cactgcactg ggactgagca gcacatggga
2041 gattgtcctg taactgctct aggtgcttca ttatgtcctt cagagcaagt ggcctctgta
2101 atctgctcag gaaaccagtc ccaaacactg tcctcgtgca attcatcgtc tttgggccca
2161 acaaggccta ccattccaga agaaagtgct gtggcctgca tagagagtgg tcaacttcgc
2221 ctggtaaatg gaggaggtcg ctgtgctggg agagtagaga tctatcatga gggctcctgg
2281 ggcaccatct gtgatgacag ctgggacctg agtgatgccc acgtggtttg cagacagctg
2341 ggctgtggag aggccattaa tgccactggt tctgctcatt ttggggaagg aacagggccc
2401 atctggctgg atgagatgaa atgcaatgga aaagaatccc gcatttggca gtgccattca
2461 cacggctggg ggcagcaaaa ttgcaggcac aaggaggatg cgggagttat ctgctcagaa
2521 ttcatgtctc tgagactgac cagtgaagcc agcagagagg cctgtgcagg gcgtctggaa
2581 gttttttaca atggagcttg gggcactgtt ggcaagagta gcatgtctga aaccactgtg
2641 ggtgtggtgt gcaggcagct gggctgtgca gacaaaggga aaatcaaccc tgcatcttta
2701 gacaaggcca tgtccattcc catgtgggtg gacaatgttc agtgtccaaa aggacctgac
2761 acgctgtggc agtgcccatc atctccatgg gagaagagac tggccagccc ctcggaggag
2821 acctggatca catgtgacaa caagataaga cttcaggaag gacccacttc ctgttctgga
2881 cgtgtggaga tctggcatgg aggttcctgg gggacagtgt gtgatgactc ttgggacttg
2941 gacgatgctc aggtggtgtg tcaacaactt ggctgtggtc cagctttgaa agcattcaaa
3001 gaagcagagt ttggtcaggg gactggaccg atatggctca atgaagtgaa gtgcaaaggg
3061 aatgagtctt ccttgtggga ttgtcctgcc agacgctggg gccatagtga gtgtgggcac
3121 aaggaagacg ctgcagtgaa ttgcacagat atttcagtgc agaaaacccc acaaaaagcc
3181 acaacaggtc gctcatcccg tcagtcatcc tttattgcag tcgggatcct tggggttgtt
3241 ctgttggcca ttttcgtcgc attattcttc ttgactaaaa agcgaagaca gagacagcgg
3301 cttgcagttt cctcaagagg agagaactta gtccaccaaa ttcaataccg ggagatgaat
3361 tcttgcctga atgcagatga tctggaccta atgaattcct cagaaaattc ccatgagtca
3421 gctgatttca gtgctgctga actaatttct gtgtctaaat ttcttcctat ttctggaatg
3481 gaaaaggagg ccattctgag ccacactgaa aaggaaaatg ggaatttata acccagtgag
3541 ttcagccttt aagatacctt gatgaagacc tggactattg aatggagcag aaattcacct
3601 ctctcactga ctattacagt tgcattttta tggagttctt cttctcctag gattcctaag
3661 actgctgctg aatttataaa aattaagttt gtgaatgtga ctacttagtg gtgtatatga
3721 gactttcaag ggaattaaat aaataaataa gaatgttatt gaaaaaaaaa aaaaaaaaaa
//