LOCUS BC051270 3798 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene
homolog (avian), mRNA (cDNA clone MGC:59921 IMAGE:4871614),
complete cds.
ACCESSION BC051270
VERSION BC051270.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3798)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3798)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: c Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38202216.
FEATURES Location/Qualifiers
source 1..3798
/db_xref="H-InvDB:HIT000099290"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59921 IMAGE:4871614"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3798
/gene="SRC"
/gene_synonym="ASV"
/gene_synonym="c-SRC"
/gene_synonym="p60-Src"
/db_xref="GeneID:6714"
/db_xref="HGNC:HGNC:11283"
/db_xref="MIM:190090"
CDS 103..1713
/gene="SRC"
/gene_synonym="ASV"
/gene_synonym="c-SRC"
/gene_synonym="p60-Src"
/codon_start=1
/product="v-src sarcoma (Schmidt-Ruppin A-2) viral
oncogene homolog (avian)"
/protein_id="AAH51270.2"
/db_xref="GeneID:6714"
/db_xref="HGNC:HGNC:11283"
/db_xref="MIM:190090"
/translation="MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASA
DGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETD
LSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRE
SERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYIT
SRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKL
GQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE
EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRA
ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWS
FGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEE
RPTFEYLQAFLEDYFTSTEPQYQPGENL"
BASE COUNT 775 a 1142 c 1123 g 758 t
ORIGIN
1 ggcctctatt tcgagacccc tgactccaca cctggtgttt gtgccaagac cccaggctgc
61 ctcccaggtc ctctgggaca gcccctgcct tctaccagga ccatgggtag caacaagagc
121 aagcccaagg atgccagcca gcggcgccgc agcctggagc ccgccgagaa cgtgcacggc
181 gctggcgggg gcgctttccc cgcctcgcag acccccagca agccagcctc ggccgacggc
241 caccgcggcc ccagcgcggc cttcgccccc gcggccgccg agcccaagct gttcggaggc
301 ttcaactcct cggacaccgt cacctccccg cagagggcgg gcccgctggc cggtggagtg
361 accacctttg tggccctcta tgactatgag tctaggacgg agacagacct gtccttcaag
421 aaaggcgagc ggctccagat tgtcaacaac acagagggag actggtggct ggcccactcg
481 ctcagcacag gacagacagg ctacatcccc agcaactacg tggcgccctc cgactccatc
541 caggctgagg agtggtattt tggcaagatc accagacggg agtcagagcg gttactgctc
601 aatgcagaga acccgagagg gaccttcctc gtgcgagaaa gtgagaccac gaaaggtgcc
661 tactgcctct cagtgtctga cttcgacaac gccaagggcc tcaacgtgaa gcactacaag
721 atccgcaagc tggacagcgg cggcttctac atcacctccc gcacccagtt caacagcctg
781 cagcagctgg tggcctacta ctccaaacac gccgatggcc tgtgccaccg cctcaccacc
841 gtgtgcccca cgtccaagcc gcagactcag ggcctggcca aggatgcctg ggagatccct
901 cgggagtcgc tgcggctgga ggtcaagctg ggccagggct gctttggcga ggtgtggatg
961 gggacctgga acggtaccac cagggtggcc atcaaaaccc tgaagcctgg cacgatgtct
1021 ccagaggcct tcctgcagga ggcccaggtc atgaagaagc tgaggcatga gaagctggtg
1081 cagttgtatg ctgtggtttc agaggagccc atttacatcg tcacggagta catgagcaag
1141 gggagtttgc tggactttct caagggggag acaggcaagt acctgcggct gcctcagctg
1201 gtggacatgg ctgctcagat cgcctcaggc atggcgtacg tggagcggat gaactacgtc
1261 caccgggacc ttcgtgcagc caacatcctg gtgggagaga acctggtgtg caaagtggcc
1321 gactttgggc tggctcggct cattgaagac aatgagtaca cggcgcggca aggtgccaaa
1381 ttccccatca agtggacggc tccagaagct gccctctatg gccgcttcac catcaagtcg
1441 gacgtgtggt ccttcgggat cctgctgact gagctcacca caaagggacg ggtgccctac
1501 cctgggatgg tgaaccgcga ggtgctggac caggtggagc ggggctaccg gatgccctgc
1561 ccgccggagt gtcccgagtc cctgcacgac ctcatgtgcc agtgctggcg gaaggagcct
1621 gaggagcggc ccaccttcga gtacctgcag gccttcctgg aggactactt cacgtccacc
1681 gagccccagt accagcccgg ggagaacctc taggcacagg cgggcccaga ccggcttctc
1741 ggcttggatc ctgggctggg tggcccctgt ctcggggctt gccccactct gcctgcctgc
1801 tgttggtcct ctctctgtgg ggctgaattg ccaggggcga ggcccttcct ctttggtggc
1861 atggaagggg cttctggacc tagggtggcc tgagagggcg gtgggtatgc gagaccagca
1921 cggtgactct gtccagctcc cgctgtggcc gcacgcctct ccctgcactc cctcctggag
1981 ctctgtgggt ctctggaaga ggaaccagga gaagggctgg ggccggggct gagggtgccc
2041 ttttccagcc tcagcctact ccgctcactg aactccttcc ccacttctgt gccacccccg
2101 gtctatgtcg agagctggcc aaagagcctt tccaaagagg agcgatgggc ccctggcccc
2161 gcctgcctgc caccctgccc cttgccatcc attctggaaa cacctgtagg cagaggctgc
2221 cgagacagac cctctgccgc tgcttccagg ctgggcagca caaggccttg cctggcctga
2281 tgatggtggg tgggtgggat gagtaccccc tcaaaccctg ccctccttag acctgaggga
2341 cccttcgaga tcatcacttc cttgccccca tttcacccat ggggagacag ttgagagcgg
2401 ggatgtgaca tgcccaaggc cacggagcag ttcagagtgg aggcgggctt ggaacccggt
2461 gctccctctg tcatcctcag gaaccaacaa ttcgtcggag gcatcatgga aagactggga
2521 cagcccagga aacaaggggt ctgaggatgc attcgagatg gcagattccc actgccgctg
2581 cccgctcagc ccagctgttg ggaacagcat ggaggcagat gtggggctga gctggggaat
2641 cagggtaaaa ggtgcaggtg tggagagaga ggcttcaatc ggcttgtggg tgatgtttga
2701 ccttcagagc cagccggcta tgaaagggag cgagcccctc ggctctggag gcaatcaagc
2761 agacatagaa gagccaagag tccaggaggc cctggtcctg gcctccttcc ccgtactttg
2821 tcccgtggca tttcaattcc tggccctgtt ctcctcccca agtcggcacc ctttaactca
2881 tgaggaggga aaagagtgcc taagcggggg tgaaagagga cgtgttaccc actgccatgc
2941 accaggactg gctgtgtaac cttgggtggc ccctgctgtc tctctgggct gcagagtctg
3001 ccccacatgt ggccatggcc tctgcaactg ctcagctctg gtccaggccc tgtggcagga
3061 cacacatggt gagcctagcc ctgggacatc aggagactgg gctctggctc tgttcggcct
3121 ttgggtgtgt ggtggattct ccctgggcct cagtgtgccc atctgtaaag gggcagctga
3181 cagtttgtgg catcttgcca agggtccctg tgtgtgtgta tgtgtgtgca tgtgtgcgtg
3241 tctccatgtg cgtccatatt taacatgtaa aaatgtcccc cccgctccgt cccccaaaca
3301 tgttgtacat ttcaccatgg ccccctcatc atagcaataa cattcccact gccaggggtt
3361 cttgagccag ccaggccctg ccagtgggga aggaggccaa gcagtgcctg cctatgaaat
3421 ttcaactttt cctttcatac gtctttatta cccaagtctt ctcccgtcca ttccagtcaa
3481 atctgggctc actcacccca gcgagctctc aaatccctct ccaactgcct aaggcccttt
3541 gtgtaaggtg tcttaatact gtcctttttt tttttttaac agtgttttgt agatttcaga
3601 tgactatgca gaggcctggg ggacccctgg ctctgggccg ggcctggggc tccgaaattc
3661 caaggcccag acttgcgggg ggtggggggg tatccagaat tggttgtaaa tactttgcat
3721 attgtctgat taaacacaaa cagacctcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3781 aaaaaaaaaa aaaaaaaa
//